It is now the 1st OPEN Period for CACAO Fall 2017! It will end on Sunday September 24, 2017 at 11:59 pm CDT
This is your chance to make annotations OR challenge other team's annotations. You may also DEFEND or suggest improvements to your own annotations IF they have been challenged. Please note, although we ENCOURAGE challenges, an excess of identical challenges that do not appear to be applicable to the annotation or well thought out will be considered spam and ignored.

Have any questions? Please email us at ecoliwiki@gmail.com

DANRE:VANG2

From GONUTS
Jump to: navigation, search
Species (Taxon ID) Danio rerio (Zebrafish) (Brachydanio rerio). (7955)
Gene Name(s) vangl2 (ECO:0000312 with ZFIN:ZDB-GENE-020507-3)
Protein Name(s) Vang-like protein 2

Protein strabismus Protein trilobite Van Gogh-like protein 2

External Links
UniProt Q8UVJ6
EMBL AF428249
BC065983
RefSeq NP_705960.1
UniGene Dr.91583
BioGrid 79765
STRING 7955.ENSDARP00000031546
Ensembl ENSDART00000033316
GeneID 245949
KEGG dre:245949
CTD 57216
ZFIN ZDB-GENE-020507-3
eggNOG NOG268286
GeneTree ENSGT00390000012496
HOGENOM HOG000230590
HOVERGEN HBG058215
InParanoid Q8UVJ6
KO K04510
OMA MWHRESD
OrthoDB EOG7MSMNR
PhylomeDB Q8UVJ6
TreeFam TF313467
Reactome REACT_202432
REACT_223798
NextBio 20797201
PRO PR:Q8UVJ6
Proteomes UP000000437
Bgee Q8UVJ6
GO GO:0016021
GO:0005886
GO:0003401
GO:0060070
GO:0021535
GO:0042074
GO:0000902
GO:0044782
GO:0035844
GO:0060026
GO:0060027
GO:0048048
GO:0030010
GO:0000132
GO:0001736
GO:0007163
GO:0001654
GO:0060972
GO:0097475
GO:0014812
GO:0001839
GO:0021915
GO:0001841
GO:0001764
GO:0030903
GO:0045813
GO:0036342
GO:0030111
GO:0001756
GO:0055002
GO:0060071
InterPro IPR009539
PANTHER PTHR20886
Pfam PF06638
PIRSF PIRSF007991

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000132

establishment of mitotic spindle orientation

PMID:15254551[1]

IMP: Inferred from Mutant Phenotype

P

complete

GO:0000902

cell morphogenesis

PMID:12105418[2]

IMP: Inferred from Mutant Phenotype

P

complete

GO:0001654

eye development

PMID:9808788[3]

IGI: Inferred from Genetic Interaction

UniProtKB:Q90Z52

P

complete

GO:0001736

establishment of planar polarity

PMID:12105418[2]

IMP: Inferred from Mutant Phenotype

P

complete

GO:0001756

somitogenesis

PMID:10996075[4]

IGI: Inferred from Genetic Interaction

UniProtKB:Q90Z52

P

complete

GO:0001764

neuron migration

PMID:11820812[5]

IMP: Inferred from Mutant Phenotype

P

complete

GO:0001764

neuron migration

PMID:12105418[2]

IMP: Inferred from Mutant Phenotype

P

complete

GO:0001764

neuron migration

PMID:12105418[2]

IMP: Inferred from Mutant Phenotype

P

complete

GO:0001764

neuron migration

PMID:12105418[2]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-041217-5

P

complete

GO:0001764

neuron migration

PMID:12874125[6]

IGI: Inferred from Genetic Interaction

UniProtKB:Q6WGK5

P

complete

GO:0001764

neuron migration

PMID:19013446[7]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-041217-5

P

complete

GO:0001839

neural plate morphogenesis

PMID:16502420[8]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-041217-5

P

complete

GO:0001841

neural tube formation

PMID:16407953[9]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-1083

P

complete

GO:0005515

protein binding

PMID:11780127[10]

IPI: Inferred from Physical Interaction

UniProtKB:P51142

F

complete

GO:0005886

plasma membrane

GO_REF:0000024

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:Q90X64

C

complete

GO:0007163

establishment or maintenance of cell polarity

PMID:12105418[2]

IMP: Inferred from Mutant Phenotype

P

complete

GO:0007275

multicellular organismal development

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR009539

P

complete

GO:0007275

multicellular organismal development

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0217

P

complete

GO:0007369

gastrulation

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0306

P

complete

GO:0007399

nervous system development

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0524

P

complete

GO:0014812

muscle cell migration

PMID:17849437[11]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-GENO-070906-2

P

complete

GO:0014812

muscle cell migration

PMID:17849437[11]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-070305-2

P

complete

GO:0016020

membrane

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0472

C

complete

GO:0016020

membrane

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0162

C

complete

GO:0016021

integral to membrane

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR009539

C

complete

GO:0016021

integral to membrane

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0812

C

complete

GO:0016021

integral to membrane

PMID:11780127[10]

NAS: Non-traceable Author Statement

C

complete

GO:0016055

Wnt receptor signaling pathway

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0879

P

complete

GO:0021535

cell migration in hindbrain

PMID:17392791[12]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-070305-2

P

complete

GO:0021915

neural tube development

PMID:16407953[9]

IMP: Inferred from Mutant Phenotype

P

complete

GO:0030010

establishment of cell polarity

PMID:12105418[2]

IMP: Inferred from Mutant Phenotype

P

complete

GO:0030111

regulation of Wnt receptor signaling pathway

PMID:11780127[10]

IMP: Inferred from Mutant Phenotype

P

complete

GO:0030154

cell differentiation

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0221

P

complete

GO:0030903

notochord development

PMID:9007234[13]

IMP: Inferred from Mutant Phenotype

P

complete

GO:0035121

tail morphogenesis

PMID:18045497[14]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-041217-5

P

complete

GO:0042074

cell migration involved in gastrulation

PMID:11780127[10]

IMP: Inferred from Mutant Phenotype

P

complete

GO:0042074

cell migration involved in gastrulation

PMID:12105418[2]

IMP: Inferred from Mutant Phenotype

P

complete

GO:0042074

cell migration involved in gastrulation

PMID:15882862[15]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-050823-1

P

complete

GO:0042074

cell migration involved in gastrulation

PMID:15882862[15]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-050823-4

P

complete

GO:0045813

positive regulation of Wnt receptor signaling pathway, calcium modulating pathway

PMID:11780127[10]

IMP: Inferred from Mutant Phenotype

P

complete

GO:0048048

embryonic eye morphogenesis

PMID:9142986[16]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-1037

P

complete

GO:0055002

striated muscle cell development

PMID:17849437[11]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-GENO-070906-2

P

complete

GO:0055002

striated muscle cell development

PMID:17849437[11]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-070305-2

P

complete

GO:0060026

convergent extension

PMID:12105418[2]

IDA: Inferred from Direct Assay

P

complete

GO:0060026

convergent extension

PMID:12105418[2]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-041217-5

P

complete

GO:0060026

convergent extension

PMID:17239849[17]

IPI: Inferred from Physical Interaction

UniProtKB:Q90Z52

P

complete

GO:0060026

convergent extension

PMID:18195109[18]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-080416-1

P

complete

GO:0060026

convergent extension

PMID:20043994[19]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-041217-5

P

complete

GO:0060027

convergent extension involved in gastrulation

PMID:10992326[20]

IMP: Inferred from Mutant Phenotype

P

complete

GO:0060027

convergent extension involved in gastrulation

PMID:12874125[6]

IGI: Inferred from Genetic Interaction

UniProtKB:Q6WGK5

P

complete

GO:0060027

convergent extension involved in gastrulation

PMID:9007230[21]

IMP: Inferred from Mutant Phenotype

P

complete

GO:0000132

establishment of mitotic spindle orientation

PMID:15254551[1]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0060027

convergent extension involved in gastrulation

PMID:9007236[22]

IMP: Inferred from Mutant Phenotype

P

complete

GO:0000132

establishment of mitotic spindle orientation

PMID:23213452[23]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-MRPHLNO-110614-5
ZFIN:ZDB-MRPHLNO-130117-3

P

Seeded From UniProt

complete

GO:0060027

convergent extension involved in gastrulation

PMID:9808788[3]

IGI: Inferred from Genetic Interaction

UniProtKB:Q90Z52

P

complete

GO:0000132

establishment of mitotic spindle orientation

PMID:23213452[23]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-110614-5

P

Seeded From UniProt

complete

GO:0060070

canonical Wnt receptor signaling pathway

PMID:11780127[10]

IMP: Inferred from Mutant Phenotype

P

complete

GO:0000902

cell morphogenesis

PMID:12105418[2]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0060071

Wnt receptor signaling pathway, planar cell polarity pathway

PMID:11780127[10]

IMP: Inferred from Mutant Phenotype

P

complete

GO:0001654

eye development

PMID:9808788[3]

IGI: Inferred from Genetic Interaction

UniProtKB:Q90Z52

P

Seeded From UniProt

complete

GO:0060071

Wnt receptor signaling pathway, planar cell polarity pathway

PMID:12105418[2]

IMP: Inferred from Mutant Phenotype

P

complete

GO:0001736

establishment of planar polarity

PMID:12105418[2]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0001736

establishment of planar polarity

PMID:21602787[24]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-MRPHLNO-041217-5
ZFIN:ZDB-MRPHLNO-080107-2

P

Seeded From UniProt

complete

GO:0001736

establishment of planar polarity

PMID:21602787[24]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-MRPHLNO-041217-5
ZFIN:ZDB-MRPHLNO-080929-3

P

Seeded From UniProt

complete

GO:0001736

establishment of planar polarity

PMID:21602787[24]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-MRPHLNO-041217-5
ZFIN:ZDB-MRPHLNO-120402-3

P

Seeded From UniProt

complete

GO:0001736

establishment of planar polarity

PMID:21693519[25]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-041217-5

P

Seeded From UniProt

complete

GO:0001756

somitogenesis

PMID:10996075[4]

IGI: Inferred from Genetic Interaction

UniProtKB:Q90Z52

P

Seeded From UniProt

complete

GO:0001764

neuron migration

PMID:11820812[5]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0001764

neuron migration

PMID:12105418[2]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0001764

neuron migration

PMID:12105418[2]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0001764

neuron migration

PMID:12105418[2]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-041217-5

P

Seeded From UniProt

complete

GO:0001764

neuron migration

PMID:12874125[6]

IGI: Inferred from Genetic Interaction

UniProtKB:Q6WGK5

P

Seeded From UniProt

complete

GO:0001764

neuron migration

PMID:19013446[7]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-MRPHLNO-041217-5
ZFIN:ZDB-MRPHLNO-051128-5

P

Seeded From UniProt

complete

GO:0001764

neuron migration

PMID:19013446[7]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-MRPHLNO-041217-5
ZFIN:ZDB-MRPHLNO-060119-1

P

Seeded From UniProt

complete

GO:0001764

neuron migration

PMID:19013446[7]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-041217-5

P

Seeded From UniProt

complete

GO:0001839

neural plate morphogenesis

PMID:16502420[8]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-041217-5

P

Seeded From UniProt

complete

GO:0001841

neural tube formation

PMID:16407953[9]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-1083

P

Seeded From UniProt

complete

GO:0003401

axis elongation

PMID:21498478[26]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-GENO-070305-2
ZFIN:ZDB-MRPHLNO-110808-1

P

Seeded From UniProt

complete

GO:0003401

axis elongation

PMID:21498478[26]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-MRPHLNO-041217-5
ZFIN:ZDB-MRPHLNO-110808-1

P

Seeded From UniProt

complete

GO:0005515

protein binding

PMID:11780127[10]

IPI: Inferred from Physical Interaction

UniProtKB:P51142

F

Seeded From UniProt

complete

GO:0005515

protein binding

PMID:24021482[27]

IPI: Inferred from Physical Interaction

ZFIN:ZDB-GENE-030724-5

F

Seeded From UniProt

complete

GO:0005515

protein binding

PMID:25183869[28]

IPI: Inferred from Physical Interaction

ZFIN:ZDB-GENE-141210-1

F

Seeded From UniProt

complete

GO:0005886

plasma membrane

GO_REF:0000024

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:Q90X64

C

Seeded From UniProt

complete

GO:0005886

plasma membrane

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-1003

C

Seeded From UniProt

complete

GO:0005886

plasma membrane

GO_REF:0000039

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0039

C

Seeded From UniProt

complete

GO:0005886

plasma membrane

PMID:21262816[29]

IDA: Inferred from Direct Assay

C

Seeded From UniProt

complete

GO:0007015

actin filament organization

PMID:20643117[30]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-GENO-070305-2
ZFIN:ZDB-MRPHLNO-080918-2

P

Seeded From UniProt

complete

GO:0007015

actin filament organization

PMID:20643117[30]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-070305-2

P

Seeded From UniProt

complete

GO:0007163

establishment or maintenance of cell polarity

PMID:12105418[2]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0007275

multicellular organismal development

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR009539

P

Seeded From UniProt

complete

GO:0007275

multicellular organismal development

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0217

P

Seeded From UniProt

complete

GO:0007369

gastrulation

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0306

P

Seeded From UniProt

complete

GO:0007399

nervous system development

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0524

P

Seeded From UniProt

complete

GO:0014812

muscle cell migration

PMID:17849437[11]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-GENO-070906-2

P

Seeded From UniProt

complete

GO:0014812

muscle cell migration

PMID:17849437[11]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-070305-2

P

Seeded From UniProt

complete

GO:0016020

membrane

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

GO:0016021

integral component of membrane

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR009539

C

Seeded From UniProt

complete

GO:0016021

integral component of membrane

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

GO:0016021

integral component of membrane

PMID:11780127[10]

NAS: Non-traceable Author Statement

C

Seeded From UniProt

complete

GO:0016055

Wnt signaling pathway

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0879

P

Seeded From UniProt

complete

GO:0021535

cell migration in hindbrain

PMID:17392791[12]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-070305-2

P

Seeded From UniProt

complete

GO:0021915

neural tube development

PMID:16407953[9]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0030010

establishment of cell polarity

PMID:12105418[2]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0030111

regulation of Wnt signaling pathway

PMID:11780127[10]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0030154

cell differentiation

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0221

P

Seeded From UniProt

complete

GO:0030198

extracellular matrix organization

PMID:24021482[27]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-131216-9

P

Seeded From UniProt

complete

GO:0030903

notochord development

PMID:9007234[13]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0035844

cloaca development

PMID:23213452[23]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-110614-5

P

Seeded From UniProt

complete

GO:0036342

post-anal tail morphogenesis

PMID:18045497[14]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-GENO-070308-4
ZFIN:ZDB-MRPHLNO-041217-5

P

Seeded From UniProt

complete

GO:0036342

post-anal tail morphogenesis

PMID:18045497[14]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-GENO-080422-2
ZFIN:ZDB-MRPHLNO-041217-5

P

Seeded From UniProt

complete

GO:0036342

post-anal tail morphogenesis

PMID:18045497[14]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-041217-5

P

Seeded From UniProt

complete

GO:0042074

cell migration involved in gastrulation

PMID:11780127[10]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0042074

cell migration involved in gastrulation

PMID:12105418[2]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0042074

cell migration involved in gastrulation

PMID:12874125[6]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-GENO-980202-263
ZFIN:ZDB-MRPHLNO-060209-7

P

Seeded From UniProt

complete

GO:0042074

cell migration involved in gastrulation

PMID:15882862[15]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-050823-1

P

Seeded From UniProt

complete

GO:0042074

cell migration involved in gastrulation

PMID:15882862[15]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-050823-4

P

Seeded From UniProt

complete

GO:0042384

cilium assembly

PMID:20643117[30]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-GENO-070305-2
ZFIN:ZDB-MRPHLNO-080918-2

P

Seeded From UniProt

complete

GO:0042384

cilium assembly

PMID:20643117[30]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-070305-2

P

Seeded From UniProt

complete

GO:0044782

cilium organization

PMID:20305649[31]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0045813

positive regulation of Wnt signaling pathway, calcium modulating pathway

PMID:11780127[10]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0048048

embryonic eye morphogenesis

PMID:9142986[16]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-1037

P

Seeded From UniProt

complete

GO:0048570

notochord morphogenesis

PMID:9007234[13]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-120224-10

P

Seeded From UniProt

complete

GO:0048570

notochord morphogenesis

PMID:9007234[13]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-120224-9

P

Seeded From UniProt

complete

GO:0048570

notochord morphogenesis

PMID:9007234[13]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-116

P

Seeded From UniProt

complete

GO:0048570

notochord morphogenesis

PMID:9007234[13]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-263

P

Seeded From UniProt

complete

GO:0048840

otolith development

PMID:20643117[30]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-GENO-070305-2
ZFIN:ZDB-MRPHLNO-080918-2

P

Seeded From UniProt

complete

GO:0048840

otolith development

PMID:20643117[30]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-070305-2

P

Seeded From UniProt

complete

GO:0055002

striated muscle cell development

PMID:17849437[11]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-GENO-070906-2

P

Seeded From UniProt

complete

GO:0055002

striated muscle cell development

PMID:17849437[11]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-070305-2

P

Seeded From UniProt

complete

GO:0060026

convergent extension

PMID:12105418[2]

IDA: Inferred from Direct Assay

P

Seeded From UniProt

complete

GO:0060026

convergent extension

PMID:12105418[2]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-041217-5

P

Seeded From UniProt

complete

GO:0060026

convergent extension

PMID:17239849[17]

IPI: Inferred from Physical Interaction

UniProtKB:Q90Z52

P

Seeded From UniProt

complete

GO:0060026

convergent extension

PMID:18195109[18]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-080416-1

P

Seeded From UniProt

complete

GO:0060026

convergent extension

PMID:20043994[19]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-041217-5

P

Seeded From UniProt

complete

GO:0060026

convergent extension

PMID:20643117[30]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-GENO-070305-2
ZFIN:ZDB-MRPHLNO-080918-2

P

Seeded From UniProt

complete

GO:0060026

convergent extension

PMID:20643117[30]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-070305-2

P

Seeded From UniProt

complete

GO:0060027

convergent extension involved in gastrulation

PMID:10992326[20]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0060027

convergent extension involved in gastrulation

PMID:12874125[6]

IGI: Inferred from Genetic Interaction

UniProtKB:Q6WGK5

P

Seeded From UniProt

complete

GO:0060027

convergent extension involved in gastrulation

PMID:17239849[17]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-GENE-011119-1
ZFIN:ZDB-GENO-070906-2

P

Seeded From UniProt

complete

GO:0060027

convergent extension involved in gastrulation

PMID:18582857[32]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-MRPHLNO-041217-5
ZFIN:ZDB-MRPHLNO-081212-1

P

Seeded From UniProt

complete

GO:0060027

convergent extension involved in gastrulation

PMID:18971206[33]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-GENO-070305-2
ZFIN:ZDB-MRPHLNO-090312-2

P

Seeded From UniProt

complete

GO:0060027

convergent extension involved in gastrulation

PMID:18971206[33]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-MRPHLNO-041217-5
ZFIN:ZDB-MRPHLNO-090312-2

P

Seeded From UniProt

complete

GO:0060027

convergent extension involved in gastrulation

PMID:21262816[29]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-MRPHLNO-041217-5
ZFIN:ZDB-MRPHLNO-110222-3

P

Seeded From UniProt

complete

GO:0060027

convergent extension involved in gastrulation

PMID:23821037[34]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-GENO-131003-4
ZFIN:ZDB-MRPHLNO-131003-5

P

Seeded From UniProt

complete

GO:0060027

convergent extension involved in gastrulation

PMID:25183869[28]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-MRPHLNO-041217-5

P

Seeded From UniProt

complete

GO:0060027

convergent extension involved in gastrulation

PMID:9007230[21]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0060027

convergent extension involved in gastrulation

PMID:9007236[22]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0060027

convergent extension involved in gastrulation

PMID:9808788[3]

IGI: Inferred from Genetic Interaction

UniProtKB:Q90Z52

P

Seeded From UniProt

complete

GO:0060030

dorsal convergence

PMID:9007234[13]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-120224-10

P

Seeded From UniProt

complete

GO:0060030

dorsal convergence

PMID:9007234[13]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-120224-9

P

Seeded From UniProt

complete

GO:0060030

dorsal convergence

PMID:9007234[13]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-116

P

Seeded From UniProt

complete

GO:0060030

dorsal convergence

PMID:9007234[13]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-263

P

Seeded From UniProt

complete

GO:0060070

canonical Wnt signaling pathway

PMID:11780127[10]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0060071

Wnt signaling pathway, planar cell polarity pathway

PMID:11780127[10]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0060071

Wnt signaling pathway, planar cell polarity pathway

PMID:12105418[2]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0060071

Wnt signaling pathway, planar cell polarity pathway

PMID:23821037[34]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-GENO-131003-4
ZFIN:ZDB-MRPHLNO-131003-5

P

Seeded From UniProt

complete

GO:0060972

left/right pattern formation

PMID:20305649[31]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-110823-3

P

Seeded From UniProt

complete

GO:0060972

left/right pattern formation

PMID:20643117[30]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-GENO-070305-2
ZFIN:ZDB-MRPHLNO-080918-2

P

Seeded From UniProt

complete

GO:0060972

left/right pattern formation

PMID:20643117[30]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-070305-2

P

Seeded From UniProt

complete

GO:0097475

motor neuron migration

PMID:23821037[34]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-GENO-131003-7
ZFIN:ZDB-MRPHLNO-131003-5

P

Seeded From UniProt

complete

GO:0097475

motor neuron migration

PMID:23988578[35]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-1495

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Gong, Y et al. (2004) Planar cell polarity signalling controls cell division orientation during zebrafish gastrulation. Nature 430 689-93 PubMed GONUTS page
  2. 2.00 2.01 2.02 2.03 2.04 2.05 2.06 2.07 2.08 2.09 2.10 2.11 2.12 2.13 2.14 2.15 2.16 2.17 2.18 2.19 2.20 2.21 Jessen, JR et al. (2002) Zebrafish trilobite identifies new roles for Strabismus in gastrulation and neuronal movements. Nat. Cell Biol. 4 610-5 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 Marlow, F et al. (1998) Functional interactions of genes mediating convergent extension, knypek and trilobite, during the partitioning of the eye primordium in zebrafish. Dev. Biol. 203 382-99 PubMed GONUTS page
  4. 4.0 4.1 Henry, CA et al. (2000) Somites in zebrafish doubly mutant for knypek and trilobite form without internal mesenchymal cells or compaction. Curr. Biol. 10 1063-6 PubMed GONUTS page
  5. 5.0 5.1 Bingham, S et al. (2002) The Zebrafish trilobite gene is essential for tangential migration of branchiomotor neurons. Dev. Biol. 242 149-60 PubMed GONUTS page
  6. 6.0 6.1 6.2 6.3 6.4 Carreira-Barbosa, F et al. (2003) Prickle 1 regulates cell movements during gastrulation and neuronal migration in zebrafish. Development 130 4037-46 PubMed GONUTS page
  7. 7.0 7.1 7.2 7.3 Sittaramane, V et al. (2009) The cell adhesion molecule Tag1, transmembrane protein Stbm/Vangl2, and Lamininalpha1 exhibit genetic interactions during migration of facial branchiomotor neurons in zebrafish. Dev. Biol. 325 363-73 PubMed GONUTS page
  8. 8.0 8.1 Takamiya, M & Campos-Ortega, JA (2006) Hedgehog signalling controls zebrafish neural keel morphogenesis via its level-dependent effects on neurogenesis. Dev. Dyn. 235 978-97 PubMed GONUTS page
  9. 9.0 9.1 9.2 9.3 Ciruna, B et al. (2006) Planar cell polarity signalling couples cell division and morphogenesis during neurulation. Nature 439 220-4 PubMed GONUTS page
  10. 10.00 10.01 10.02 10.03 10.04 10.05 10.06 10.07 10.08 10.09 10.10 10.11 10.12 10.13 Park, M & Moon, RT (2002) The planar cell-polarity gene stbm regulates cell behaviour and cell fate in vertebrate embryos. Nat. Cell Biol. 4 20-5 PubMed GONUTS page
  11. 11.0 11.1 11.2 11.3 11.4 11.5 11.6 11.7 Yin, C & Solnica-Krezel, L (2007) Convergence and extension movements affect dynamic notochord-somite interactions essential for zebrafish slow muscle morphogenesis. Dev. Dyn. 236 2742-56 PubMed GONUTS page
  12. 12.0 12.1 Tawk, M et al. (2007) A mirror-symmetric cell division that orchestrates neuroepithelial morphogenesis. Nature 446 797-800 PubMed GONUTS page
  13. 13.0 13.1 13.2 13.3 13.4 13.5 13.6 13.7 13.8 13.9 Stemple, DL et al. (1996) Mutations affecting development of the notochord in zebrafish. Development 123 117-28 PubMed GONUTS page
  14. 14.0 14.1 14.2 14.3 Harrington, MJ et al. (2007) Cadherin-mediated adhesion regulates posterior body formation. BMC Dev. Biol. 7 130 PubMed GONUTS page
  15. 15.0 15.1 15.2 15.3 Formstone, CJ & Mason, I (2005) Combinatorial activity of Flamingo proteins directs convergence and extension within the early zebrafish embryo via the planar cell polarity pathway. Dev. Biol. 282 320-35 PubMed GONUTS page
  16. 16.0 16.1 Heisenberg, CP & Nüsslein-Volhard, C (1997) The function of silberblick in the positioning of the eye anlage in the zebrafish embryo. Dev. Biol. 184 85-94 PubMed GONUTS page
  17. 17.0 17.1 17.2 Yin, C & Solnica-Krezel, L (2007) Convergence and extension movements mediate the specification and fate maintenance of zebrafish slow muscle precursors. Dev. Biol. 304 141-55 PubMed GONUTS page
  18. 18.0 18.1 Yin, C et al. (2008) Cooperation of polarized cell intercalations drives convergence and extension of presomitic mesoderm during zebrafish gastrulation. J. Cell Biol. 180 221-32 PubMed GONUTS page
  19. 19.0 19.1 Reynolds, A et al. () VANGL1 rare variants associated with neural tube defects affect convergent extension in zebrafish. Mech. Dev. 127 385-92 PubMed GONUTS page
  20. 20.0 20.1 Sepich, DS et al. (2000) Role of the zebrafish trilobite locus in gastrulation movements of convergence and extension. Genesis 27 159-73 PubMed GONUTS page
  21. 21.0 21.1 Solnica-Krezel, L et al. (1996) Mutations affecting cell fates and cellular rearrangements during gastrulation in zebrafish. Development 123 67-80 PubMed GONUTS page
  22. 22.0 22.1 Hammerschmidt, M et al. (1996) Mutations affecting morphogenesis during gastrulation and tail formation in the zebrafish, Danio rerio. Development 123 143-51 PubMed GONUTS page
  23. 23.0 23.1 23.2 Bubenshchikova, E et al. (2012) Wtip and Vangl2 are required for mitotic spindle orientation and cloaca morphogenesis. Biol Open 1 588-96 PubMed GONUTS page
  24. 24.0 24.1 24.2 Zhao, C & Malicki, J (2011) Nephrocystins and MKS proteins interact with IFT particle and facilitate transport of selected ciliary cargos. EMBO J. 30 2532-44 PubMed GONUTS page
  25. Walsh, GS et al. (2011) Planar polarity pathway and Nance-Horan syndrome-like 1b have essential cell-autonomous functions in neuronal migration. Development 138 3033-42 PubMed GONUTS page
  26. 26.0 26.1 Burcklé, C et al. (2011) Control of the Wnt pathways by nephrocystin-4 is required for morphogenesis of the zebrafish pronephros. Hum. Mol. Genet. 20 2611-27 PubMed GONUTS page
  27. 27.0 27.1 Dohn, MR et al. (2013) Planar cell polarity proteins differentially regulate extracellular matrix organization and assembly during zebrafish gastrulation. Dev. Biol. 383 39-51 PubMed GONUTS page
  28. 28.0 28.1 Young, T et al. (2014) The PDZ domain protein Mcc is a novel effector of non-canonical Wnt signaling during convergence and extension in zebrafish. Development 141 3505-16 PubMed GONUTS page
  29. 29.0 29.1 Li, S et al. (2011) Rack1 is required for Vangl2 membrane localization and planar cell polarity signaling while attenuating canonical Wnt activity. Proc. Natl. Acad. Sci. U.S.A. 108 2264-9 PubMed GONUTS page
  30. 30.0 30.1 30.2 30.3 30.4 30.5 30.6 30.7 30.8 30.9 May-Simera, HL et al. (2010) Bbs8, together with the planar cell polarity protein Vangl2, is required to establish left-right asymmetry in zebrafish. Dev. Biol. 345 215-25 PubMed GONUTS page
  31. 31.0 31.1 Borovina, A et al. (2010) Vangl2 directs the posterior tilting and asymmetric localization of motile primary cilia. Nat. Cell Biol. 12 407-12 PubMed GONUTS page
  32. Vervenne, HB et al. (2008) Lpp is involved in Wnt/PCP signaling and acts together with Scrib to mediate convergence and extension movements during zebrafish gastrulation. Dev. Biol. 320 267-77 PubMed GONUTS page
  33. 33.0 33.1 Ferrante, MI et al. (2009) Convergent extension movements and ciliary function are mediated by ofd1, a zebrafish orthologue of the human oral-facial-digital type 1 syndrome gene. Hum. Mol. Genet. 18 289-303 PubMed GONUTS page
  34. 34.0 34.1 34.2 Li, X et al. (2013) Gpr125 modulates Dishevelled distribution and planar cell polarity signaling. Development 140 3028-39 PubMed GONUTS page
  35. Sittaramane, V et al. (2013) The PCP protein Vangl2 regulates migration of hindbrain motor neurons by acting in floor plate cells, and independently of cilia function. Dev. Biol. 382 400-12 PubMed GONUTS page