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DANRE:DVR1

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Species (Taxon ID) Danio rerio (Zebrafish) (Brachydanio rerio). (7955)
Gene Name(s) dvr1 (synonyms: dvr-1, vg1)
Protein Name(s) Protein DVR-1
External Links
UniProt P35621
EMBL U00931
RefSeq NP_571023.1
UniGene Dr.307
ProteinModelPortal P35621
SMR P35621
STRING 7955.ENSDARP00000055378
PRIDE P35621
Ensembl ENSDART00000055379
GeneID 30125
KEGG dre:30125
CTD 9573
ZFIN ZDB-GENE-980526-389
eggNOG NOG255568
GeneTree ENSGT00760000118883
HOGENOM HOG000249476
HOVERGEN HBG004860
InParanoid P35621
KO K05495
OMA KDVGWQD
OrthoDB EOG71CFMF
TreeFam TF351789
Reactome REACT_208506
NextBio 20806604
Proteomes UP000000437
Bgee P35621
GO GO:0005576
GO:0040007
GO:0051781
Gene3D 2.10.90.10
InterPro IPR029034
IPR001839
IPR001111
IPR015615
IPR017948
PANTHER PTHR11848
Pfam PF00019
PF00688
SMART SM00204
SUPFAM SSF57501
PROSITE PS00250
PS51362

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:1904136

regulation of convergent extension involved in notochord morphogenesis

PMID:24892953[1]

IGI: Inferred from Genetic Interaction

UniProtKB:Q06ZW3


P

In Figure 2 G-I, injection of Setdb2 morpholino will result in a wider and shorter notochord, however, when Dvr1 morpholino is co-injected with Setdb2 morpholino, the effects of setdb2 morpholino are reversed.

complete
CACAO 10544

GO:1904103

regulation of convergent extension involved in gastrulation

PMID:24892953[1]

IGI: Inferred from Genetic Interaction

UniProtKB:Q06ZW3


P

In Figure 2 G-I injection of Setdb2 morpholino will result in a wider and shorter notochord, however, when Dvr1 morpholino is co-injected with Setdb2 morpholino, the effects of setdb2 morpholino are reversed.

complete
CACAO 10670

GO:1904086

regulation of epiboly involved in gastrulation with mouth forming second

PMID:24892953[1]

IMP: Inferred from Mutant Phenotype

P

In Figure 3 A-F, varying amounts of dvr1 mRNA are injected into embryos and compared to a control embryo. With larger amounts of dvr1 mRNA injection there are higher percentages of delayed epiboly, leading to the conclusion that dvr1 is involved in epiboly.

complete
CACAO 10672

GO:1904130

regulation of convergent extension involved in neural plate elongation

PMID:24892953[1]

IMP: Inferred from Mutant Phenotype

P

In figure 3 J and K, embryos injected with 10pg of DVR1 mRNA show broader neural plates than embryos not injected. This suggests involvement in neural plate morphogenesis.

complete
CACAO 10714

GO:1904127

regulation of convergent extension involved in somitogenesis

PMID:24892953[1]

IMP: Inferred from Mutant Phenotype

P

In figure 3 L and M, embryos injected with 10pg of DVR1 mRNA show wider and slightly shorter somites than embryos not injected. This suggests involvement in somitogenesis.

complete
CACAO 10715

GO:0005576

extracellular region

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0964

C

Seeded From UniProt

complete

GO:0005576

extracellular region

GO_REF:0000039

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0243

C

Seeded From UniProt

complete

GO:0008083

growth factor activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001111
InterPro:IPR001839
InterPro:IPR017948

F

Seeded From UniProt

complete

GO:0008083

growth factor activity

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0339

F

Seeded From UniProt

complete

GO:0040007

growth

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001111

P

Seeded From UniProt

complete

GO:0051781

positive regulation of cell division

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0497

P

Seeded From UniProt

complete

GO:1904086

regulation of epiboly involved in gastrulation with mouth forming second

PMID:24892953[1]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 1.5 Du, TT et al. (2014) Setdb2 controls convergence and extension movements during zebrafish gastrulation by transcriptional regulation of dvr1. Dev. Biol. 392 233-44 PubMed GONUTS page