CHICK:TNR16

Species (Taxon ID)	Gallus gallus (Chicken). (9031)
Gene Name(s)	NGFR (synonyms: TNFRSF16)
Protein Name(s)	Tumor necrosis factor receptor superfamily member 16 Gp80-LNGFR Low affinity neurotrophin receptor p75NTR Low-affinity nerve growth factor receptor NGF receptor p75 ICD
External Links
UniProt	P18519
PIR	JN0006
UniGene	Gga.39799
ProteinModelPortal	P18519
SMR	P18519
PaxDb	P18519
eggNOG	NOG39106
HOGENOM	HOG000059587
HOVERGEN	HBG060431
InParanoid	P18519
PhylomeDB	P18519
Proteomes	UP000000539
GO	GO:0016021 GO:0006915 GO:0030154 GO:0032922 GO:0007399 GO:0007165
Gene3D	1.10.533.10
InterPro	IPR011029 IPR000488 IPR001368 IPR022325
Pfam	PF00531 PF00020
PRINTS	PR01966
SMART	SM00005 SM00208
SUPFAM	SSF47986
PROSITE	PS50017 PS00652 PS50050

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
enables	GO:0048406	nerve growth factor binding	PMID:11559852^[1]	ECO:0000314	direct assay evidence used in manual assertion		F	Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	PMID:11559852^[1]	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
enables	GO:0043121	neurotrophin binding	PMID:11559852^[1]	ECO:0000314	direct assay evidence used in manual assertion		F	Seeded From UniProt	complete
involved_in	GO:0032922	circadian regulation of gene expression	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q9Z0W1	P	Seeded From UniProt	complete
enables	GO:0048406	nerve growth factor binding	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:97323 PANTHER:PTN001133900 RGD:3177 UniProtKB:P18519	F	Seeded From UniProt	complete
enables	GO:0015026	coreceptor activity	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN001133900 UniProtKB:P08138	F	Seeded From UniProt	complete
part_of	GO:0009986	cell surface	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:97323 PANTHER:PTN001133900 RGD:3177	C	Seeded From UniProt	complete
involved_in	GO:0007266	Rho protein signal transduction	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN001133900 UniProtKB:P08138	P	Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:97323 PANTHER:PTN001133900 RGD:3177 UniProtKB:P08138 UniProtKB:P18519	C	Seeded From UniProt	complete
enables	GO:0005035	death receptor activity	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:97323 PANTHER:PTN001133900 UniProtKB:P08138	F	Seeded From UniProt	complete
involved_in	GO:1904646	cellular response to amyloid-beta	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P08138 ensembl:ENSP00000172229	P	Seeded From UniProt	complete
involved_in	GO:1903588	negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P08138 ensembl:ENSP00000172229	P	Seeded From UniProt	complete
involved_in	GO:1902895	positive regulation of pri-miRNA transcription by RNA polymerase II	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P08138 ensembl:ENSP00000172229	P	Seeded From UniProt	complete
involved_in	GO:1900182	positive regulation of protein localization to nucleus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P08138 ensembl:ENSP00000172229	P	Seeded From UniProt	complete
involved_in	GO:0051402	neuron apoptotic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P08138 ensembl:ENSP00000172229	P	Seeded From UniProt	complete
enables	GO:0031625	ubiquitin protein ligase binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P08138 ensembl:ENSP00000172229	F	Seeded From UniProt	complete
enables	GO:0015026	coreceptor activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P08138 ensembl:ENSP00000172229	F	Seeded From UniProt	complete
involved_in	GO:0007266	Rho protein signal transduction	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P08138 ensembl:ENSP00000172229	P	Seeded From UniProt	complete
involved_in	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P08138 ensembl:ENSP00000172229	P	Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P08138 ensembl:ENSP00000172229	C	Seeded From UniProt	complete
enables	GO:0005516	calmodulin binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P08138 ensembl:ENSP00000172229	F	Seeded From UniProt	complete
enables	GO:0005035	death receptor activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P08138 ensembl:ENSP00000172229	F	Seeded From UniProt	complete
involved_in	GO:0007165	signal transduction	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000488	P	Seeded From UniProt	complete
involved_in	GO:0006915	apoptotic process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0053	P	Seeded From UniProt	complete
involved_in	GO:0048511	rhythmic process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0090	P	Seeded From UniProt	complete
involved_in	GO:0007275	multicellular organism development	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0217	P	Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0812	C	Seeded From UniProt	complete
involved_in	GO:0030154	cell differentiation	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0221	P	Seeded From UniProt	complete
involved_in	GO:0007399	nervous system development	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0524	P	Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472 UniProtKB-SubCell:SL-0162	C	Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 von Schack, D et al. (2001) Complete ablation of the neurotrophin receptor p75NTR causes defects both in the nervous and the vascular system. Nat. Neurosci. 4 977-8 PubMed GONUTS page
↑ ^2.0 ^2.1 ^2.2 ^2.3 ^2.4 ^2.5 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:11559852-1] 1.0 ^1.1 ^1.2 von Schack, D et al. (2001) Complete ablation of the neurotrophin receptor p75NTR causes defects both in the nervous and the vascular system. Nat. Neurosci. 4 977-8 PubMed GONUTS page

[PMID:21873635-2] 2.0 ^2.1 ^2.2 ^2.3 ^2.4 ^2.5 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

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CHICK:TNR16

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