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Category:GO:0004421 ! hydroxymethylglutaryl-CoA synthase activity

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DAG for GO:0004421id: GO:0004421

name: hydroxymethylglutaryl-CoA synthase activity
namespace: molecular_function
def: "Catalysis of the reaction: acetoacetyl-CoA + acetyl-CoA + H2O = (S)-3-hydroxy-3-methylglutaryl-CoA + CoA + H+." [RHEA:10188]
comment: Note that this function was formerly EC:4.1.3.5.
synonym: "(s)-3-hydroxy-3-methylglutaryl-CoA acetoacetyl-CoA-lyase (CoA- acetylating) activity" RELATED [EC:2.3.3.10]
synonym: "(S)-3-hydroxy-3-methylglutaryl-CoA acetoacetyl-CoA-lyase (CoA-acetylating)" RELATED [EC:2.3.3.10]
synonym: "3-hydroxy-3-methylglutaryl CoA synthetase activity" RELATED [EC:2.3.3.10]
synonym: "3-hydroxy-3-methylglutaryl coenzyme A synthase activity" RELATED [EC:2.3.3.10]
synonym: "3-hydroxy-3-methylglutaryl coenzyme A synthetase activity" RELATED [EC:2.3.3.10]
synonym: "3-hydroxy-3-methylglutaryl-CoA synthase activity" RELATED [EC:2.3.3.10]
synonym: "3-hydroxy-3-methylglutaryl-coenzyme A synthase activity" RELATED [EC:2.3.3.10]
synonym: "acetoacetyl coenzyme A transacetase activity" RELATED [EC:2.3.3.10]
synonym: "acetyl-CoA:acetoacetyl-CoA C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming)" RELATED [EC:2.3.3.10]
synonym: "beta-hydroxy-beta-methylglutaryl-CoA synthase activity" RELATED [EC:2.3.3.10]
synonym: "HMG-CoA synthase activity" RELATED [EC:2.3.3.10]
synonym: "hydroxymethylglutaryl coenzyme A synthase activity" RELATED [EC:2.3.3.10]
synonym: "hydroxymethylglutaryl coenzyme A-condensing enzyme" RELATED [EC:2.3.3.10]
synonym: "hydroxymethylglutaryl coenzyme alpha-condensing enzyme activity" RELATED [EC:2.3.3.10]
xref: EC:2.3.3.10
xref: KEGG_REACTION:R01978
xref: MetaCyc:HYDROXYMETHYLGLUTARYL-COA-SYNTHASE-RXN
xref: RHEA:10188
is_a: GO:0046912 ! acyltransferase activity, acyl groups converted into alkyl on transfer

AmiGO <GOterm>GO:0004421</GOterm>
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Pages in category "GO:0004421 ! hydroxymethylglutaryl-CoA synthase activity"

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