GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
ECOLI:UVRC
Contents
Species (Taxon ID) | Escherichia coli (strain K12). (83333) | |
Gene Name(s) | uvrC | |
Protein Name(s) | UvrABC system protein C
Protein UvrC Excinuclease ABC subunit C | |
External Links | ||
UniProt | P0A8G0 | |
EMBL | X03691 U00096 AP009048 M24615 X05398 M12299 | |
PIR | F64954 | |
RefSeq | NP_416423.4 YP_490170.1 | |
PDB | 1KFT | |
PDBsum | 1KFT | |
ProteinModelPortal | P0A8G0 | |
SMR | P0A8G0 | |
DIP | DIP-47875N | |
IntAct | P0A8G0 | |
MINT | MINT-1221235 | |
STRING | 511145.b1913 | |
PaxDb | P0A8G0 | |
PRIDE | P0A8G0 | |
EnsemblBacteria | AAC74980 BAA15733 | |
GeneID | 12931385 947203 | |
KEGG | ecj:Y75_p1884 eco:b1913 | |
PATRIC | 32119159 | |
EchoBASE | EB1056 | |
EcoGene | EG11063 | |
eggNOG | COG0322 | |
HOGENOM | HOG000279961 | |
InParanoid | P0A8G0 | |
KO | K03703 | |
OMA | RCPGVCQ | |
OrthoDB | EOG6K13R9 | |
PhylomeDB | P0A8G0 | |
BioCyc | EcoCyc:EG11063-MONOMER ECOL316407:JW1898-MONOMER MetaCyc:EG11063-MONOMER | |
EvolutionaryTrace | P0A8G0 | |
PRO | PR:P0A8G0 | |
Proteomes | UP000000318 UP000000625 | |
Genevestigator | P0A8G0 | |
GO | GO:0005737 GO:0009380 GO:0003677 GO:0009381 GO:0006289 GO:0009432 | |
Gene3D | 3.40.1440.10 4.10.860.10 | |
HAMAP | MF_00203 | |
InterPro | IPR027299 IPR000305 IPR000445 IPR003583 IPR010994 IPR001943 IPR004791 IPR001162 | |
Pfam | PF01541 PF00633 PF02151 PF08459 | |
SMART | SM00465 SM00278 | |
SUPFAM | SSF46600 SSF47781 SSF82771 | |
TIGRFAMs | TIGR00194 | |
PROSITE | PS50164 PS50151 PS50165 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
GO:0006289 |
nucleotide-excision repair |
ECO:0000315 |
P |
Fig2, show mutations in His,Asp,Glu residues in catalytic domain affects ability to make a 5' incision |
complete | |||||
part_of |
GO:0009380 |
excinuclease repair complex |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0009380 |
excinuclease repair complex |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG11063 |
C |
Seeded From UniProt |
complete | ||
involved_in |
GO:0006974 |
cellular response to DNA damage stimulus |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG13993 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0009314 |
response to radiation |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0090305 |
nucleic acid phosphodiester bond hydrolysis |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0004518 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0003677 |
DNA binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006281 |
DNA repair |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006289 |
nucleotide-excision repair |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0009380 |
excinuclease repair complex |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0009381 |
excinuclease ABC activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0003677 |
DNA binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000163512 |
F |
Seeded From UniProt |
complete | ||
part_of |
GO:0005737 |
cytoplasm |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000163512 |
C |
Seeded From UniProt |
complete | ||
involved_in |
GO:0009432 |
SOS response |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000163512 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0006289 |
nucleotide-excision repair |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000163512 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0009381 |
excinuclease ABC activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000163512 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0006281 |
DNA repair |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000163512 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006281 |
DNA repair |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006974 |
cellular response to DNA damage stimulus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0009432 |
SOS response |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0004518 |
nuclease activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Lin, JJ & Sancar, A (1992) Active site of (A)BC excinuclease. I. Evidence for 5' incision by UvrC through a catalytic site involving Asp399, Asp438, Asp466, and His538 residues. J. Biol. Chem. 267 17688-92 PubMed GONUTS page
- ↑ Verhoeven, EE et al. (2002) The presence of two UvrB subunits in the UvrAB complex ensures damage detection in both DNA strands. EMBO J. 21 4196-205 PubMed GONUTS page
- ↑ 3.0 3.1 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ Sargentini, NJ et al. () Screen for genes involved in radiation survival of Escherichia coli and construction of a reference database. Mutat. Res. 793-794 1-14 PubMed GONUTS page