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Category:GO:0008384 ! IkappaB kinase activity

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DAG for GO:0008384id: GO:0008384

name: IkappaB kinase activity
namespace: molecular_function
def: "Catalysis of the reaction: ATP + IkappaB protein = ADP + IkappaB phosphoprotein." [EC:2.7.11.10]
comment: Note that phosphorylation of IkappaB targets it for proteasomal degradation and allows the nuclear translocation of kB.
synonym: "ATP:IkappaB protein phosphotransferase activity" EXACT [EC:2.7.11.10]
synonym: "CHUK" RELATED [EC:2.7.11.10]
synonym: "ikappaB kinase activity" EXACT [EC:2.7.11.10]
synonym: "IKBKA" RELATED [EC:2.7.11.10]
synonym: "IKBKB" RELATED [EC:2.7.11.10]
synonym: "IKK" RELATED [EC:2.7.11.10]
synonym: "IKK-1" RELATED [EC:2.7.11.10]
synonym: "IKK-2" RELATED [EC:2.7.11.10]
synonym: "inhibitor of NF-kappaB kinase activity" EXACT [EC:2.7.11.10]
synonym: "inhibitor of NFkappaB kinase activity" EXACT [EC:2.7.11.10]
synonym: "STK12" RELATED [EC:2.7.11.10]
synonym: "TANK-binding kinase 1 activity" NARROW [EC:2.7.11.10]
synonym: "TBK1" RELATED [EC:2.7.11.10]
xref: EC:2.7.11.10
xref: MetaCyc:2.7.11.10-RXN
is_a: GO:0004674 ! protein serine/threonine kinase activity
is_a: GO:0004871 ! signal transducer activity
relationship: part_of: GO:0007252 ! I-kappaB phosphorylation

AmiGO

Last version checked
releases/2017-02-26.

23:02:2017 10:01.

slaulederkind
Last updated
releases/2016-09-27

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Pages in category "GO:0008384 ! IkappaB kinase activity"

The following 15 pages are in this category, out of 15 total.


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