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Category:GO:0070581 ! rolling circle DNA replication
name: rolling circle DNA replication
namespace: biological_process
def: "A DNA-dependent DNA replication process in which a single-stranded DNA molecule is synthesized from a circular duplex template. Replication typically does not cease when one circumference has been replicated, but continues around the circumference several more times, producing a long single strand comprising multimers of the replicon." [GOC:cb, GOC:mah, ISBN:0198506732]
synonym: "rolling circle replication" EXACT [GOC:cb]
is_a: GO:0006261 ! DNA-templated DNA replication
AmiGO
<GOterm>GO:0070581</GOterm>
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Usage Notes
- This method of DNA replication is commonly referred to as sigma replication
About rolling circle replication in viruses
This is a PROCESS term, so use this term for proteins that are shown to be involved in replicating the DNA genome of a virus.
- Some viruses use both theta replication to initiate genome replication and then successive rounds of rolling circle (sigma) replication, such as bacteriophage lambda [1] or Herpes virus (see [2] for a review)
- RCR (rolling circle replication) is the method used by bacteriophage phiX174 [3] [4] and plant viruses such as the geminiviruses [5] to replicate their ssDNA genomes.
- It may be possible, depending on the evidence in a scientific article, that you will have to use a less specific term. Consider:
Other suggested terms that might be suitable if you are looking at modes of DNA replication
- If you are looking for MOLECULAR FUNCTION (ACTIVITY) terms that correspond with this process, you might consider starting here:
- If you are looking for CELLULAR COMPONENT (COMPLEX) terms that correspond with this process, you might consider starting here:
More information on virus from ViralZone
- For more information on ssDNA viruses, see Viral Zone ssDNA virus list
- For more information on dsDNA viruses, see Viral Zone dsDNA virus list
References
See Help:References for how to manage references in GONUTS.
- ↑ Konopa, G et al. (2000) Bacteriophage and host mutants causing the rolling-circle lambda DNA replication early after infection. FEBS Lett. 472 217-20 PubMed GONUTS page
- ↑ Boehmer, PE & Lehman, IR (1997) Herpes simplex virus DNA replication. Annu. Rev. Biochem. 66 347-84 PubMed GONUTS page
- ↑ van der Ende, A et al. (1982) Initiation and termination of the bacteriophage phi X174 rolling circle DNA replication in vivo: packaging of plasmid single-stranded DNA into bacteriophage phi X174 coats. Nucleic Acids Res. 10 6849-63 PubMed GONUTS page
- ↑ Dressler, D (1970) The rolling circle for phiX DNA replication. II. Synthesis of single-stranded circles. Proc. Natl. Acad. Sci. U.S.A. 67 1934-42 PubMed GONUTS page
- ↑ Koonin, EV & Ilyina, TV (1992) Geminivirus replication proteins are related to prokaryotic plasmid rolling circle DNA replication initiator proteins. J. Gen. Virol. 73 ( Pt 10) 2763-6 PubMed GONUTS page
Pages in category "GO:0070581 ! rolling circle DNA replication"
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