name: mitochondrial permeability transition pore complex
def: "A protein complex that connects the inner and outer membranes of animal mitochondria and acts as a pore that can open transiently to allow free diffusion of solutes between the mitochondrial matrix and the cytosol. The pore complex is formed of the voltage-dependent anion channel (VDAC), the adenine nucleotide translocase (ANT) and cyclophilin-D (CyP-D)." [PMID:10393078]
synonym: "mitochondrial PT pore complex" EXACT 
synonym: "MPTP complex" EXACT 
synonym: "PTPC" BROAD [PMID:21760595]
is_a: GO:0046930 ! pore complex
is_a: GO:0098798 ! mitochondrial protein complex
relationship: part_of: GO:0005740 ! mitochondrial envelope
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