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Category:GO:0036398 ! TCR signalosome
name: TCR signalosome
namespace: cellular_component
def: "A multi-protein complex containing at least the T-cell receptor complex and the LAT (linker for activation of T cells) scaffold protein. Also contains a variety of signaling proteins including co-receptors, kinases, phosphatases and adaptors such as CD8. Connects events on the plasma membrane to distal signaling cascades to ultimately modulate T cell biology." [GOC:krc, PMID:17534068, PMID:20107804, PMID:22426112]
synonym: "LAT signalosome" EXACT [GOC:krc, PMID:17534068]
synonym: "linker for activation of T cells signalosome" EXACT [PMID:17534068]
is_a: GO:0032991 ! protein-containing complex
relationship: has_part: GO:0042101 ! T cell receptor complex
AmiGO
<GOterm>GO:0036398</GOterm>
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