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DANRE:Q1LUT2

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Species (Taxon ID) Danio rerio (Zebrafish) (Brachydanio rerio). (7955)
Gene Name(s) No Information Provided.
Protein Name(s) DNA topoisomerase 2 (ECO:0000256 with RuleBase:RU000381)
External Links
UniProt Q1LUT2
EMBL BX927238
CR391921
RefSeq NP_001038656.1
UniGene Dr.105756
ProteinModelPortal Q1LUT2
SMR Q1LUT2
Ensembl ENSDART00000130695
GeneID 569877
KEGG dre:569877
CTD 7155
ZFIN ZDB-GENE-041008-136
GeneTree ENSGT00390000016222
HOGENOM HOG000216693
HOVERGEN HBG052998
InParanoid Q1LUT2
KO K03164
OMA CHPPKIT
OrthoDB EOG73JKTM
PhylomeDB Q1LUT2
TreeFam TF105282
NextBio 20889886
PRO PR:Q1LUT2
Proteomes UP000000437
GO GO:0009330
GO:0005634
GO:0005524
GO:0008301
GO:0003918
GO:0006200
GO:0007412
GO:0006265
GO:0006268
GO:0044774
GO:0006312
GO:0000712
GO:0010842
GO:0031290
GO:0000819
Gene3D 1.10.268.10
3.30.1360.40
3.30.230.10
3.30.565.10
3.40.50.670
3.90.199.10
InterPro IPR024946
IPR012542
IPR003594
IPR020568
IPR014721
IPR028467
IPR001241
IPR002205
IPR013758
IPR013757
IPR013506
IPR013759
IPR013760
IPR018522
IPR006171
PANTHER PTHR10169:SF36
Pfam PF00204
PF00521
PF08070
PF02518
PF01751
PRINTS PR00418
SMART SM00387
SM00433
SM00434
SUPFAM SSF54211
SSF55874
SSF56719
PROSITE PS00177
PS50880

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000166

nucleotide binding

GO_REF:0000038

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

GO:0000712

resolution of meiotic recombination intermediates

GO_REF:0000033

IBA: Inferred from Biological aspect of Ancestor

PANTHER:PTN000018888

P

Seeded From UniProt

complete

GO:0000819

sister chromatid segregation

GO_REF:0000033

IBA: Inferred from Biological aspect of Ancestor

PANTHER:PTN000018888

P

Seeded From UniProt

complete

GO:0003677

DNA binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001154
InterPro:IPR001241
InterPro:IPR002205
InterPro:IPR012542
InterPro:IPR013506
InterPro:IPR013757
InterPro:IPR013758
InterPro:IPR013759
InterPro:IPR018522

F

Seeded From UniProt

complete

GO:0003677

DNA binding

GO_REF:0000038

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0238

F

Seeded From UniProt

complete

GO:0003916

DNA topoisomerase activity

GO_REF:0000038

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0799

F

Seeded From UniProt

complete

GO:0003918

DNA topoisomerase type II (ATP-hydrolyzing) activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001154
InterPro:IPR001241
InterPro:IPR002205
InterPro:IPR012542
InterPro:IPR013506
InterPro:IPR013757
InterPro:IPR013758
InterPro:IPR013759
InterPro:IPR013760
InterPro:IPR018522
InterPro:IPR028467

F

Seeded From UniProt

complete

GO:0003918

DNA topoisomerase type II (ATP-hydrolyzing) activity

GO_REF:0000003

IEA: Inferred from Electronic Annotation

EC:5.99.1.3

F

Seeded From UniProt

complete

GO:0003918

DNA topoisomerase type II (ATP-hydrolyzing) activity

GO_REF:0000033

IBA: Inferred from Biological aspect of Ancestor

PANTHER:PTN000018846

F

Seeded From UniProt

complete

GO:0005524

ATP binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001154
InterPro:IPR001241
InterPro:IPR002205
InterPro:IPR012542
InterPro:IPR013506
InterPro:IPR013757
InterPro:IPR013758
InterPro:IPR013759
InterPro:IPR013760
InterPro:IPR018522

F

Seeded From UniProt

complete

GO:0005524

ATP binding

GO_REF:0000038

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0067

F

Seeded From UniProt

complete

GO:0005634

nucleus

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR012542

C

Seeded From UniProt

complete

GO:0005634

nucleus

GO_REF:0000033

IBA: Inferred from Biological aspect of Ancestor

PANTHER:PTN000018888

C

Seeded From UniProt

complete

GO:0006259

DNA metabolic process

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR013758

P

Seeded From UniProt

complete

GO:0006265

DNA topological change

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001154
InterPro:IPR001241
InterPro:IPR002205
InterPro:IPR013506
InterPro:IPR013757
InterPro:IPR013758
InterPro:IPR013759
InterPro:IPR018522
InterPro:IPR028467

P

Seeded From UniProt

complete

GO:0006265

DNA topological change

GO_REF:0000033

IBA: Inferred from Biological aspect of Ancestor

PANTHER:PTN000018846

P

Seeded From UniProt

complete

GO:0006268

DNA unwinding involved in DNA replication

GO_REF:0000033

IBA: Inferred from Biological aspect of Ancestor

PANTHER:PTN000018846

P

Seeded From UniProt

complete

GO:0007412

axon target recognition

PMID:21610027[1]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-110729-5

P

Seeded From UniProt

complete

GO:0008301

DNA binding, bending

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR028467

F

Seeded From UniProt

complete

GO:0009330

DNA topoisomerase complex (ATP-hydrolyzing)

GO_REF:0000033

IBA: Inferred from Biological aspect of Ancestor

PANTHER:PTN000018846

C

Seeded From UniProt

complete

GO:0010842

retina layer formation

PMID:21610027[1]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-110729-5

P

Seeded From UniProt

complete

GO:0016853

isomerase activity

GO_REF:0000038

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0413

F

Seeded From UniProt

complete

GO:0031290

retinal ganglion cell axon guidance

PMID:21610027[1]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-110729-5

P

Seeded From UniProt

complete

GO:0044774

mitotic DNA integrity checkpoint

GO_REF:0000033

IBA: Inferred from Biological aspect of Ancestor

PANTHER:PTN000018888

P

Seeded From UniProt

complete

NOT

GO:0009295

nucleoid

GO_REF:0000033

IBA: Inferred from Biological aspect of Ancestor

PANTHER:PTN000018888

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 Nevin, LM et al. (2011) Topoisomerase IIbeta is required for lamina-specific targeting of retinal ganglion cell axons and dendrites. Development 138 2457-65 PubMed GONUTS page