Category:GO:0050983 ! obsolete deoxyhypusine biosynthetic process from spermidine

This GO term has been obsoleted. Do not annotate to it.

id: GO:0050983
name: obsolete deoxyhypusine biosynthetic process from spermidine
namespace: biological_process
def: "OBSOLETE. The chemical reactions resulting in the formation of deoxyhypusine from spermidine by the enzyme [eIF-5A]-deoxyhypusine synthase. The reaction occurs in four steps: 1. spermidine + NAD+ = dehydrospermidine + NADH + H+; 2. dehydrospermidine + [enzyme]-lysine = 1,3-diaminopropane + [enzyme]-lysine-N6=CH(CH2)3NH2; 3. [enzyme]-lysine-N6=CH(CH2)3NH2 = [eIF-5A]-lysine-N6=CH(CH2)3NH2; 4. [eIF-5A]-lysine-N6=CH(CH2)3NH2 + NADH + H+ = [eIF-5A]-deoxyhypusine + NAD+." [MetaCyc:1.1.1.249-RXN]
comment: The reason for obsoletion is that although GO:0050983 is described as a multistep process, the entire reaction is carried out by a single enzyme, therefore was replacey by the molecular function GO:0034038 deoxyhypusine synthase activity.
synonym: "deoxyhypusine anabolism from spermidine, using deoxyhypusine synthase" EXACT []
synonym: "deoxyhypusine biosynthesis from spermidine, using deoxyhypusine synthase" EXACT []
synonym: "deoxyhypusine biosynthetic process from spermidine, using deoxyhypusine synthase" EXACT []
synonym: "deoxyhypusine formation from spermidine, using deoxyhypusine synthase" EXACT []
synonym: "spermidine breakdown to deoxyhypusine, using deoxyhypusine synthase" EXACT []
synonym: "spermidine catabolic process to deoxyhypusine, using deoxyhypusine synthase" EXACT []
synonym: "spermidine degradation to deoxyhypusine, using deoxyhypusine synthase" EXACT []
is_obsolete: true
consider: GO:0034038 ! deoxyhypusine synthase activity

AmiGO <GOterm>GO:0050983</GOterm>
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