CHICK:HMCS1

Species (Taxon ID)	Gallus gallus (Chicken). (9031)
Gene Name(s)	HMGCS1 (synonyms: HMGCS)
Protein Name(s)	Hydroxymethylglutaryl-CoA synthase, cytoplasmic HMG-CoA synthase 3-hydroxy-3-methylglutaryl coenzyme A synthase
External Links
UniProt	P23228
EMBL	M60657
PIR	S13887
RefSeq	NP_990742.1
UniGene	Gga.4388
ProteinModelPortal	P23228
SMR	P23228
STRING	9031.ENSGALP00000038170
PaxDb	P23228
PRIDE	P23228
GeneID	396379
KEGG	gga:396379
CTD	3157
eggNOG	COG3425
HOGENOM	HOG000012351
HOVERGEN	HBG051912
InParanoid	P23228
KO	K01641
PhylomeDB	P23228
BRENDA	2.3.3.10
SABIO-RK	P23228
UniPathway	UPA00058
NextBio	20816421
PRO	PR:P23228
Proteomes	UP000000539
GO	GO:0005737 GO:0004421 GO:0006695 GO:0008299
Gene3D	3.40.47.10
InterPro	IPR000590 IPR013746 IPR013528 IPR010122 IPR016039
Pfam	PF08540 PF01154
SUPFAM	SSF53901
TIGRFAMs	TIGR01833
PROSITE	PS01226

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
involved_in	GO:0010142	farnesyl diphosphate biosynthetic process, mevalonate pathway		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN002457876 PomBase:SPAC4F8.14c	P		Seeded From UniProt	complete
involved_in	GO:0006084	acetyl-CoA metabolic process		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN002457876 PomBase:SPAC4F8.14c	P		Seeded From UniProt	complete
part_of	GO:0005829	cytosol		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000222445 RGD:70970	C		Seeded From UniProt	complete
enables	GO:0004421	hydroxymethylglutaryl-CoA synthase activity		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:101939 PANTHER:PTN002457876 PomBase:SPAC4F8.14c RGD:2804 RGD:70970 SGD:S000004595 TAIR:locus:2137015	F		Seeded From UniProt	complete
enables	GO:0003824	catalytic activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR016039	F		Seeded From UniProt	complete
enables	GO:0004421	hydroxymethylglutaryl-CoA synthase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000590 InterPro:IPR010122 InterPro:IPR013528 InterPro:IPR013746	F		Seeded From UniProt	complete
involved_in	GO:0008299	isoprenoid biosynthetic process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000590 InterPro:IPR010122 InterPro:IPR013528 InterPro:IPR013746	P		Seeded From UniProt	complete
enables	GO:0004421	hydroxymethylglutaryl-CoA synthase activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:2.3.3.10	F		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0963 UniProtKB-SubCell:SL-0086	C		Seeded From UniProt	complete
involved_in	GO:0006694	steroid biosynthetic process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0752	P		Seeded From UniProt	complete
involved_in	GO:0006629	lipid metabolic process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0443	P		Seeded From UniProt	complete
enables	GO:0016740	transferase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0808	F		Seeded From UniProt	complete
involved_in	GO:0016126	sterol biosynthetic process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0756	P		Seeded From UniProt	complete
involved_in	GO:0008202	steroid metabolic process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0753	P		Seeded From UniProt	complete
involved_in	GO:0008203	cholesterol metabolic process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0153	P		Seeded From UniProt	complete
involved_in	GO:0006695	cholesterol biosynthetic process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0152	P		Seeded From UniProt	complete
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References

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