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Category:GO:0009380 ! excinuclease repair complex
name: excinuclease repair complex
namespace: cellular_component
def: "Any of the protein complexes formed by the UvrABC excinuclease system, which carries out nucleotide excision repair. Three different complexes are formed by the 3 proteins as they proceed through the excision repair process. First a complex consisting of two A subunits and two B subunits bind DNA and unwind it around the damaged site. Then, the A subunits disassociate leaving behind a stable complex between B subunits and DNA. Now, subunit C binds to this B+DNA complex and causes subunit B to nick the DNA on one side of the complex while subunit C nicks the DNA on the other side of the complex. DNA polymerase I and DNA ligase can then repair the resulting gap." [GOC:mah, GOC:mlg, PMID:12145219, PMID:15192705]
synonym: "excinuclease ABC complex" EXACT []
synonym: "UvrABC excinuclease complex" EXACT []
is_a: GO:1905347 ! endodeoxyribonuclease complex
is_a: GO:1990391 ! DNA repair complex
AmiGO
<GOterm>GO:0009380</GOterm>
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