HUMAN:INO1

Species (Taxon ID)	Homo sapiens (Human). (9606)
Gene Name(s)	ISYNA1 (synonyms: INO1)
Protein Name(s)	Inositol-3-phosphate synthase 1 IPS 1 Myo-inositol 1-phosphate synthase MI-1-P synthase MIP synthase hIPS Myo-inositol 1-phosphate synthase A1 hINO1
External Links
UniProt	Q9NPH2
EMBL	AF207640 AF220530 AF220259 AF220250 AF220251 AF220252 AF220253 AF220254 AF220255 AF220256 AF220257 AF220258 AF086921 AK001325 AK021526 AK092179 AL137749 AC008397 CH471106 CH471106 BC004320 BC018952 BC066902
CCDS	CCDS12379.1 CCDS54234.1 CCDS62603.1
PIR	T46317
RefSeq	NP_001164409.1 NP_001240318.1 NP_057452.1
UniGene	Hs.405873
ProteinModelPortal	Q9NPH2
SMR	Q9NPH2
BioGrid	119562
IntAct	Q9NPH2
MINT	MINT-4942504
STRING	9606.ENSP00000315147
PhosphoSite	Q9NPH2
DMDM	74734304
REPRODUCTION-2DPAGE	IPI00549569
MaxQB	Q9NPH2
PaxDb	Q9NPH2
PRIDE	Q9NPH2
DNASU	51477
Ensembl	ENST00000338128 ENST00000457269 ENST00000578963
GeneID	51477
KEGG	hsa:51477
UCSC	uc002nja.2 uc002nje.2
CTD	51477
GeneCards	GC19M018545
HGNC	HGNC:29821
HPA	CAB020720 HPA007931 HPA008232
MIM	611670
neXtProt	NX_Q9NPH2
PharmGKB	PA164721116
eggNOG	COG1260
GeneTree	ENSGT00390000018395
HOVERGEN	HBG061200
InParanoid	Q9NPH2
KO	K01858
OMA	NPVLYAP
OrthoDB	EOG74J97N
PhylomeDB	Q9NPH2
TreeFam	TF300382
Reactome	REACT_150352
UniPathway	UPA00823
ChiTaRS	ISYNA1
GenomeRNAi	51477
NextBio	55121
PRO	PR:Q9NPH2
Proteomes	UP000005640
Bgee	Q9NPH2
CleanEx	HS_ISYNA1
ExpressionAtlas	Q9NPH2
Genevestigator	Q9NPH2
GO	GO:0005829 GO:0004512 GO:0006021 GO:0043647 GO:0008654 GO:0044281
Gene3D	3.40.50.720
InterPro	IPR002587 IPR013021 IPR016040
PANTHER	PTHR11510
Pfam	PF01658 PF07994
PIRSF	PIRSF015578

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0004512	inositol-3-phosphate synthase activity	PMID:23902760	ECO:0000315			F		Figure 8C shows the effect of point mutations on the activity of the inositol-3-phosphate synthase. The assay measured the inorganic phosphate liberated from glucose 6-phosphate which is dependent on the activity of the synthase enzyme.	complete CACAO 10037
enables	GO:0004512	inositol-3-phosphate synthase activity	PMID:23902760	ECO:0000315	mutant phenotype evidence used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0006021	inositol biosynthetic process		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000161823 SGD:S000003689 TAIR:locus:2135297 UniProtKB:Q8I3Y8 dictyBase:DDB_G0285505	P		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000161823 TAIR:locus:2135297 TAIR:locus:2184153 UniProtKB:Q38862	C		Seeded From UniProt	complete
enables	GO:0004512	inositol-3-phosphate synthase activity		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0025885 PANTHER:PTN000161823 SGD:S000003689 TAIR:locus:2135297 TAIR:locus:2184153 UniProtKB:Q38862 UniProtKB:Q8I3Y8 UniProtKB:Q9NPH2 dictyBase:DDB_G0285505	F		Seeded From UniProt	complete
enables	GO:0004512	inositol-3-phosphate synthase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002587	F		Seeded From UniProt	complete
involved_in	GO:0006021	inositol biosynthetic process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002587	P		Seeded From UniProt	complete
involved_in	GO:0008654	phospholipid biosynthetic process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002587	P		Seeded From UniProt	complete
enables	GO:0004512	inositol-3-phosphate synthase activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:5.5.1.4	F		Seeded From UniProt	complete
involved_in	GO:0043647	inositol phosphate metabolic process	Reactome:R-HSA-1855183	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005829	cytosol	Reactome:R-HSA-1855178	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0963 UniProtKB-SubCell:SL-0086	C		Seeded From UniProt	complete
involved_in	GO:0006629	lipid metabolic process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0443	P		Seeded From UniProt	complete
involved_in	GO:0006021	inositol biosynthetic process	GO_REF:0000037 GO_REF:0000041	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0398 UniPathway:UPA00823	P		Seeded From UniProt	complete
enables	GO:0016853	isomerase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0413	F		Seeded From UniProt	complete
involved_in	GO:0008654	phospholipid biosynthetic process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0594	P		Seeded From UniProt	complete
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References

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