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Category:GO:1990666 ! PCSK9-LDLR complex
name: PCSK9-LDLR complex
namespace: cellular_component
def: "A protein complex consisting of the serine protease PCSK9 (proprotein convertase subtilisin/kexin-9) and a low-density lipoprotein receptor (LDLR). Interaction typically occurs through the epidermal growth factor-like repeat A (EGF-A) domain of the LDLR, and complex formation promotes degradation of the LDLR through the endosome/lysosome pathway." [GOC:BHF, GOC:nc, PMID:18250299, PMID:24440079]
synonym: "PCSK9.LDLR complex" EXACT [PMID:18799458]
synonym: "PCSK9/LDL-R complex" EXACT [PMID:24440079]
synonym: "PCSK9:EGF-A complex" RELATED [PMID:18250299]
synonym: "PCSK9:low-density lipoprotein receptor complex" EXACT [GOC:bf]
is_a: GO:0032991 ! protein-containing complex
AmiGO
<GOterm>GO:1990666</GOterm>
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Pages in category "GO:1990666 ! PCSK9-LDLR complex"
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