CHICK:WNT2B

Species (Taxon ID)	Gallus gallus (Chicken). (9031)
Gene Name(s)	WNT2B
Protein Name(s)	Protein Wnt-2b
External Links
UniProt	Q98SN7
EMBL	AF346628 AF182403
RefSeq	NP_989667.1
UniGene	Gga.50310
IntAct	Q98SN7
STRING	9031.ENSGALP00000039420
PaxDb	Q98SN7
PRIDE	Q98SN7
GeneID	374243
KEGG	gga:374243
CTD	7482
eggNOG	NOG284879
HOGENOM	HOG000039529
HOVERGEN	HBG001595
InParanoid	Q98SN7
KO	K00182
PhylomeDB	Q98SN7
NextBio	20813739
PRO	PR:Q98SN7
Proteomes	UP000000539
GO	GO:0005578 GO:0005109 GO:0060219 GO:0060070 GO:0008283 GO:0061303 GO:0060900 GO:0035115 GO:0061072 GO:0002088 GO:0002011 GO:0045686 GO:0045665 GO:0003407 GO:0030182 GO:0045743 GO:0060828 GO:0010842 GO:0016055
InterPro	IPR005817 IPR009140 IPR018161
PANTHER	PTHR12027
Pfam	PF00110
PRINTS	PR01842 PR01349
SMART	SM00097
PROSITE	PS00246

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
enables	GO:0005109	frizzled binding	PMID:12490564^[1]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:Q13467	F		Seeded From UniProt	complete
enables	GO:0005109	frizzled binding	PMID:12490564^[1]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:Q61088	F		Seeded From UniProt	complete
involved_in	GO:0060900	embryonic camera-type eye formation	PMID:12921742^[2]	ECO:0000270	expression pattern evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0060828	regulation of canonical Wnt signaling pathway	PMID:11290326^[3]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0060219	camera-type eye photoreceptor cell differentiation	PMID:16854977^[4]	ECO:0000270	expression pattern evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0060070	canonical Wnt signaling pathway	PMID:16854977^[4]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0060070	canonical Wnt signaling pathway	PMID:12490564^[1]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway	PMID:11290326^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0045686	negative regulation of glial cell differentiation	PMID:15901663^[5]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0045665	negative regulation of neuron differentiation	PMID:12490564^[1]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0045665	negative regulation of neuron differentiation	PMID:12921742^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0045665	negative regulation of neuron differentiation	PMID:15901663^[5]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0035115	embryonic forelimb morphogenesis	PMID:11290326^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0030182	neuron differentiation	PMID:16854977^[4]	ECO:0000270	expression pattern evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0016055	Wnt signaling pathway	PMID:12921742^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0010842	retina layer formation	PMID:12921742^[2]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0008283	cell population proliferation	PMID:15901663^[5]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0008283	cell population proliferation	PMID:12490564^[1]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0008283	cell population proliferation	PMID:10398532^[6]	ECO:0000270	expression pattern evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0002011	morphogenesis of an epithelial sheet	PMID:12921742^[2]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0061303	cornea development in camera-type eye	PMID:16258938^[7]	ECO:0000270	expression pattern evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0061072	iris morphogenesis	PMID:16258938^[7]	ECO:0000270	expression pattern evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0002088	lens development in camera-type eye	PMID:16258938^[7]	ECO:0000270	expression pattern evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0090270	regulation of fibroblast growth factor production	PMID:11290326^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	has_input:(UniProtKB:O42486) has_input:(UniProtKB:F1NHT7) occurs_in:(UBERON:0003372)	Seeded From UniProt	complete
enables	GO:0005109	frizzled binding	PMID:12490564^[1]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:Q61088	F		Seeded From UniProt	complete
enables	GO:0005109	frizzled binding	PMID:12490564^[1]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:Q13467	F		Seeded From UniProt	complete
involved_in	GO:0045165	cell fate commitment	PMID:21873635^[8]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:98957 PANTHER:PTN000246517 UniProtKB:P49339 ZFIN:ZDB-GENE-980526-332	P		Seeded From UniProt	complete
involved_in	GO:0030182	neuron differentiation	PMID:21873635^[8]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000246517 RGD:69250 UniProtKB:P56706 UniProtKB:Q98SN7	P		Seeded From UniProt	complete
involved_in	GO:0016055	Wnt signaling pathway	PMID:21873635^[8]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0010194 MGI:MGI:108061 MGI:MGI:1197020 MGI:MGI:98953 MGI:MGI:98954 MGI:MGI:98956 MGI:MGI:98958 MGI:MGI:98960 MGI:MGI:98961 MGI:MGI:98962 PANTHER:PTN000246517 UniProtKB:P41221 UniProtKB:Q98SN7 WB:WBGene00000858 WB:WBGene00003029 ZFIN:ZDB-GENE-980526-332	P		Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	PMID:21873635^[8]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0004009 MGI:MGI:98956 MGI:MGI:98957 PANTHER:PTN000246517 RGD:1311441 RGD:69250 UniProtKB:P41221 UniProtKB:P56704 UniProtKB:P56705 UniProtKB:Q2LMP1 UniProtKB:Q9UBV4 UniProtKB:Q9YGX6	C		Seeded From UniProt	complete
enables	GO:0005109	frizzled binding	PMID:21873635^[8]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0004009 FB:FBgn0004360 FB:FBgn0010453 FB:FBgn0038134 MGI:MGI:98956 MGI:MGI:98957 MGI:MGI:98958 MGI:MGI:98961 MGI:MGI:98962 PANTHER:PTN000246517 RGD:69079 UniProtKB:P09544 UniProtKB:P41221 UniProtKB:P56703 UniProtKB:Q98SN7	F		Seeded From UniProt	complete
enables	GO:0005102	signaling receptor binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR005817 InterPro:IPR009140	F		Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR005817 InterPro:IPR009140	C		Seeded From UniProt	complete
involved_in	GO:0007275	multicellular organism development	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR005817 InterPro:IPR009140	P		Seeded From UniProt	complete
involved_in	GO:0016055	Wnt signaling pathway	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR005817 InterPro:IPR009140	P		Seeded From UniProt	complete
involved_in	GO:0003407	neural retina development	PMID:15901663^[5]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0090271	positive regulation of fibroblast growth factor production	PMID:16575901^[9]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0060173	limb development	PMID:16575901^[9]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0964 UniProtKB-SubCell:SL-0243	C		Seeded From UniProt	complete
involved_in	GO:0007275	multicellular organism development	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0217	P		Seeded From UniProt	complete
involved_in	GO:0016055	Wnt signaling pathway	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0879	P		Seeded From UniProt	complete
edit table

Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 ^1.6 Kubo, F et al. (2003) Wnt2b controls retinal cell differentiation at the ciliary marginal zone. Development 130 587-98 PubMed GONUTS page
↑ ^2.0 ^2.1 ^2.2 ^2.3 ^2.4 Nakagawa, S et al. (2003) Identification of the laminar-inducing factor: Wnt-signal from the anterior rim induces correct laminar formation of the neural retina in vitro. Dev. Biol. 260 414-25 PubMed GONUTS page
↑ ^3.0 ^3.1 ^3.2 ^3.3 Kawakami, Y et al. (2001) WNT signals control FGF-dependent limb initiation and AER induction in the chick embryo. Cell 104 891-900 PubMed GONUTS page
↑ ^4.0 ^4.1 ^4.2 Cho, SH & Cepko, CL (2006) Wnt2b/beta-catenin-mediated canonical Wnt signaling determines the peripheral fates of the chick eye. Development 133 3167-77 PubMed GONUTS page
↑ ^5.0 ^5.1 ^5.2 ^5.3 Kubo, F et al. (2005) Wnt2b inhibits differentiation of retinal progenitor cells in the absence of Notch activity by downregulating the expression of proneural genes. Development 132 2759-70 PubMed GONUTS page
↑ Jasoni, C et al. (1999) Analysis of chicken Wnt-13 expression demonstrates coincidence with cell division in the developing eye and is consistent with a role in induction. Dev. Dyn. 215 215-24 PubMed GONUTS page
↑ ^7.0 ^7.1 ^7.2 Fokina, VM & Frolova, EI (2006) Expression patterns of Wnt genes during development of an anterior part of the chicken eye. Dev. Dyn. 235 496-505 PubMed GONUTS page
↑ ^8.0 ^8.1 ^8.2 ^8.3 ^8.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
↑ ^9.0 ^9.1 Dong, YF et al. (2006) Wnt induction of chondrocyte hypertrophy through the Runx2 transcription factor. J. Cell. Physiol. 208 77-86 PubMed GONUTS page

[PMID:12490564-1] 1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 ^1.6 Kubo, F et al. (2003) Wnt2b controls retinal cell differentiation at the ciliary marginal zone. Development 130 587-98 PubMed GONUTS page

[PMID:12921742-2] 2.0 ^2.1 ^2.2 ^2.3 ^2.4 Nakagawa, S et al. (2003) Identification of the laminar-inducing factor: Wnt-signal from the anterior rim induces correct laminar formation of the neural retina in vitro. Dev. Biol. 260 414-25 PubMed GONUTS page

[PMID:11290326-3] 3.0 ^3.1 ^3.2 ^3.3 Kawakami, Y et al. (2001) WNT signals control FGF-dependent limb initiation and AER induction in the chick embryo. Cell 104 891-900 PubMed GONUTS page

[PMID:16854977-4] 4.0 ^4.1 ^4.2 Cho, SH & Cepko, CL (2006) Wnt2b/beta-catenin-mediated canonical Wnt signaling determines the peripheral fates of the chick eye. Development 133 3167-77 PubMed GONUTS page

[PMID:15901663-5] 5.0 ^5.1 ^5.2 ^5.3 Kubo, F et al. (2005) Wnt2b inhibits differentiation of retinal progenitor cells in the absence of Notch activity by downregulating the expression of proneural genes. Development 132 2759-70 PubMed GONUTS page

[PMID:10398532-6] Jasoni, C et al. (1999) Analysis of chicken Wnt-13 expression demonstrates coincidence with cell division in the developing eye and is consistent with a role in induction. Dev. Dyn. 215 215-24 PubMed GONUTS page

[PMID:16258938-7] 7.0 ^7.1 ^7.2 Fokina, VM & Frolova, EI (2006) Expression patterns of Wnt genes during development of an anterior part of the chicken eye. Dev. Dyn. 235 496-505 PubMed GONUTS page

[PMID:21873635-8] 8.0 ^8.1 ^8.2 ^8.3 ^8.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:16575901-9] 9.0 ^9.1 Dong, YF et al. (2006) Wnt induction of chondrocyte hypertrophy through the Runx2 transcription factor. J. Cell. Physiol. 208 77-86 PubMed GONUTS page

[1]

[2]

[3]

[4]

[5]

[6]

[7]

[8]

[9]

CHICK:WNT2B

Contents

Annotations

Notes

References

a

c

d

e

f

g

i

l

m

n

p

r

s

t

v

w

Navigation menu

Personal tools

Namespaces

Variants

Views

More

Search

Navigation

Cacao

Links

Tools