DROME:A0A0B4JCQ5

Species (Taxon ID)	Drosophila melanogaster (Fruit fly). (7227)
Gene Name(s)	No Information Provided.
Protein Name(s)	Lipin, isoform D (ECO:0000313 with EMBL:ADV37124.1)
External Links
UniProt	A0A0B4JCQ5
EMBL	AE013599
RefSeq	NP_001188875.1
UniGene	Dm.522
STRING	7227.FBpp0292618
PaxDb	A0A0B4JCQ5
GeneID	35790
CTD	35790
FlyBase	FBgn0263593
eggNOG	COG5083 KOG2116
Proteomes	UP000000803
GO	GO:0005737 GO:0035183 GO:0005634 GO:0008195 GO:0003713 GO:0016311 GO:0009062 GO:0007474 GO:0055088 GO:0030514 GO:0045944 GO:0010565 GO:0019217 GO:0006357 GO:0042594 GO:0019432
Gene3D	3.40.50.1000
InterPro	IPR023214 IPR031703 IPR007651 IPR013209 IPR031315
Pfam	PF16876 PF04571 PF08235
SMART	SM00775
SUPFAM	SSF56784

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
involved_in	GO:0045944	positive regulation of transcription by RNA polymerase II	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1891340 MGI:MGI:1891341 PANTHER:PTN000953144	P	Seeded From UniProt	complete
involved_in	GO:0032869	cellular response to insulin stimulus	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0263593 MGI:MGI:1891340 PANTHER:PTN000953144 RGD:1307646	P	Seeded From UniProt	complete
involved_in	GO:0019432	triglyceride biosynthetic process	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0263593 PANTHER:PTN000256565 SGD:S000004775	P	Seeded From UniProt	complete
involved_in	GO:0009062	fatty acid catabolic process	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1891340 PANTHER:PTN000256565	P	Seeded From UniProt	complete
enables	GO:0008195	phosphatidate phosphatase activity	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0263593 MGI:MGI:1891340 MGI:MGI:1891341 MGI:MGI:1891342 PANTHER:PTN000256564 SGD:S000004775 TAIR:locus:2075019 UniProtKB:Q14693 UniProtKB:Q92539 UniProtKB:Q9BQK8 UniProtKB:Q9FMN2	F	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0263593 MGI:MGI:1891340 PANTHER:PTN000256565	C	Seeded From UniProt	complete
enables	GO:0003713	transcription coactivator activity	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1891340 MGI:MGI:1891341 PANTHER:PTN000953144	F	Seeded From UniProt	complete
involved_in	GO:0007474	imaginal disc-derived wing vein specification	PMID:21790556^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0030514	negative regulation of BMP signaling pathway	PMID:21790556^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0030514	negative regulation of BMP signaling pathway	PMID:21790556^[2]	ECO:0000316	genetic interaction evidence used in manual assertion	FB:FBgn0020493	P	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:21300783^[3]	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
involved_in	GO:0019432	triglyceride biosynthetic process	PMID:21300783^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0055088	lipid homeostasis	PMID:21300783^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0042594	response to starvation	PMID:21300783^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	PMID:21300783^[3]	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
involved_in	GO:0010565	regulation of cellular ketone metabolic process	PMID:21300783^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0019217	regulation of fatty acid metabolic process	PMID:21300783^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	PMID:20977671^[4]	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
enables	GO:0003713	transcription coactivator activity	PMID:20977671^[4]	ECO:0000250	sequence similarity evidence used in manual assertion	MGI:MGI:1891340	F	Seeded From UniProt	complete
enables	GO:0008195	phosphatidate phosphatase activity	PMID:20977671^[4]	ECO:0000250	sequence similarity evidence used in manual assertion	MGI:MGI:1891340	F	Seeded From UniProt	complete
involved_in	GO:0006357	regulation of transcription by RNA polymerase II	PMID:20977671^[4]	ECO:0000250	sequence similarity evidence used in manual assertion	MGI:MGI:1891340	P	Seeded From UniProt	complete
part_of	GO:0035183	female germline ring canal inner rim	PMID:20977671^[4]	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
involved_in	GO:0016311	dephosphorylation	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0008195	P	Seeded From UniProt	complete
involved_in	GO:0016311	dephosphorylation	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0008195	P	Seeded From UniProt	complete
involved_in	GO:0016311	dephosphorylation	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0008195	P	Seeded From UniProt	complete
enables	GO:0008195	phosphatidate phosphatase activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:3.1.3.4	F	Seeded From UniProt	complete
enables	GO:0016787	hydrolase activity	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0378	F	Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 ^1.6 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
↑ ^2.0 ^2.1 ^2.2 Liu, Z et al. (2011) Negative modulation of bone morphogenetic protein signaling by Dullard during wing vein formation in Drosophila. Dev. Growth Differ. 53 822-41 PubMed GONUTS page
↑ ^3.0 ^3.1 ^3.2 ^3.3 ^3.4 ^3.5 ^3.6 Ugrankar, R et al. (2011) Lipin is a central regulator of adipose tissue development and function in Drosophila melanogaster. Mol. Cell. Biol. 31 1646-56 PubMed GONUTS page
↑ ^4.0 ^4.1 ^4.2 ^4.3 ^4.4 Valente, V et al. (2010) Drosophila melanogaster lipins are tissue-regulated and developmentally regulated and present specific subcellular distributions. FEBS J. 277 4775-88 PubMed GONUTS page

[PMID:21873635-1] 1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 ^1.6 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:21790556-2] 2.0 ^2.1 ^2.2 Liu, Z et al. (2011) Negative modulation of bone morphogenetic protein signaling by Dullard during wing vein formation in Drosophila. Dev. Growth Differ. 53 822-41 PubMed GONUTS page

[PMID:21300783-3] 3.0 ^3.1 ^3.2 ^3.3 ^3.4 ^3.5 ^3.6 Ugrankar, R et al. (2011) Lipin is a central regulator of adipose tissue development and function in Drosophila melanogaster. Mol. Cell. Biol. 31 1646-56 PubMed GONUTS page

[PMID:20977671-4] 4.0 ^4.1 ^4.2 ^4.3 ^4.4 Valente, V et al. (2010) Drosophila melanogaster lipins are tissue-regulated and developmentally regulated and present specific subcellular distributions. FEBS J. 277 4775-88 PubMed GONUTS page

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DROME:A0A0B4JCQ5

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