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Category:GO:0000347 ! THO complex

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DAG for GO:0000347id: GO:0000347

name: THO complex
namespace: cellular_component
def: "The THO complex is a nuclear complex that is required for transcription elongation through genes containing tandemly repeated DNA sequences. The THO complex is also part of the TREX (TRanscription EXport) complex that is involved in coupling transcription to export of mRNAs to the cytoplasm. In S. cerevisiae, it is composed of four subunits: Hpr1p, Tho2p, Thp1p, and Mft1p, while the human complex is composed of 7 subunits." [GOC:krc, PMID:11060033, PMID:11979277, PMID:16983072]
subset: goslim_pir
is_a: GO:0032991 ! protein-containing complex
relationship: part_of: GO:0005634 ! nucleus

AmiGO <GOterm>GO:0000347</GOterm>
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Pages in category "GO:0000347 ! THO complex"

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