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CHICK:VDR

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) VDR (synonyms: NR1I1)
Protein Name(s) Vitamin D3 receptor

VDR 1,25-dihydroxyvitamin D3 receptor Nuclear receptor subfamily 1 group I member 1

External Links
UniProt O42392
EMBL AF011356
PIR A60912
RefSeq NP_990429.1
UniGene Gga.584
ProteinModelPortal O42392
SMR O42392
BioGrid 676260
BindingDB O42392
ChEMBL CHEMBL2353
GeneID 395988
KEGG gga:395988
CTD 7421
HOVERGEN HBG108655
InParanoid O42392
KO K08539
PhylomeDB O42392
NextBio 20816052
PRO PR:O42392
Proteomes UP000000539
GO GO:0005634
GO:0008434
GO:0043565
GO:0003707
GO:0008270
Gene3D 1.10.565.10
3.30.50.10
InterPro IPR008946
IPR000536
IPR001723
IPR000324
IPR001628
IPR013088
Pfam PF00104
PF00105
PRINTS PR00398
PR00047
PR00350
SMART SM00430
SM00399
SUPFAM SSF48508
PROSITE PS00031
PS51030

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

part_of

GO:0005901

caveola

PMID:15272054[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0005499

vitamin D binding

PMID:15272054[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0004879

nuclear receptor activity

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P11473

F

Seeded From UniProt

complete

involved_in

GO:0070561

vitamin D receptor signaling pathway

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P11473

P

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:17156784[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0043401

steroid hormone mediated signaling pathway

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0003707

P

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000324
InterPro:IPR001723

F

Seeded From UniProt

complete

enables

GO:0003700

DNA-binding transcription factor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001628

F

Seeded From UniProt

complete

enables

GO:0003707

steroid hormone receptor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001723

F

Seeded From UniProt

complete

enables

GO:0004879

nuclear receptor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000324

F

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000324
InterPro:IPR001628
InterPro:IPR001723

C

Seeded From UniProt

complete

involved_in

GO:0006355

regulation of transcription, DNA-templated

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000324
InterPro:IPR001628
InterPro:IPR001723
InterPro:IPR013088

P

Seeded From UniProt

complete

enables

GO:0008270

zinc ion binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001628
InterPro:IPR013088

F

Seeded From UniProt

complete

enables

GO:0043565

sequence-specific DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001628

F

Seeded From UniProt

complete

involved_in

GO:0033280

response to vitamin D

PMID:15272054[1]

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

PMID:15272054[1]

ECO:0000304

author statement supported by traceable reference used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:15272054[1]

ECO:0000304

author statement supported by traceable reference used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0006816

calcium ion transport

PMID:17156784[2]

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0238

F

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 Huhtakangas, JA et al. (2004) The vitamin D receptor is present in caveolae-enriched plasma membranes and binds 1 alpha,25(OH)2-vitamin D3 in vivo and in vitro. Mol. Endocrinol. 18 2660-71 PubMed GONUTS page
  2. 2.0 2.1 Dornas, RA et al. (2007) Distribution of vitamin D3 receptor in the epididymal region of roosters (Gallus domesticus) is cell and segment specific. Gen. Comp. Endocrinol. 150 414-8 PubMed GONUTS page