Category:GO:0033897 ! ribonuclease T2 activity

name: ribonuclease T2 activity
namespace: molecular_function
def: "Catalysis of the reaction: a ribonucleotidyl-ribonucleotide-RNA + H2O = a 3'-end 3'-phospho-ribonucleotide-RNA + a 5'-end dephospho-ribonucleoside-RNA + H+. This reaction is a two-stage endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides with 2',3'-cyclic phosphate intermediates." [EC:4.6.1.19, RHEA:68052]
synonym: "acid ribonuclease activity" EXACT []
synonym: "acid RNase activity" EXACT []
synonym: "base-non-specific ribonuclease activity" EXACT []
synonym: "Escherichia coli ribonuclease I' ribonuclease PP2 activity" EXACT []
synonym: "Escherichia coli ribonuclease II activity" RELATED [EC:4.6.1.19]
synonym: "non-base specific ribonuclease activity" EXACT []
synonym: "nonbase-specific RNase activity" EXACT []
synonym: "nonspecific RNase activity" EXACT []
synonym: "ribonnuclease (non-base specific) activity" EXACT []
synonym: "ribonuclease (non-base specific) activity" RELATED []
synonym: "ribonuclease II activity" BROAD [EC:4.6.1.19]
synonym: "ribonuclease M activity" EXACT []
synonym: "ribonuclease N2 activity" EXACT []
synonym: "ribonuclease PP3 activity" RELATED []
synonym: "ribonuclease U4 activity" EXACT []
synonym: "ribonucleate 3'-oligonucleotide hydrolase activity" EXACT []
synonym: "ribonucleate nucleotido-2'-transferase (cyclizing) activity" BROAD []
synonym: "RNAase CL activity" EXACT []
synonym: "RNase (non-base specific) activity" EXACT []
synonym: "RNase II activity" BROAD [EC:4.6.1.19]
synonym: "RNase M activity" RELATED []
synonym: "RNase Ms activity" EXACT []
synonym: "RNase T2 activity" RELATED [EC:4.6.1.19]
xref: EC:4.6.1.19
xref: MetaCyc:3.1.27.5-RXN
xref: RHEA:68052
is_a: GO:0004521 ! RNA endonuclease activity
is_a: GO:0016849 ! phosphorus-oxygen lyase activity

AmiGO <GOterm>GO:0033897</GOterm>
Gene Ontology Home