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CHICK:TBX20

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) TBX20
Protein Name(s) T-box transcription factor TBX20

T-box protein 20 cTbx20

External Links
UniProt Q8UW76
EMBL AB070554
RefSeq NP_989475.1
UniGene Gga.4201
ProteinModelPortal Q8UW76
SMR Q8UW76
STRING 9031.ENSGALP00000019818
PaxDb Q8UW76
PRIDE Q8UW76
Ensembl ENSGALT00000019845
GeneID 373943
KEGG gga:373943
CTD 57057
eggNOG NOG272513
GeneTree ENSGT00760000118897
HOGENOM HOG000286000
HOVERGEN HBG067710
InParanoid Q8UW76
KO K10185
OMA TVMTPFV
OrthoDB EOG7GN2PM
PhylomeDB Q8UW76
TreeFam TF106341
NextBio 20813475
PRO PR:Q8UW76
Proteomes UP000000539
GO GO:0005737
GO:0005634
GO:0000977
GO:0001105
GO:0003700
GO:0003180
GO:0060413
GO:0008015
GO:0003207
GO:0055008
GO:0003215
GO:0008283
GO:0009953
GO:0036306
GO:0003272
GO:0035922
GO:0001947
GO:0006936
GO:0010991
GO:0000122
GO:0001764
GO:0003148
GO:0001569
GO:0003344
GO:0060045
GO:0003193
GO:0060577
GO:0003175
GO:0021524
Gene3D 2.60.40.820
InterPro IPR008967
IPR001699
IPR018186
PANTHER PTHR11267
Pfam PF00907
PRINTS PR00937
SMART SM00425
SUPFAM SSF49417
PROSITE PS01283
PS01264
PS50252

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0060973

cell migration involved in heart development

PMID:18353304[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

occurs_in:(UBERON:0002062)

Seeded From UniProt

complete

involved_in

GO:0030335

positive regulation of cell migration

PMID:18353304[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

occurs_in:(UBERON:0002062)

Seeded From UniProt

complete

involved_in

GO:0010628

positive regulation of gene expression

PMID:17064679[2]

ECO:0000314

direct assay evidence used in manual assertion

P

occurs_in:(UBERON:0002062)

Seeded From UniProt

complete

involved_in

GO:0010629

negative regulation of gene expression

PMID:17064679[2]

ECO:0000314

direct assay evidence used in manual assertion

P

occurs_in:(UBERON:0002062)

Seeded From UniProt

complete

involved_in

GO:2000793

cell proliferation involved in heart valve development

PMID:17064679[2]

ECO:0000314

direct assay evidence used in manual assertion

P

occurs_in:(UBERON:0002062)

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:17064679[2]

ECO:0000314

direct assay evidence used in manual assertion

C

part_of:(UBERON:0002062)

Seeded From UniProt

complete

involved_in

GO:0060045

positive regulation of cardiac muscle cell proliferation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9ES03
ensembl:ENSMUSP00000052591

P

Seeded From UniProt

complete

involved_in

GO:0055008

cardiac muscle tissue morphogenesis

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9ES03
ensembl:ENSMUSP00000052591

P

Seeded From UniProt

complete

involved_in

GO:0045944

positive regulation of transcription by RNA polymerase II

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9ES03
ensembl:ENSMUSP00000052591

P

Seeded From UniProt

complete

involved_in

GO:0045893

positive regulation of transcription, DNA-templated

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9ES03
ensembl:ENSMUSP00000052591

P

Seeded From UniProt

complete

involved_in

GO:0045892

negative regulation of transcription, DNA-templated

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9ES03
ensembl:ENSMUSP00000052591

P

Seeded From UniProt

complete

involved_in

GO:0036306

embryonic heart tube elongation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9ES03
ensembl:ENSMUSP00000052591

P

Seeded From UniProt

complete

involved_in

GO:0035050

embryonic heart tube development

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9ES03
ensembl:ENSMUSP00000052591

P

Seeded From UniProt

complete

involved_in

GO:0021524

visceral motor neuron differentiation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9ES03
ensembl:ENSMUSP00000052591

P

Seeded From UniProt

complete

involved_in

GO:0010991

negative regulation of SMAD protein complex assembly

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9ES03
ensembl:ENSMUSP00000052591

P

Seeded From UniProt

complete

involved_in

GO:0009953

dorsal/ventral pattern formation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9ES03
ensembl:ENSMUSP00000052591

P

Seeded From UniProt

complete

involved_in

GO:0008283

cell population proliferation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9ES03
ensembl:ENSMUSP00000052591

P

Seeded From UniProt

complete

involved_in

GO:0008015

blood circulation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9ES03
ensembl:ENSMUSP00000052591

P

Seeded From UniProt

complete

involved_in

GO:0006936

muscle contraction

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9ES03
ensembl:ENSMUSP00000052591

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9ES03
ensembl:ENSMUSP00000052591

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9ES03
ensembl:ENSMUSP00000052591

C

Seeded From UniProt

complete

enables

GO:0003700

DNA-binding transcription factor activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9ES03
ensembl:ENSMUSP00000052591

F

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9ES03
ensembl:ENSMUSP00000052591

F

Seeded From UniProt

complete

involved_in

GO:0003344

pericardium morphogenesis

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9ES03
ensembl:ENSMUSP00000052591

P

Seeded From UniProt

complete

involved_in

GO:0003279

cardiac septum development

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9ES03
ensembl:ENSMUSP00000052591

P

Seeded From UniProt

complete

involved_in

GO:0003272

endocardial cushion formation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9ES03
ensembl:ENSMUSP00000052591

P

Seeded From UniProt

complete

involved_in

GO:0003215

cardiac right ventricle morphogenesis

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9ES03
ensembl:ENSMUSP00000052591

P

Seeded From UniProt

complete

involved_in

GO:0003207

cardiac chamber formation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9ES03
ensembl:ENSMUSP00000052591

P

Seeded From UniProt

complete

involved_in

GO:0003203

endocardial cushion morphogenesis

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9ES03
ensembl:ENSMUSP00000052591

P

Seeded From UniProt

complete

involved_in

GO:0003193

pulmonary valve formation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9ES03
ensembl:ENSMUSP00000052591

P

Seeded From UniProt

complete

involved_in

GO:0003176

aortic valve development

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9ES03
ensembl:ENSMUSP00000052591

P

Seeded From UniProt

complete

involved_in

GO:0003175

tricuspid valve development

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9ES03
ensembl:ENSMUSP00000052591

P

Seeded From UniProt

complete

involved_in

GO:0003151

outflow tract morphogenesis

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9ES03
ensembl:ENSMUSP00000052591

P

Seeded From UniProt

complete

involved_in

GO:0003148

outflow tract septum morphogenesis

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9ES03
ensembl:ENSMUSP00000052591

P

Seeded From UniProt

complete

involved_in

GO:0003143

embryonic heart tube morphogenesis

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9ES03
ensembl:ENSMUSP00000052591

P

Seeded From UniProt

complete

involved_in

GO:0001947

heart looping

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9ES03
ensembl:ENSMUSP00000052591

P

Seeded From UniProt

complete

involved_in

GO:0001764

neuron migration

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9ES03
ensembl:ENSMUSP00000052591

P

Seeded From UniProt

complete

involved_in

GO:0001569

branching involved in blood vessel morphogenesis

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9ES03
ensembl:ENSMUSP00000052591

P

Seeded From UniProt

complete

enables

GO:0001228

DNA-binding transcription activator activity, RNA polymerase II-specific

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9ES03
ensembl:ENSMUSP00000052591

F

Seeded From UniProt

complete

enables

GO:0001102

RNA polymerase II activating transcription factor binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9ES03
ensembl:ENSMUSP00000052591

F

Seeded From UniProt

complete

enables

GO:0001085

RNA polymerase II transcription factor binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9ES03
ensembl:ENSMUSP00000052591

F

Seeded From UniProt

complete

enables

GO:0000981

DNA-binding transcription factor activity, RNA polymerase II-specific

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9ES03
ensembl:ENSMUSP00000052591

F

Seeded From UniProt

complete

enables

GO:0000978

RNA polymerase II proximal promoter sequence-specific DNA binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9ES03
ensembl:ENSMUSP00000052591

F

Seeded From UniProt

complete

enables

GO:0000977

RNA polymerase II regulatory region sequence-specific DNA binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9ES03
ensembl:ENSMUSP00000052591

F

Seeded From UniProt

complete

involved_in

GO:0000122

negative regulation of transcription by RNA polymerase II

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9ES03
ensembl:ENSMUSP00000052591

P

Seeded From UniProt

complete

involved_in

GO:0060577

pulmonary vein morphogenesis

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9UMR3
ensembl:ENSP00000386170

P

Seeded From UniProt

complete

involved_in

GO:0060413

atrial septum morphogenesis

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9UMR3
ensembl:ENSP00000386170

P

Seeded From UniProt

complete

involved_in

GO:0035922

foramen ovale closure

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9UMR3
ensembl:ENSP00000386170

P

Seeded From UniProt

complete

involved_in

GO:0003180

aortic valve morphogenesis

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9UMR3
ensembl:ENSP00000386170

P

Seeded From UniProt

complete

involved_in

GO:0003148

outflow tract septum morphogenesis

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9UMR3
ensembl:ENSP00000386170

P

Seeded From UniProt

complete

enables

GO:0000981

DNA-binding transcription factor activity, RNA polymerase II-specific

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9UMR3
ensembl:ENSP00000386170

F

Seeded From UniProt

complete

enables

GO:0000977

RNA polymerase II regulatory region sequence-specific DNA binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9UMR3
ensembl:ENSP00000386170

F

Seeded From UniProt

complete

enables

GO:0003700

DNA-binding transcription factor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001699
InterPro:IPR008967
InterPro:IPR018186
InterPro:IPR036960

F

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001699
InterPro:IPR018186
InterPro:IPR036960

C

Seeded From UniProt

complete

involved_in

GO:0006355

regulation of transcription, DNA-templated

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001699
InterPro:IPR008967
InterPro:IPR018186
InterPro:IPR036960

P

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0238

F

Seeded From UniProt

complete

involved_in

GO:0007275

multicellular organism development

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0217

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Shelton, EL & Yutzey, KE (2008) Twist1 function in endocardial cushion cell proliferation, migration, and differentiation during heart valve development. Dev. Biol. 317 282-95 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Shelton, EL & Yutzey, KE (2007) Tbx20 regulation of endocardial cushion cell proliferation and extracellular matrix gene expression. Dev. Biol. 302 376-88 PubMed GONUTS page