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DROME:LAMC
Contents
| Species (Taxon ID) | Drosophila melanogaster (Fruit fly). (7227) | |
| Gene Name(s) | LamC | |
| Protein Name(s) | Lamin-C
pG-IF | |
| External Links | ||
| UniProt | Q03427 | |
| EMBL | L07933 X75886 AE013599 AY095046 | |
| PIR | S49020 | |
| RefSeq | NP_523742.2 | |
| UniGene | Dm.2782 | |
| ProteinModelPortal | Q03427 | |
| SMR | Q03427 | |
| BioGrid | 62363 | |
| MINT | MINT-1329471 | |
| PaxDb | Q03427 | |
| EnsemblMetazoa | FBtr0087512 | |
| GeneID | 36615 | |
| KEGG | dme:Dmel_CG10119 | |
| CTD | 36615 | |
| FlyBase | FBgn0010397 | |
| eggNOG | NOG325506 | |
| GeneTree | ENSGT00760000118905 | |
| InParanoid | Q03427 | |
| KO | K07611 | |
| OrthoDB | EOG7MD4PW | |
| PhylomeDB | Q03427 | |
| Reactome | REACT_180717 REACT_219169 REACT_249949 | |
| GenomeRNAi | 36615 | |
| NextBio | 799505 | |
| Proteomes | UP000000803 | |
| Bgee | Q03427 | |
| GO | GO:0005638 GO:0005637 GO:0005652 GO:0034399 GO:0070732 GO:0005198 GO:0006325 GO:0006342 GO:0060415 GO:0031081 GO:0030833 GO:0035989 | |
| Gene3D | 2.60.40.1260 | |
| InterPro | IPR001664 IPR027696 IPR001322 | |
| PANTHER | PTHR23239 PTHR23239:SF142 | |
| Pfam | PF00038 PF00932 | |
| SUPFAM | SSF74853 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
involved_in |
GO:0007112 |
male meiosis cytokinesis |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005652 |
nuclear lamina |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0035989 |
tendon development |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0031081 |
nuclear pore distribution |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0060415 |
muscle tissue morphogenesis |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0034399 |
nuclear periphery |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005200 |
structural constituent of cytoskeleton |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006342 |
chromatin silencing |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0030833 |
regulation of actin filament polymerization |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006325 |
chromatin organization |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0031081 |
nuclear pore distribution |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0070732 |
spindle envelope |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
colocalizes_with |
GO:0005635 |
nuclear envelope |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005638 |
lamin filament |
ECO:0000303 |
author statement without traceable support used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005638 |
lamin filament |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005652 |
nuclear lamina |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007010 |
cytoskeleton organization |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0005200 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0016020 |
membrane |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0031081 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0016020 |
membrane |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0031081 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0005198 |
structural molecule activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005882 |
intermediate filament |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005882 |
intermediate filament |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005652 |
nuclear lamina |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Hayashi, D et al. (2016) B-type nuclear lamin and the nuclear pore complex Nup107-160 influences maintenance of the spindle envelope required for cytokinesis in Drosophila male meiosis. Biol Open 5 1011-21 PubMed GONUTS page
- ↑ Uchino, R et al. (2013) Loss of Drosophila A-type lamin C initially causes tendon abnormality including disintegration of cytoskeleton and nuclear lamina in muscular defects. Dev. Biol. 373 216-27 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 3.4 3.5 Dialynas, G et al. (2010) The role of Drosophila Lamin C in muscle function and gene expression. Development 137 3067-77 PubMed GONUTS page
- ↑ Gurudatta, BV et al. (2010) Lamin C and chromatin organization in Drosophila. J. Genet. 89 37-49 PubMed GONUTS page
- ↑ Schulze, SR et al. (2009) A comparative study of Drosophila and human A-type lamins. PLoS ONE 4 e7564 PubMed GONUTS page
- ↑ Katsani, KR et al. (2008) In vivo dynamics of Drosophila nuclear envelope components. Mol. Biol. Cell 19 3652-66 PubMed GONUTS page
- ↑ Prüfert, K et al. (2004) The lamin CxxM motif promotes nuclear membrane growth. J. Cell. Sci. 117 6105-16 PubMed GONUTS page
- ↑ Bellaiche, Y et al. (1998) Tout-velu is a Drosophila homologue of the putative tumour suppressor EXT-1 and is needed for Hh diffusion. Nature 394 85-8 PubMed GONUTS page
- ↑ Klapper, M et al. (1997) Assembly of A- and B-type lamins studied in vivo with the baculovirus system. J. Cell. Sci. 110 ( Pt 20) 2519-32 PubMed GONUTS page
- ↑ Riemer, D et al. (1995) Expression of Drosophila lamin C is developmentally regulated: analogies with vertebrate A-type lamins. J. Cell. Sci. 108 ( Pt 10) 3189-98 PubMed GONUTS page
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