CHICK:SOX10

Species (Taxon ID)	Gallus gallus (Chicken). (9031)
Gene Name(s)	SOX10
Protein Name(s)	Transcription factor SOX-10 cSOX10
External Links
UniProt	Q9W757
EMBL	AF152356 AJ245601
RefSeq	NP_990123.1
UniGene	Gga.4428
ProteinModelPortal	Q9W757
SMR	Q9W757
STRING	9031.ENSGALP00000020056
PaxDb	Q9W757
GeneID	395573
KEGG	gga:395573
CTD	6663
eggNOG	NOG295709
HOGENOM	HOG000108876
HOVERGEN	HBG002061
InParanoid	Q9W757
KO	K09270
OrthoDB	EOG7Q2N5K
PhylomeDB	Q9W757
NextBio	20815647
PRO	PR:Q9W757
Proteomes	UP000000539
ExpressionAtlas	Q9W757
GO	GO:0031315 GO:0005634 GO:0003682 GO:0000978 GO:0000980 GO:0003705 GO:0001190 GO:0060959 GO:0048469 GO:0048589 GO:0048546 GO:0048484 GO:0030318 GO:0043066 GO:0090090 GO:0001755 GO:0048709 GO:0007422 GO:0014015 GO:0002052
Gene3D	1.10.30.10
InterPro	IPR009071 IPR022151
Pfam	PF00505 PF12444
SMART	SM00398
SUPFAM	SSF47095
PROSITE	PS50118

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
enables	GO:0003700	DNA-binding transcription factor activity	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q04888	F		Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q04888	F		Seeded From UniProt	complete
involved_in	GO:0048709	oligodendrocyte differentiation	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q04888	P		Seeded From UniProt	complete
involved_in	GO:0045893	positive regulation of transcription, DNA-templated	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q04888	P		Seeded From UniProt	complete
involved_in	GO:0022010	central nervous system myelination	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q04888	P		Seeded From UniProt	complete
involved_in	GO:0014003	oligodendrocyte development	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q04888	P		Seeded From UniProt	complete
part_of	GO:0005623	cell	PMID:19464348^[1]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(CL:0000333)	Seeded From UniProt	complete
involved_in	GO:0060959	cardiac neuron development	PMID:12351187^[2]	ECO:0000270	expression pattern evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0048709	oligodendrocyte differentiation	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:98358 MGI:MGI:98370 MGI:MGI:98371 PANTHER:PTN001615967 UniProtKB:P57074	P		Seeded From UniProt	complete
involved_in	GO:0048484	enteric nervous system development	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:98358 PANTHER:PTN000030527	P		Seeded From UniProt	complete
involved_in	GO:0045944	positive regulation of transcription by RNA polymerase II	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:98358 MGI:MGI:98370 MGI:MGI:98371 PANTHER:PTN000741645 RGD:620474 UniProtKB:O18896 UniProtKB:P48436 UniProtKB:P57073	P		Seeded From UniProt	complete
involved_in	GO:0007422	peripheral nervous system development	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:98358 PANTHER:PTN000030527	P		Seeded From UniProt	complete
involved_in	GO:0007417	central nervous system development	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:98371 PANTHER:PTN001615967	P		Seeded From UniProt	complete
involved_in	GO:0002009	morphogenesis of an epithelium	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000741645 UniProtKB:P48434	P		Seeded From UniProt	complete
involved_in	GO:0001755	neural crest cell migration	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:98358 PANTHER:PTN000030527	P		Seeded From UniProt	complete
enables	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:98371 PANTHER:PTN000741645	F		Seeded From UniProt	complete
enables	GO:0042802	identical protein binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P56693 ensembl:ENSP00000380093	F		Seeded From UniProt	complete
part_of	GO:0005654	nucleoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P56693 ensembl:ENSP00000380093	C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P56693 ensembl:ENSP00000380093	C		Seeded From UniProt	complete
involved_in	GO:0090090	negative regulation of canonical Wnt signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q04888 ensembl:ENSMUSP00000155574	P		Seeded From UniProt	complete
involved_in	GO:0061138	morphogenesis of a branching epithelium	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q04888 ensembl:ENSMUSP00000155574	P		Seeded From UniProt	complete
involved_in	GO:0048709	oligodendrocyte differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q04888 ensembl:ENSMUSP00000155574	P		Seeded From UniProt	complete
involved_in	GO:0048589	developmental growth	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q04888 ensembl:ENSMUSP00000155574	P		Seeded From UniProt	complete
involved_in	GO:0048546	digestive tract morphogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q04888 ensembl:ENSMUSP00000155574	P		Seeded From UniProt	complete
involved_in	GO:0048484	enteric nervous system development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q04888 ensembl:ENSMUSP00000155574	P		Seeded From UniProt	complete
involved_in	GO:0048469	cell maturation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q04888 ensembl:ENSMUSP00000155574	P		Seeded From UniProt	complete
involved_in	GO:0045944	positive regulation of transcription by RNA polymerase II	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q04888 ensembl:ENSMUSP00000155574	P		Seeded From UniProt	complete
involved_in	GO:0045893	positive regulation of transcription, DNA-templated	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q04888 ensembl:ENSMUSP00000155574	P		Seeded From UniProt	complete
enables	GO:0044212	transcription regulatory region DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q04888 ensembl:ENSMUSP00000155574	F		Seeded From UniProt	complete
involved_in	GO:0043066	negative regulation of apoptotic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q04888 ensembl:ENSMUSP00000155574	P		Seeded From UniProt	complete
involved_in	GO:0032808	lacrimal gland development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q04888 ensembl:ENSMUSP00000155574	P		Seeded From UniProt	complete
part_of	GO:0031315	extrinsic component of mitochondrial outer membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q04888 ensembl:ENSMUSP00000155574	C		Seeded From UniProt	complete
involved_in	GO:0030318	melanocyte differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q04888 ensembl:ENSMUSP00000155574	P		Seeded From UniProt	complete
involved_in	GO:0030154	cell differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q04888 ensembl:ENSMUSP00000155574	P		Seeded From UniProt	complete
involved_in	GO:0022010	central nervous system myelination	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q04888 ensembl:ENSMUSP00000155574	P		Seeded From UniProt	complete
involved_in	GO:0014015	positive regulation of gliogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q04888 ensembl:ENSMUSP00000155574	P		Seeded From UniProt	complete
involved_in	GO:0014003	oligodendrocyte development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q04888 ensembl:ENSMUSP00000155574	P		Seeded From UniProt	complete
enables	GO:0008134	transcription factor binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q04888 ensembl:ENSMUSP00000155574	F		Seeded From UniProt	complete
involved_in	GO:0007422	peripheral nervous system development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q04888 ensembl:ENSMUSP00000155574	P		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q04888 ensembl:ENSMUSP00000155574	C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q04888 ensembl:ENSMUSP00000155574	C		Seeded From UniProt	complete
enables	GO:0003700	DNA-binding transcription factor activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q04888 ensembl:ENSMUSP00000155574	F		Seeded From UniProt	complete
enables	GO:0003682	chromatin binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q04888 ensembl:ENSMUSP00000155574	F		Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q04888 ensembl:ENSMUSP00000155574	F		Seeded From UniProt	complete
involved_in	GO:0002052	positive regulation of neuroblast proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q04888 ensembl:ENSMUSP00000155574	P		Seeded From UniProt	complete
involved_in	GO:0001755	neural crest cell migration	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q04888 ensembl:ENSMUSP00000155574	P		Seeded From UniProt	complete
enables	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q04888 ensembl:ENSMUSP00000155574	F		Seeded From UniProt	complete
enables	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q04888 ensembl:ENSMUSP00000155574	F		Seeded From UniProt	complete
enables	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q04888 ensembl:ENSMUSP00000155574	F		Seeded From UniProt	complete
part_of	GO:0005654	nucleoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:A0A024R1N6 ensembl:ENSP00000380093	C		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0963 UniProtKB-SubCell:SL-0086	C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0539 UniProtKB-SubCell:SL-0191	C		Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0238	F		Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ Aquino, JB et al. (2009) The retinoic acid inducible Cas-family signaling protein Nedd9 regulates neural crest cell migration by modulating adhesion and actin dynamics. Neuroscience 162 1106-19 PubMed GONUTS page
↑ Montero, JA et al. (2002) Expression of Sox8, Sox9 and Sox10 in the developing valves and autonomic nerves of the embryonic heart. Mech. Dev. 118 199-202 PubMed GONUTS page
↑ ^3.0 ^3.1 ^3.2 ^3.3 ^3.4 ^3.5 ^3.6 ^3.7 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:19464348-1] Aquino, JB et al. (2009) The retinoic acid inducible Cas-family signaling protein Nedd9 regulates neural crest cell migration by modulating adhesion and actin dynamics. Neuroscience 162 1106-19 PubMed GONUTS page

[PMID:12351187-2] Montero, JA et al. (2002) Expression of Sox8, Sox9 and Sox10 in the developing valves and autonomic nerves of the embryonic heart. Mech. Dev. 118 199-202 PubMed GONUTS page

[PMID:21873635-3] 3.0 ^3.1 ^3.2 ^3.3 ^3.4 ^3.5 ^3.6 ^3.7 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

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CHICK:SOX10

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Annotations

Notes

References

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