It is now the 1st OPEN Period for CACAO Fall 2017! It will end on Sunday September 24, 2017 at 11:59 pm CDT
This is your chance to make annotations OR challenge other team's annotations. You may also DEFEND or suggest improvements to your own annotations IF they have been challenged. Please note, although we ENCOURAGE challenges, an excess of identical challenges that do not appear to be applicable to the annotation or well thought out will be considered spam and ignored.

Have any questions? Please email us at ecoliwiki@gmail.com

DROME:AMOS

From GONUTS
Jump to: navigation, search
Species (Taxon ID) Drosophila melanogaster (Fruit fly). (7227)
Gene Name(s) amos (synonyms: Roi, rolo)
Protein Name(s) Basic helix-loop-helix transcription factor amos

Absent MD neurons and olfactory sensilla protein Amos protein Reduced olfactory organs protein Rough eye protein

External Links
UniProt Q9Y0A7
EMBL AF166113
AE014134
BT028832
BT028865
RefSeq NP_477446.1
UniGene Dm.4695
ProteinModelPortal Q9Y0A7
SMR Q9Y0A7
BioGrid 61105
DIP DIP-18188N
IntAct Q9Y0A7
MINT MINT-340393
PaxDb Q9Y0A7
EnsemblMetazoa FBtr0081081
GeneID 35110
KEGG dme:Dmel_CG10393
CTD 35110
FlyBase FBgn0003270
eggNOG NOG267878
GeneTree ENSGT00680000099860
InParanoid Q9Y0A7
OMA MAQAYIG
OrthoDB EOG7N37G2
PhylomeDB Q9Y0A7
GenomeRNAi 35110
NextBio 791914
PRO PR:Q9Y0A7
Proteomes UP000000803
Bgee Q9Y0A7
GO GO:0005634
GO:0046982
GO:0048813
GO:0006355
GO:0008052
GO:0007423
GO:0016360
GO:0006351
Gene3D 4.10.280.10
InterPro IPR011598
Pfam PF00010
SMART SM00353
SUPFAM SSF47459
PROSITE PS50888

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005634

nucleus

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0539

C

Seeded From UniProt

complete

GO:0005634

nucleus

GO_REF:0000039

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

GO:0006351

transcription, DNA-templated

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0804

P

Seeded From UniProt

complete

GO:0006355

regulation of transcription, DNA-templated

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0805

P

Seeded From UniProt

complete

GO:0007275

multicellular organismal development

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0217

P

Seeded From UniProt

complete

GO:0007399

nervous system development

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0524

P

Seeded From UniProt

complete

GO:0007423

sensory organ development

PMID:12142008[1]

TAS: Traceable Author Statement

P

Seeded From UniProt

complete

GO:0007423

sensory organ development

PMID:17260155[2]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0008052

sensory organ boundary specification

PMID:12702684[3]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0008052

sensory organ boundary specification

PMID:12702685[4]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0016360

sensory organ precursor cell fate determination

PMID:10707972[5]

IDA: Inferred from Direct Assay

P

Seeded From UniProt

complete

GO:0016360

sensory organ precursor cell fate determination

PMID:15313555[6]

TAS: Traceable Author Statement

P

Seeded From UniProt

complete

GO:0016360

sensory organ precursor cell fate determination

PMID:17709231[7]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0030154

cell differentiation

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0221

P

Seeded From UniProt

complete

GO:0046982

protein heterodimerization activity

PMID:10707972[5]

IPI: Inferred from Physical Interaction

FB:FBgn0267821

F

Seeded From UniProt

complete

GO:0046983

protein dimerization activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR011598

F

Seeded From UniProt

complete

GO:0048813

dendrite morphogenesis

PMID:23977298[8]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

contributes_to

GO:0001012

RNA polymerase II regulatory region DNA binding

PMID:10707972[5]

IPI: Inferred from Physical Interaction

FB:FBgn0267821

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Skaer, N et al. (2002) Gene duplication at the achaete-scute complex and morphological complexity of the peripheral nervous system in Diptera. Trends Genet. 18 399-405 PubMed GONUTS page
  2. Grillenzoni, N et al. (2007) Role of proneural genes in the formation of the larval olfactory organ of Drosophila. Dev. Genes Evol. 217 209-19 PubMed GONUTS page
  3. Villa-Cuesta, E et al. (2003) Tufted is a gain-of-function allele that promotes ectopic expression of the proneural gene amos in Drosophila. Genetics 163 1403-12 PubMed GONUTS page
  4. Lai, EC (2003) Drosophila tufted is a gain-of-function allele of the proneural gene amos. Genetics 163 1413-25 PubMed GONUTS page
  5. 5.0 5.1 5.2 Huang, ML et al. (2000) The proneural gene amos promotes multiple dendritic neuron formation in the Drosophila peripheral nervous system. Neuron 25 57-67 PubMed GONUTS page
  6. Hallem, EA & Carlson, JR (2004) The odor coding system of Drosophila. Trends Genet. 20 453-9 PubMed GONUTS page
  7. Maung, SM & Jarman, AP () Functional distinctness of closely related transcription factors: a comparison of the Atonal and Amos proneural factors. Mech. Dev. 124 647-56 PubMed GONUTS page
  8. Iyer, EP et al. (2013) Functional genomic analyses of two morphologically distinct classes of Drosophila sensory neurons: post-mitotic roles of transcription factors in dendritic patterning. PLoS ONE 8 e72434 PubMed GONUTS page