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DANRE:Q9IAT0

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Species (Taxon ID) Danio rerio (Zebrafish) (Brachydanio rerio). (7955)
Gene Name(s) No Information Provided. (synonyms: zic2 (ECO:0000313 with EMBL:AAF73190.1))
Protein Name(s) Uncharacterized protein (ECO:0000313 with Ensembl:ENSDARP00000026131)

Zic family member 2 (Odd-paired homolog, Drosophila), a (ECO:0000313 with EMBL:AAH65635.1) Zinc finger cerebellum 2 protein (ECO:0000313 with EMBL:AAF73190.1)

External Links
UniProt Q9IAT0
EMBL BX469902
AF151535
BC065635
RefSeq NP_571633.1
UniGene Dr.76889
SMR Q9IAT0
STRING 7955.ENSDARP00000026131
Ensembl ENSDART00000010774
GeneID 58077
KEGG dre:58077
CTD 58077
ZFIN ZDB-GENE-000710-4
eggNOG COG5048
GeneTree ENSGT00760000118771
HOGENOM HOG000232057
HOVERGEN HBG007135
KO K06235
OMA DSAHMGA
OrthoDB EOG76472R
PhylomeDB Q9IAT0
TreeFam TF351425
NextBio 20892337
PRO PR:Q9IAT0
Proteomes UP000000437
GO GO:0046872
GO:0003676
GO:0021846
GO:0033278
GO:0021536
GO:0009953
GO:0060059
GO:0048703
GO:0030901
GO:0045892
GO:0014032
GO:0001841
GO:0042127
GO:0008589
Gene3D 3.30.160.60
InterPro IPR007087
IPR015880
IPR013087
Pfam PF00096
SMART SM00355
PROSITE PS00028
PS50157

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001841

neural tube formation

PMID:19470582[1]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-MRPHLNO-070522-3
ZFIN:ZDB-MRPHLNO-070523-1

P

Seeded From UniProt

complete

GO:0003676

nucleic acid binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR013087

F

Seeded From UniProt

complete

GO:0008589

regulation of smoothened signaling pathway

PMID:19855021[2]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-070522-3

P

Seeded From UniProt

complete

GO:0009953

dorsal/ventral pattern formation

PMID:18248235[3]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-GENO-060811-12

P

Seeded From UniProt

complete

GO:0009953

dorsal/ventral pattern formation

PMID:18248235[3]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0014032

neural crest cell development

PMID:23665173[4]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-070522-3

P

Seeded From UniProt

complete

GO:0021536

diencephalon development

PMID:18358464[5]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-GENO-070406-1
ZFIN:ZDB-MRPHLNO-070522-3

P

Seeded From UniProt

complete

GO:0021536

diencephalon development

PMID:18358464[5]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-GENO-080605-1
ZFIN:ZDB-MRPHLNO-070522-3

P

Seeded From UniProt

complete

GO:0021536

diencephalon development

PMID:18358464[5]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-070522-3

P

Seeded From UniProt

complete

GO:0021846

cell proliferation in forebrain

PMID:18358464[5]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-070522-3

P

Seeded From UniProt

complete

GO:0030901

midbrain development

PMID:17215296[6]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-070522-3

P

Seeded From UniProt

complete

GO:0030901

midbrain development

PMID:19470582[1]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-MRPHLNO-070522-3
ZFIN:ZDB-MRPHLNO-070523-1

P

Seeded From UniProt

complete

GO:0030902

hindbrain development

PMID:23937294[7]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-MRPHLNO-070522-3
ZFIN:ZDB-MRPHLNO-130809-1

P

Seeded From UniProt

complete

GO:0033278

cell proliferation in midbrain

PMID:17215296[6]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-070522-3

P

Seeded From UniProt

complete

GO:0042127

regulation of cell proliferation

PMID:17215296[6]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-070522-3

P

Seeded From UniProt

complete

GO:0045892

negative regulation of transcription, DNA-templated

PMID:19855021[2]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-070522-3

P

Seeded From UniProt

complete

GO:0046872

metal ion binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR007087

F

Seeded From UniProt

complete

GO:0048385

regulation of retinoic acid receptor signaling pathway

PMID:23937294[7]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-MRPHLNO-070522-3
ZFIN:ZDB-MRPHLNO-130809-1

P

Seeded From UniProt

complete

GO:0048703

embryonic viscerocranium morphogenesis

PMID:23665173[4]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-070522-3

P

Seeded From UniProt

complete

GO:0060059

embryonic retina morphogenesis in camera-type eye

PMID:17215296[6]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-070522-3

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Nyholm, MK et al. (2009) A novel genetic mechanism regulates dorsolateral hinge-point formation during zebrafish cranial neurulation. J. Cell. Sci. 122 2137-48 PubMed GONUTS page
  2. 2.0 2.1 Sanek, NA et al. (2009) Zebrafish zic2a patterns the forebrain through modulation of Hedgehog-activated gene expression. Development 136 3791-800 PubMed GONUTS page
  3. 3.0 3.1 Dodou, E et al. (2004) Ventralized zebrafish embryo rescue by overexpression of Zic2a. Zebrafish 1 239-56 PubMed GONUTS page
  4. 4.0 4.1 Teslaa, JJ et al. (2013) Zebrafish Zic2a and Zic2b regulate neural crest and craniofacial development. Dev. Biol. 380 73-86 PubMed GONUTS page
  5. 5.0 5.1 5.2 5.3 Sanek, NA & Grinblat, Y (2008) A novel role for zebrafish zic2a during forebrain development. Dev. Biol. 317 325-35 PubMed GONUTS page
  6. 6.0 6.1 6.2 6.3 Nyholm, MK et al. (2007) The zebrafish zic2a-zic5 gene pair acts downstream of canonical Wnt signaling to control cell proliferation in the developing tectum. Development 134 735-46 PubMed GONUTS page
  7. 7.0 7.1 Drummond, DL et al. (2013) The role of Zic transcription factors in regulating hindbrain retinoic acid signaling. BMC Dev. Biol. 13 31 PubMed GONUTS page