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CHICK:Q5ZMJ0

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) PPIF (ECO:0000313 with Ensembl:ENSGALP00000007666)
Protein Name(s) Peptidyl-prolyl cis-trans isomerase (ECO:0000256 with RuleBase:RU000493)
External Links
UniProt Q5ZMJ0
EMBL AADN03005135
AJ719394
RefSeq NP_001026397.1
UniGene Gga.1727
SMR Q5ZMJ0
STRING 9031.ENSGALP00000007666
Ensembl ENSGALT00000007678
GeneID 423723
KEGG gga:423723
CTD 10105
eggNOG COG0652
GeneTree ENSGT00760000119119
HOGENOM HOG000065981
HOVERGEN HBG001065
KO K09565
OMA DVGADNQ
OrthoDB EOG79GT7W
PhylomeDB Q5ZMJ0
TreeFam TF312801
NextBio 20826150
PRO PR:Q5ZMJ0
Proteomes UP000000539
GO GO:0005739
GO:0003755
GO:0008637
GO:0071243
GO:0071277
GO:0070301
GO:0070266
GO:0032780
GO:2001243
GO:0090324
GO:2000276
GO:0090201
GO:0090200
GO:0006457
GO:1902445
GO:0010939
GO:0010849
GO:0002931
Gene3D 2.40.100.10
InterPro IPR029000
IPR024936
IPR020892
IPR002130
Pfam PF00160
PIRSF PIRSF001467
PRINTS PR00153
SUPFAM SSF50891
PROSITE PS00170
PS50072

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:1902445

regulation of mitochondrial membrane permeability involved in programmed necrotic cell death

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:2145814
PANTHER:PTN002594555
UniProtKB:P30405

P

Seeded From UniProt

complete

involved_in

GO:0070301

cellular response to hydrogen peroxide

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:2145814
PANTHER:PTN002594555
UniProtKB:P30405

P

Seeded From UniProt

complete

enables

GO:0051082

unfolded protein binding

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002594282
SGD:S000003793
SGD:S000004206

F

Seeded From UniProt

complete

involved_in

GO:0046902

regulation of mitochondrial membrane permeability

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:2145814
PANTHER:PTN002594555
RGD:628670
UniProtKB:P30405

P

Seeded From UniProt

complete

involved_in

GO:0042026

protein refolding

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002594282
SGD:S000003793
SGD:S000004206

P

Seeded From UniProt

complete

enables

GO:0016018

cyclosporin A binding

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0002936
PANTHER:PTN002594282
RGD:1303174
RGD:3372
RGD:628670
SGD:S000002562
UniProtKB:O43447
UniProtKB:P21568
UniProtKB:P21569
UniProtKB:P23284
UniProtKB:P30405
UniProtKB:P30414
UniProtKB:P45877
UniProtKB:P62937
UniProtKB:Q08752
UniProtKB:Q13427
UniProtKB:Q76NN7
UniProtKB:Q9UNP9

F

Seeded From UniProt

complete

part_of

GO:0005739

mitochondrion

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002594555
RGD:628670
UniProtKB:P30405

C

Seeded From UniProt

complete

enables

GO:0003755

peptidyl-prolyl cis-trans isomerase activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0039581
MGI:MGI:97751
PANTHER:PTN002594282
PomBase:SPAC1B3.03c
PomBase:SPBC1709.04c
PomBase:SPBC28F2.03
PomBase:SPBP8B7.25
RGD:1303174
RGD:620315
RGD:628670
SGD:S000001099
SGD:S000002562
SGD:S000003793
SGD:S000004206
SGD:S000004543
TAIR:locus:2045663
TAIR:locus:2179822
UniProtKB:O43447
UniProtKB:P21568
UniProtKB:P21569
UniProtKB:P23284
UniProtKB:P24367
UniProtKB:P30405
UniProtKB:P30414
UniProtKB:P34791
UniProtKB:P45877
UniProtKB:P62937
UniProtKB:Q08752
UniProtKB:Q13427
UniProtKB:Q76NN7
UniProtKB:Q9UNP9
WB:WBGene00000879
WB:WBGene00000881
WB:WBGene00000884

F

Seeded From UniProt

complete

enables

GO:0003755

peptidyl-prolyl cis-trans isomerase activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0039581
MGI:MGI:97751
PANTHER:PTN002594282
PomBase:SPAC1B3.03c
PomBase:SPBC1709.04c
PomBase:SPBC28F2.03
PomBase:SPBP8B7.25
RGD:1303174
RGD:620315
RGD:628670
SGD:S000001099
SGD:S000002562
SGD:S000003793
SGD:S000004206
SGD:S000004543
TAIR:locus:2045663
TAIR:locus:2179822
UniProtKB:O43447
UniProtKB:P21568
UniProtKB:P21569
UniProtKB:P23284
UniProtKB:P24367
UniProtKB:P30405
UniProtKB:P30414
UniProtKB:P34791
UniProtKB:P45877
UniProtKB:P62937
UniProtKB:Q08752
UniProtKB:Q13427
UniProtKB:Q76NN7
UniProtKB:Q8IXY8
UniProtKB:Q9UNP9
WB:WBGene00000879
WB:WBGene00000881
WB:WBGene00000884

F

Seeded From UniProt

complete

involved_in

GO:2001243

negative regulation of intrinsic apoptotic signaling pathway

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P30405
ensembl:ENSP00000225174

P

Seeded From UniProt

complete

involved_in

GO:1902686

mitochondrial outer membrane permeabilization involved in programmed cell death

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P30405
ensembl:ENSP00000225174

P

Seeded From UniProt

complete

involved_in

GO:1902445

regulation of mitochondrial membrane permeability involved in programmed necrotic cell death

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P30405
ensembl:ENSP00000225174

P

Seeded From UniProt

complete

involved_in

GO:0090201

negative regulation of release of cytochrome c from mitochondria

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P30405
ensembl:ENSP00000225174

P

Seeded From UniProt

complete

involved_in

GO:0070301

cellular response to hydrogen peroxide

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P30405
ensembl:ENSP00000225174

P

Seeded From UniProt

complete

involved_in

GO:0046902

regulation of mitochondrial membrane permeability

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P30405
ensembl:ENSP00000225174

P

Seeded From UniProt

complete

involved_in

GO:0043066

negative regulation of apoptotic process

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P30405
ensembl:ENSP00000225174

P

Seeded From UniProt

complete

enables

GO:0016018

cyclosporin A binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P30405
ensembl:ENSP00000225174

F

Seeded From UniProt

complete

part_of

GO:0005757

mitochondrial permeability transition pore complex

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P30405
ensembl:ENSP00000225174

C

Seeded From UniProt

complete

part_of

GO:0005739

mitochondrion

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P30405
ensembl:ENSP00000225174

C

Seeded From UniProt

complete

enables

GO:0003755

peptidyl-prolyl cis-trans isomerase activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P30405
ensembl:ENSP00000225174

F

Seeded From UniProt

complete

involved_in

GO:0000413

protein peptidyl-prolyl isomerization

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P30405
ensembl:ENSP00000225174

P

Seeded From UniProt

complete

involved_in

GO:2000276

negative regulation of oxidative phosphorylation uncoupler activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q99KR7
ensembl:ENSMUSP00000022419

P

Seeded From UniProt

complete

involved_in

GO:1902445

regulation of mitochondrial membrane permeability involved in programmed necrotic cell death

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q99KR7
ensembl:ENSMUSP00000022419

P

Seeded From UniProt

complete

involved_in

GO:0090324

negative regulation of oxidative phosphorylation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q99KR7
ensembl:ENSMUSP00000022419

P

Seeded From UniProt

complete

involved_in

GO:0090200

positive regulation of release of cytochrome c from mitochondria

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q99KR7
ensembl:ENSMUSP00000022419

P

Seeded From UniProt

complete

involved_in

GO:0071277

cellular response to calcium ion

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q99KR7
ensembl:ENSMUSP00000022419

P

Seeded From UniProt

complete

involved_in

GO:0071243

cellular response to arsenic-containing substance

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q99KR7
ensembl:ENSMUSP00000022419

P

Seeded From UniProt

complete

involved_in

GO:0070301

cellular response to hydrogen peroxide

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q99KR7
ensembl:ENSMUSP00000022419

P

Seeded From UniProt

complete

involved_in

GO:0070266

necroptotic process

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q99KR7
ensembl:ENSMUSP00000022419

P

Seeded From UniProt

complete

involved_in

GO:0046902

regulation of mitochondrial membrane permeability

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q99KR7
ensembl:ENSMUSP00000022419

P

Seeded From UniProt

complete

involved_in

GO:0032780

negative regulation of ATPase activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q99KR7
ensembl:ENSMUSP00000022419

P

Seeded From UniProt

complete

involved_in

GO:0010939

regulation of necrotic cell death

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q99KR7
ensembl:ENSMUSP00000022419

P

Seeded From UniProt

complete

involved_in

GO:0010849

regulation of proton-transporting ATPase activity, rotational mechanism

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q99KR7
ensembl:ENSMUSP00000022419

P

Seeded From UniProt

complete

involved_in

GO:0008637

apoptotic mitochondrial changes

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q99KR7
ensembl:ENSMUSP00000022419

P

Seeded From UniProt

complete

involved_in

GO:0006979

response to oxidative stress

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q99KR7
ensembl:ENSMUSP00000022419

P

Seeded From UniProt

complete

involved_in

GO:0002931

response to ischemia

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q99KR7
ensembl:ENSMUSP00000022419

P

Seeded From UniProt

complete

part_of

GO:0005739

mitochondrion

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:A0A024QZS4
ensembl:ENSP00000225174

C

Seeded From UniProt

complete

involved_in

GO:0000413

protein peptidyl-prolyl isomerization

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002130

P

Seeded From UniProt

complete

enables

GO:0003755

peptidyl-prolyl cis-trans isomerase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002130
InterPro:IPR020892
InterPro:IPR024936

F

Seeded From UniProt

complete

involved_in

GO:0006457

protein folding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR020892

P

Seeded From UniProt

complete

enables

GO:0003755

peptidyl-prolyl cis-trans isomerase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:5.2.1.8

F

Seeded From UniProt

complete

enables

GO:0016853

isomerase activity

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0413

F

Seeded From UniProt

complete

enables

GO:0003755

peptidyl-prolyl cis-trans isomerase activity

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0697

F

Seeded From UniProt

complete

enables

GO:0003755

peptidyl-prolyl cis-trans isomerase activity

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000248790

F

Seeded From UniProt

complete

edit table

Notes

References

See Help:References for how to manage references in GONUTS.

  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
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