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Category:GO:0004421 ! hydroxymethylglutaryl-CoA synthase activity

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DAG for GO:0004421id: GO:0004421

name: hydroxymethylglutaryl-CoA synthase activity
namespace: molecular_function
def: "Catalysis of the reaction: acetoacetyl-CoA + acetyl-CoA + H(2)O = (S)-3-hydroxy-3-methylglutaryl-CoA + CoA + H(+)." [EC:2.3.3.10, RHEA:10191]
comment: Note that this function was formerly EC:4.1.3.5.
subset: gosubset_prok
synonym: "(s)-3-hydroxy-3-methylglutaryl-CoA acetoacetyl-CoA-lyase (CoA- acetylating) activity" EXACT [EC:2.3.3.10]
synonym: "(S)-3-hydroxy-3-methylglutaryl-CoA acetoacetyl-CoA-lyase (CoA-acetylating)" EXACT [EC:2.3.3.10]
synonym: "3-hydroxy-3-methylglutaryl CoA synthetase activity" EXACT [EC:2.3.3.10]
synonym: "3-hydroxy-3-methylglutaryl coenzyme A synthase activity" EXACT [EC:2.3.3.10]
synonym: "3-hydroxy-3-methylglutaryl coenzyme A synthetase activity" EXACT [EC:2.3.3.10]
synonym: "3-hydroxy-3-methylglutaryl-CoA synthase activity" EXACT [EC:2.3.3.10]
synonym: "3-hydroxy-3-methylglutaryl-coenzyme A synthase activity" EXACT [EC:2.3.3.10]
synonym: "acetoacetyl coenzyme A transacetase activity" EXACT [EC:2.3.3.10]
synonym: "acetyl-CoA:acetoacetyl-CoA C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming)" EXACT [EC:2.3.3.10]
synonym: "beta-hydroxy-beta-methylglutaryl-CoA synthase activity" EXACT [EC:2.3.3.10]
synonym: "HMG-CoA synthase activity" EXACT [EC:2.3.3.10]
synonym: "hydroxymethylglutaryl coenzyme A synthase activity" EXACT [EC:2.3.3.10]
synonym: "hydroxymethylglutaryl coenzyme A-condensing enzyme" RELATED [EC:2.3.3.10]
synonym: "hydroxymethylglutaryl coenzyme alpha-condensing enzyme activity" EXACT [EC:2.3.3.10]
xref: EC:2.3.3.10
xref: KEGG:R01978
xref: MetaCyc:HYDROXYMETHYLGLUTARYL-COA-SYNTHASE-RXN
xref: RHEA:10191
is_a: GO:0046912 ! transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer

AmiGO

Last version checked
releases/2017-02-26.

23:02:2017 10:01.

slaulederkind
Last updated
1.1.2366

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