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Category:GO:0004512 ! inositol-3-phosphate synthase activity
name: inositol-3-phosphate synthase activity
namespace: molecular_function
def: "Catalysis of the reaction: D-glucose 6-phosphate = 1D-myo-inositol 3-phosphate. This reaction requires NAD, which dehydrogenates the CHOH group to CO at C-5 of the glucose 6-phosphate, making C-6 into an active methylene, able to condense with the aldehyde at C-1. Finally, the enzyme-bound NADH reconverts C-5 into the CHOH form." [EC:5.5.1.4, RHEA:10716]
synonym: "1L-myo-inositol-1-phosphate lyase (isomerizing)" RELATED [EC:5.5.1.4]
synonym: "D-glucose 6-phosphate cycloaldolase activity" RELATED [EC:5.5.1.4]
synonym: "glucocycloaldolase activity" RELATED [EC:5.5.1.4]
synonym: "glucose 6-phosphate cyclase activity" RELATED [EC:5.5.1.4]
synonym: "glucose-6-phosphate inositol monophosphate cycloaldolase activity" RELATED [EC:5.5.1.4]
synonym: "inositol 1-phosphate synthatase activity" RELATED [EC:5.5.1.4]
synonym: "inositol 1-phosphate synthetase activity" RELATED [EC:5.5.1.4]
xref: EC:5.5.1.4
xref: KEGG_REACTION:R07324
xref: MetaCyc:MYO-INOSITOL-1-PHOSPHATE-SYNTHASE-RXN
xref: RHEA:10716
is_a: GO:0016872 ! intramolecular lyase activity
AmiGO
<GOterm>GO:0004512</GOterm>
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