GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.

Have any questions? Please email us at ecoliwiki@gmail.com

CHICK:TGFB1

From GONUTS
Jump to: navigation, search
Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) TGFB1
Protein Name(s) Transforming growth factor beta-1

TGF-beta-1 Latency-associated peptide LAP

External Links
UniProt P09531
EMBL M31160
PIR A41918
UniGene Gga.929
ProteinModelPortal P09531
SMR P09531
HOVERGEN HBG074115
InParanoid P09531
PhylomeDB P09531
Proteomes UP000000539
GO GO:0005615
GO:0016049
GO:0051781
GO:0046881
GO:0033686
GO:0042327
GO:0042701
GO:0050708
Gene3D 2.10.90.10
InterPro IPR029034
IPR001839
IPR001111
IPR016319
IPR015615
IPR003939
IPR017948
PANTHER PTHR11848
Pfam PF00019
PF00688
PIRSF PIRSF001787
PRINTS PR01423
PR01424
SMART SM00204
SUPFAM SSF57501
PROSITE PS00250
PS51362

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0014008

positive regulation of microglia differentiation

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P04202

P

Seeded From UniProt

complete

involved_in

GO:0050708

regulation of protein secretion

PMID:15269104[1]

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0046881

positive regulation of follicle-stimulating hormone secretion

PMID:15269104[1]

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0042701

progesterone secretion

PMID:15269104[1]

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0042327

positive regulation of phosphorylation

PMID:15269104[1]

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0033686

positive regulation of luteinizing hormone secretion

PMID:15269104[1]

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0060395

SMAD protein signal transduction

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1338027
MGI:MGI:88180
MGI:MGI:88182
MGI:MGI:95689
MGI:MGI:97359
PANTHER:PTN000218063
UniProtKB:O95390
UniProtKB:P12643
UniProtKB:P12644
UniProtKB:P18075
UniProtKB:P22004
UniProtKB:P43026
UniProtKB:P61812
UniProtKB:Q6KF10
UniProtKB:Q99988

P

Seeded From UniProt

complete

involved_in

GO:0048468

cell development

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:103302
PANTHER:PTN000218063

P

Seeded From UniProt

complete

involved_in

GO:0043408

regulation of MAPK cascade

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:107335
PANTHER:PTN000218063

P

Seeded From UniProt

complete

involved_in

GO:0042981

regulation of apoptotic process

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:98726
PANTHER:PTN000218063

P

Seeded From UniProt

complete

involved_in

GO:0042127

regulation of cell population proliferation

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:98725
PANTHER:PTN000218722

P

Seeded From UniProt

complete

involved_in

GO:0010862

positive regulation of pathway-restricted SMAD protein phosphorylation

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:107335
MGI:MGI:1338820
MGI:MGI:88182
MGI:MGI:95684
MGI:MGI:98727
PANTHER:PTN000218063
UniProtKB:O95393
UniProtKB:P01137
UniProtKB:P08476
UniProtKB:P12643
UniProtKB:P12644
UniProtKB:P18075
UniProtKB:P22003
UniProtKB:P22004
UniProtKB:Q6KF10
UniProtKB:Q7Z4P5
UniProtKB:Q96S42
UniProtKB:Q9UK05

P

Seeded From UniProt

complete

involved_in

GO:0007179

transforming growth factor beta receptor signaling pathway

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:98725
PANTHER:PTN000218722
UniProtKB:P01137
UniProtKB:P10600
UniProtKB:P61812

P

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0000490
MGI:MGI:103302
MGI:MGI:1338027
MGI:MGI:88177
MGI:MGI:88180
MGI:MGI:95691
MGI:MGI:98725
MGI:MGI:98726
PANTHER:PTN000218063
RGD:1305979
RGD:2211
RGD:2212
RGD:2213
RGD:2214
RGD:2912
RGD:2913
RGD:3115
RGD:3851
RGD:62074
RGD:620743
RGD:621512
RGD:69051
RGD:70491
UniProtKB:O14793
UniProtKB:O42220
UniProtKB:O95393
UniProtKB:P01137
UniProtKB:P12643
UniProtKB:P12644
UniProtKB:P18075
UniProtKB:P30371
UniProtKB:P61812
UniProtKB:Q96S42
UniProtKB:Q99988
WB:WBGene00000903

C

Seeded From UniProt

complete

enables

GO:0005160

transforming growth factor beta receptor binding

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:98725
PANTHER:PTN000218063
UniProtKB:P61812

F

Seeded From UniProt

complete

enables

GO:0005125

cytokine activity

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000218063
UniProtKB:P08476
UniProtKB:P12644

F

Seeded From UniProt

complete

enables

GO:0005114

type II transforming growth factor beta receptor binding

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000218722
UniProtKB:P01137
UniProtKB:P10600
UniProtKB:P61812

F

Seeded From UniProt

complete

involved_in

GO:0010469

regulation of signaling receptor activity

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0008083

P

Seeded From UniProt

complete

involved_in

GO:0010469

regulation of signaling receptor activity

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0005125

P

Seeded From UniProt

complete

involved_in

GO:0010469

regulation of signaling receptor activity

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0008083

P

Seeded From UniProt

complete

enables

GO:0005160

transforming growth factor beta receptor binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003939

F

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR016319

C

Seeded From UniProt

complete

enables

GO:0008083

growth factor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001839
InterPro:IPR017948

F

Seeded From UniProt

complete

enables

GO:0008083

growth factor activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0339

F

Seeded From UniProt

complete

involved_in

GO:0051781

positive regulation of cell division

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0497

P

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0964
UniProtKB-SubCell:SL-0243

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 Johnson, AL et al. (2004) Cellular mechanisms and modulation of activin A- and transforming growth factor beta-mediated differentiation in cultured hen granulosa cells. Biol. Reprod. 71 1844-51 PubMed GONUTS page
  2. 2.00 2.01 2.02 2.03 2.04 2.05 2.06 2.07 2.08 2.09 2.10 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page