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This is your chance to make annotations OR challenge other team's annotations. You may also DEFEND or suggest improvements to your own annotations IF they have been challenged. Please note, although we ENCOURAGE challenges, an excess of identical challenges that do not appear to be applicable to the annotation or well thought out will be considered spam and ignored.

It is now the 4th OPEN Period for CACAO Phage Hunters 2018! It will end on Sunday April 22, 2018 at 11:59 pm CDT
This is your chance to make annotations OR challenge other team's annotations. You may also DEFEND or suggest improvements to your own annotations IF they have been challenged. Please note, although we ENCOURAGE challenges, an excess of identical challenges that do not appear to be applicable to the annotation or well thought out will be considered spam and ignored.

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DANRE:F1QX69

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Species (Taxon ID) Danio rerio (Zebrafish) (Brachydanio rerio). (7955)
Gene Name(s) No Information Provided.
Protein Name(s) Uncharacterized protein (ECO:0000313 with Ensembl:ENSDARP00000113959)
External Links
UniProt F1QX69
EMBL CT033825
ProteinModelPortal F1QX69
Ensembl ENSDART00000139933
ZFIN ZDB-GENE-030219-1
GeneTree ENSGT00740000114888
InParanoid F1QX69
OMA FDHIGWD
OrthoDB EOG7DFXD1
TreeFam TF351786
Proteomes UP000000437
GO GO:0005576
GO:0035462
GO:0003140
GO:0007368
GO:0035469
GO:0035050
GO:0040007
GO:0003146
GO:0001947
GO:0048368
GO:2000223
Gene3D 2.10.90.10
InterPro IPR029034
IPR002405
IPR001839
IPR001111
IPR015615
IPR017948
PANTHER PTHR11848
Pfam PF00019
PF00688
PRINTS PR00669
SMART SM00204
SUPFAM SSF57501
PROSITE PS00250
PS51362

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001947

heart looping

PMID:12702646[1]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-060112-1

P

Seeded From UniProt

complete

GO:0003140

determination of left/right asymmetry in lateral mesoderm

PMID:12702646[1]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-060112-1

P

Seeded From UniProt

complete

GO:0003140

determination of left/right asymmetry in lateral mesoderm

PMID:12702646[1]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-060112-2

P

Seeded From UniProt

complete

GO:0003140

determination of left/right asymmetry in lateral mesoderm

PMID:15084459[2]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-MRPHLNO-060112-1
ZFIN:ZDB-MRPHLNO-060718-1

P

Seeded From UniProt

complete

GO:0003146

heart jogging

PMID:18784369[3]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-090225-2

P

Seeded From UniProt

complete

GO:0005125

cytokine activity

GO_REF:0000033

IBA: Inferred from Biological aspect of Ancestor

PANTHER:PTN000218063

F

Seeded From UniProt

complete

GO:0005160

transforming growth factor beta receptor binding

GO_REF:0000033

IBA: Inferred from Biological aspect of Ancestor

PANTHER:PTN000218063

F

Seeded From UniProt

complete

GO:0005576

extracellular region

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002405

C

Seeded From UniProt

complete

GO:0005576

extracellular region

GO_REF:0000038

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0964

C

Seeded From UniProt

complete

GO:0005615

extracellular space

GO_REF:0000033

IBA: Inferred from Biological aspect of Ancestor

PANTHER:PTN000218063

C

Seeded From UniProt

complete

GO:0007368

determination of left/right symmetry

PMID:14576439[4]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0007368

determination of left/right symmetry

PMID:16207761[5]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-060112-2

P

Seeded From UniProt

complete

GO:0007368

determination of left/right symmetry

PMID:17592620[6]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-060112-2

P

Seeded From UniProt

complete

GO:0007368

determination of left/right symmetry

PMID:17678853[7]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-060112-1

P

Seeded From UniProt

complete

GO:0007368

determination of left/right symmetry

PMID:18267096[8]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-060112-1
ZFIN:ZDB-MRPHLNO-060112-2

P

Seeded From UniProt

complete

GO:0007368

determination of left/right symmetry

PMID:18784369[3]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-090225-2

P

Seeded From UniProt

complete

GO:0008083

growth factor activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001111
InterPro:IPR001839
InterPro:IPR017948

F

Seeded From UniProt

complete

GO:0008083

growth factor activity

GO_REF:0000038

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0339

F

Seeded From UniProt

complete

GO:0010862

positive regulation of pathway-restricted SMAD protein phosphorylation

GO_REF:0000033

IBA: Inferred from Biological aspect of Ancestor

PANTHER:PTN000218063

P

Seeded From UniProt

complete

GO:0035050

embryonic heart tube development

PMID:18267096[8]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-060112-1
ZFIN:ZDB-MRPHLNO-060112-2

P

Seeded From UniProt

complete

GO:0035462

determination of left/right asymmetry in diencephalon

PMID:12702646[1]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-060112-1

P

Seeded From UniProt

complete

GO:0035462

determination of left/right asymmetry in diencephalon

PMID:12702646[1]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-060112-2

P

Seeded From UniProt

complete

GO:0035462

determination of left/right asymmetry in diencephalon

PMID:19363156[9]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-060112-1

P

Seeded From UniProt

complete

GO:0035469

determination of pancreatic left/right asymmetry

PMID:12702646[1]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-060112-1

P

Seeded From UniProt

complete

GO:0035469

determination of pancreatic left/right asymmetry

PMID:12702646[1]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-060112-2

P

Seeded From UniProt

complete

GO:0040007

growth

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001111

P

Seeded From UniProt

complete

GO:0042981

regulation of apoptotic process

GO_REF:0000033

IBA: Inferred from Biological aspect of Ancestor

PANTHER:PTN000218063

P

Seeded From UniProt

complete

GO:0043408

regulation of MAPK cascade

GO_REF:0000033

IBA: Inferred from Biological aspect of Ancestor

PANTHER:PTN000218063

P

Seeded From UniProt

complete

GO:0048368

lateral mesoderm development

PMID:18985756[10]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-060112-1

P

Seeded From UniProt

complete

GO:0048468

cell development

GO_REF:0000033

IBA: Inferred from Biological aspect of Ancestor

PANTHER:PTN000218063

P

Seeded From UniProt

complete

GO:0060395

SMAD protein signal transduction

GO_REF:0000033

IBA: Inferred from Biological aspect of Ancestor

PANTHER:PTN000218063

P

Seeded From UniProt

complete

GO:0070698

type I activin receptor binding

GO_REF:0000033

IBA: Inferred from Biological aspect of Ancestor

PANTHER:PTN000218109

F

Seeded From UniProt

complete

GO:2000223

regulation of BMP signaling pathway involved in heart jogging

PMID:12702646[1]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-060112-1

P

Seeded From UniProt

complete

GO:2000223

regulation of BMP signaling pathway involved in heart jogging

PMID:12702646[1]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-060112-2

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 Long, S et al. (2003) The zebrafish nodal-related gene southpaw is required for visceral and diencephalic left-right asymmetry. Development 130 2303-16 PubMed GONUTS page
  2. Hashimoto, H et al. (2004) The Cerberus/Dan-family protein Charon is a negative regulator of Nodal signaling during left-right patterning in zebrafish. Development 131 1741-53 PubMed GONUTS page
  3. 3.0 3.1 Baker, K et al. (2008) Direct and indirect roles for Nodal signaling in two axis conversions during asymmetric morphogenesis of the zebrafish heart. Proc. Natl. Acad. Sci. U.S.A. 105 13924-9 PubMed GONUTS page
  4. Horne-Badovinac, S et al. (2003) A cellular framework for gut-looping morphogenesis in zebrafish. Science 302 662-5 PubMed GONUTS page
  5. Gamse, JT et al. (2005) Directional asymmetry of the zebrafish epithalamus guides dorsoventral innervation of the midbrain target. Development 132 4869-81 PubMed GONUTS page
  6. Kuan, YS et al. (2007) Selective asymmetry in a conserved forebrain to midbrain projection. J. Exp. Zool. B Mol. Dev. Evol. 308 669-78 PubMed GONUTS page
  7. Carl, M et al. (2007) Wnt/Axin1/beta-catenin signaling regulates asymmetric nodal activation, elaboration, and concordance of CNS asymmetries. Neuron 55 393-405 PubMed GONUTS page
  8. 8.0 8.1 Smith, KA et al. (2008) Rotation and asymmetric development of the zebrafish heart requires directed migration of cardiac progenitor cells. Dev. Cell 14 287-97 PubMed GONUTS page
  9. Roussigné, M et al. (2009) Nodal signalling imposes left-right asymmetry upon neurogenesis in the habenular nuclei. Development 136 1549-57 PubMed GONUTS page
  10. Wang, X & Yost, HJ (2008) Initiation and propagation of posterior to anterior (PA) waves in zebrafish left-right development. Dev. Dyn. 237 3640-7 PubMed GONUTS page