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Category:GO:0070772 ! PAS complex
name: PAS complex
namespace: cellular_component
def: "A class III phosphatidylinositol 3-kinase complex that contains a phosphatidylinositol-3-phosphate 5-kinase subunit (Fab1p in yeast; PIKfyve in mammals), a kinase activator, and a phosphatase, and may also contain additional proteins; it is involved in regulating the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate. In mammals the complex is composed of PIKFYVE, FIG4 and VAC14. In yeast it is composed of Atg18p, Fig4p, Fab1p, Vac14p and Vac7p." [PMID:18950639, PMID:19037259, PMID:19158662]
synonym: "autophagy-specific phosphatidylinositol 3-kinase complex" RELATED [PMID:24165940]
is_a: GO:0035032 ! phosphatidylinositol 3-kinase complex, class III
relationship: part_of: GO:0005774 ! vacuolar membrane
AmiGO
<GOterm>GO:0070772</GOterm>
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