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DANRE:Q4ZJE9
Contents
Species (Taxon ID) | Danio rerio (Zebrafish) (Brachydanio rerio). (7955) | |
Gene Name(s) | jun (ECO:0000313 with ZFIN:ZDB-GENE-030131-7859) | |
Protein Name(s) | C-Jun (ECO:0000313 with EMBL:AAY21257.1) | |
External Links | ||
UniProt | Q4ZJE9 | |
EMBL | DQ003340 | |
UniGene | Dr.1064 | |
ProteinModelPortal | Q4ZJE9 | |
SMR | Q4ZJE9 | |
STRING | 7955.ENSDARP00000063911 | |
PaxDb | Q4ZJE9 | |
ZFIN | ZDB-GENE-030131-7859 | |
eggNOG | KOG0837 ENOG410XRWH | |
HOGENOM | HOG000006648 | |
HOVERGEN | HBG001722 | |
GO | GO:0000790 GO:0005667 GO:0000978 GO:0000981 GO:0003713 GO:0008134 GO:0060070 GO:0032870 GO:0000122 GO:0045597 GO:0045944 GO:0051726 GO:0010941 GO:0042127 GO:0046686 GO:0051591 GO:0034097 GO:0042493 GO:0032496 GO:0009612 GO:0051597 GO:0009314 GO:0006351 | |
Gene3D | 1.10.880.10 | |
InterPro | IPR004827 IPR015558 IPR005643 IPR002112 IPR008917 | |
PANTHER | PTHR11462:SF8 | |
Pfam | PF00170 PF03957 | |
PRINTS | PR00043 | |
SMART | SM00338 | |
SUPFAM | SSF47454 | |
PROSITE | PS50217 PS00036 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
GO:0022004 |
midbrain-hindbrain boundary maturation during brain development |
ECO:0000315 |
P |
Loss of c-Jun rescued the deformed brain induced by trim69 knockdown shown in figure |
complete | |||||
GO:0022004 |
midbrain-hindbrain boundary maturation during brain development |
ECO:0000315 |
P |
Loss of c-Jun rescued the deformed brain induced by trim69 knockdown shown in figure 7 |
complete | |||||
GO:0072089 |
stem cell proliferation |
ECO:0000314 |
P |
qPCR showed the expression for stem cell markers can be rescued by co-injection with c-Jun-MO and this match with the in situ hybridization shown in figure 3 |
complete | |||||
involved_in |
GO:0060070 |
canonical Wnt signaling pathway |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
ZFIN:ZDB-MRPHLNO-080908-1 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0051597 |
response to methylmercury |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0046686 |
response to cadmium ion |
ECO:0000270 |
expression pattern evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
contributes_to |
GO:0008013 |
beta-catenin binding |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
ZFIN:ZDB-MRPHLNO-080908-1 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0007420 |
brain development |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
ZFIN:ZDB-MRPHLNO-080908-1 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0005667 |
transcription factor complex |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
ZFIN:ZDB-MRPHLNO-080908-1 |
C |
Seeded From UniProt |
complete | ||
contributes_to |
GO:0003700 |
DNA-binding transcription factor activity |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
ZFIN:ZDB-MRPHLNO-080908-1 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0051726 |
regulation of cell cycle |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:96646 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0051591 |
response to cAMP |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000894785 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0045944 |
positive regulation of transcription by RNA polymerase II |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0001291 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0045597 |
positive regulation of cell differentiation |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:96647 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0042493 |
response to drug |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:96646 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0034097 |
response to cytokine |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000894785 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0032870 |
cellular response to hormone stimulus |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000894785 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0032496 |
response to lipopolysaccharide |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000894785 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0010033 |
response to organic substance |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000894784 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0009612 |
response to mechanical stimulus |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000894785 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0009314 |
response to radiation |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000894785 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0008134 |
transcription factor binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:96648 |
F |
Seeded From UniProt |
complete | ||
part_of |
GO:0005667 |
transcription factor complex |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0001291 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005654 |
nucleoplasm |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000894784 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0003713 |
transcription coactivator activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000894785 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0000981 |
DNA-binding transcription factor activity, RNA polymerase II-specific |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0001291 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0000978 |
RNA polymerase II proximal promoter sequence-specific DNA binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:96647 |
F |
Seeded From UniProt |
complete | ||
part_of |
GO:0000790 |
nuclear chromatin |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000894784 |
C |
Seeded From UniProt |
complete | ||
involved_in |
GO:0000122 |
negative regulation of transcription by RNA polymerase II |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000894784 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0003677 |
DNA binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0003700 |
DNA-binding transcription factor activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006355 |
regulation of transcription, DNA-templated |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR002112 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0003677 |
DNA binding |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 Han, R et al. (2016) Trim69 regulates zebrafish brain development by ap-1 pathway. Sci Rep 6 24034 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 Gan, XQ et al. (2008) Nuclear Dvl, c-Jun, beta-catenin, and TCF form a complex leading to stabilization of beta-catenin-TCF interaction. J. Cell Biol. 180 1087-100 PubMed GONUTS page
- ↑ Gonzalez, P et al. (2005) Comparative effects of dietary methylmercury on gene expression in liver, skeletal muscle, and brain of the zebrafish (Danio rerio). Environ. Sci. Technol. 39 3972-80 PubMed GONUTS page
- ↑ Gonzalez, P et al. (2006) Comparative effects of direct cadmium contamination on gene expression in gills, liver, skeletal muscles and brain of the zebrafish (Danio rerio). Biometals 19 225-35 PubMed GONUTS page
- ↑ 5.00 5.01 5.02 5.03 5.04 5.05 5.06 5.07 5.08 5.09 5.10 5.11 5.12 5.13 5.14 5.15 5.16 5.17 5.18 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
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- GO:0051726 ! regulation of cell cycle
- GO:0006355 ! regulation of DNA-templated transcription
- GO:0051597 ! response to methylmercury
- GO:0046686 ! response to cadmium ion
- GO:0051591 ! response to cAMP
- GO:0009612 ! response to mechanical stimulus
- GO:0009314 ! response to radiation
- GO:0034097 ! response to cytokine
- GO:0032496 ! response to lipopolysaccharide
- GO:0042493 ! response to drug
- GO:0000978 ! RNA polymerase II cis-regulatory region sequence-specific DNA binding
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