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DANRE:PESC

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Species (Taxon ID) Danio rerio (Zebrafish) (Brachydanio rerio). (7955)
Gene Name(s) pes
Protein Name(s) Pescadillo
External Links
UniProt P79741
EMBL U77627
BX470167
CU459127
CU459127
BX470167
AB046115
BC049339
BC160624
RefSeq NP_571105.2
UniGene Dr.191
ProteinModelPortal P79741
SMR P79741
STRING 7955.ENSDARP00000026992
Ensembl ENSDART00000023101
GeneID 30228
KEGG dre:30228
CTD 30228
ZFIN ZDB-GENE-990415-206
eggNOG COG5163
GeneTree ENSGT00390000002626
HOGENOM HOG000006022
HOVERGEN HBG023409
InParanoid P79741
KO K14843
OMA YDKIMFG
OrthoDB EOG7X9G6N
PhylomeDB P79741
TreeFam TF300671
NextBio 20806685
PRO PR:P79741
Proteomes UP000000437
Bgee P79741
GO GO:0005730
GO:0005654
GO:0070545
GO:0030687
GO:0043021
GO:0008283
GO:0031017
GO:0000466
GO:0000463
GO:0048709
GO:0051726
Gene3D 3.40.50.10190
HAMAP MF_03028
InterPro IPR001357
IPR010613
Pfam PF00533
PF06732
SMART SM00292
SUPFAM SSF52113
PROSITE PS50172

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0032502

developmental process

PMID:8985183[1]

ECO:0000315

P

Fig. 9

complete
CACAO 3724

GO:0014003

oligodendrocyte development

PMID:22384214[2]

ECO:0000315

P

Figure 2a & 2b. Loss of Pescadillo results in loss of dorsal oligodendrocytes

complete
CACAO 3904

GO:0000084

S phase of mitotic cell cycle

PMID:22384214[2]

ECO:0000315

P

Figure 5b & 5c. Loss of pes function cells stayed in S phase

complete
CACAO 3905

part_of

GO:0070545

PeBoW complex

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:O00541

C

Seeded From UniProt

complete

part_of

GO:0030687

preribosome, large subunit precursor

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:O00541

C

Seeded From UniProt

complete

involved_in

GO:0008283

cell population proliferation

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:O00541

P

Seeded From UniProt

complete

part_of

GO:0005730

nucleolus

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:O00541

C

Seeded From UniProt

complete

part_of

GO:0005654

nucleoplasm

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:O00541

C

Seeded From UniProt

complete

involved_in

GO:0000466

maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:O00541

P

Seeded From UniProt

complete

involved_in

GO:0000463

maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:O00541

P

Seeded From UniProt

complete

involved_in

GO:0051726

regulation of cell cycle

PMID:22384214[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

ZFIN:ZDB-GENO-120330-4

P

Seeded From UniProt

complete

involved_in

GO:0048709

oligodendrocyte differentiation

PMID:22384214[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

ZFIN:ZDB-GENO-120330-4

P

Seeded From UniProt

complete

involved_in

GO:0031017

exocrine pancreas development

PMID:22872088[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

ZFIN:ZDB-MRPHLNO-120817-3

P

Seeded From UniProt

complete

part_of

GO:0070545

PeBoW complex

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1890613
PANTHER:PTN000259535
SGD:S000003335
UniProtKB:O00541

C

Seeded From UniProt

complete

involved_in

GO:0000463

maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1890613
PANTHER:PTN000259535
UniProtKB:O00541

P

Seeded From UniProt

complete

part_of

GO:0005730

nucleolus

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR010613

C

Seeded From UniProt

complete

involved_in

GO:0042254

ribosome biogenesis

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR010613

P

Seeded From UniProt

complete

involved_in

GO:0000466

maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000107540

P

Seeded From UniProt

complete

involved_in

GO:0000463

maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000107540

P

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000107540

C

Seeded From UniProt

complete

part_of

GO:0005730

nucleolus

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000107540

C

Seeded From UniProt

complete

involved_in

GO:0042273

ribosomal large subunit biogenesis

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000107540

P

Seeded From UniProt

complete

enables

GO:0043021

ribonucleoprotein complex binding

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000107540

F

Seeded From UniProt

complete

part_of

GO:0030687

preribosome, large subunit precursor

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000107540

C

Seeded From UniProt

complete

involved_in

GO:0006364

rRNA processing

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0698

P

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539

C

Seeded From UniProt

complete

involved_in

GO:0042254

ribosome biogenesis

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0690

P

Seeded From UniProt

complete

part_of

GO:0005654

nucleoplasm

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0190

C

Seeded From UniProt

complete

part_of

GO:0005730

nucleolus

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0188

C

Seeded From UniProt

complete

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Notes

References

See Help:References for how to manage references in GONUTS.

  1. ↑ Allende, ML et al. (1996) Insertional mutagenesis in zebrafish identifies two novel genes, pescadillo and dead eye, essential for embryonic development. Genes Dev. 10 3141-55 PubMed GONUTS page
  2. ↑ 2.0 2.1 2.2 2.3 Simmons, T & Appel, B (2012) Mutation of pescadillo disrupts oligodendrocyte formation in zebrafish. PLoS ONE 7 e32317 PubMed GONUTS page
  3. ↑ Provost, E et al. (2012) Ribosomal biogenesis genes play an essential and p53-independent role in zebrafish pancreas development. Development 139 3232-41 PubMed GONUTS page
  4. ↑ 4.0 4.1 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
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