CHICK:RAD51

Species (Taxon ID)	Gallus gallus (Chicken). (9031)
Gene Name(s)	RAD51A (synonyms: RAD51)
Protein Name(s)	DNA repair protein RAD51 homolog 1
External Links
UniProt	P37383
EMBL	L09655 S59426
PIR	S35642
RefSeq	NP_990504.1
UniGene	Gga.2303
ProteinModelPortal	P37383
SMR	P37383
STRING	9031.ENSGALP00000032107
PaxDb	P37383
Ensembl	ENSGALT00000032744
GeneID	396086
KEGG	gga:396086
CTD	5888
eggNOG	COG0468
GeneTree	ENSGT00770000120539
HOGENOM	HOG000227426
HOVERGEN	HBG001504
InParanoid	P37383
KO	K04482
OMA	CQLPIDQ
OrthoDB	EOG715Q4H
PhylomeDB	P37383
TreeFam	TF101218
Reactome	REACT_115626 REACT_115715 REACT_197522 REACT_242347 REACT_247298
NextBio	20816144
PRO	PR:P37383
Proteomes	UP000000539
GO	GO:0000793 GO:0000794 GO:0000800 GO:0005739 GO:0000228 GO:0005730 GO:0005654 GO:0005634 GO:0048471 GO:0016605 GO:0005524 GO:0003684 GO:0003690 GO:0043142 GO:0072757 GO:0071479 GO:0006281 GO:0006268 GO:0006302 GO:0000724 GO:0007126 GO:0051106 GO:0051260 GO:0010569
Gene3D	3.40.50.300
InterPro	IPR003593 IPR011941 IPR013632 IPR016467 IPR010995 IPR003583 IPR027417 IPR020588 IPR020587
Pfam	PF08423
PIRSF	PIRSF005856
SMART	SM00382 SM00278
SUPFAM	SSF47794 SSF52540
TIGRFAMs	TIGR02239
PROSITE	PS50162 PS50163

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
part_of	GO:0005737	cytoplasm	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q06609	C	Seeded From UniProt	complete
enables	GO:0043142	single-stranded DNA-dependent ATPase activity	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q06609	F	Seeded From UniProt	complete
enables	GO:0003697	single-stranded DNA binding	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q06609	F	Seeded From UniProt	complete
enables	GO:0003690	double-stranded DNA binding	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q06609	F	Seeded From UniProt	complete
involved_in	GO:0006974	cellular response to DNA damage stimulus	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q06609	P	Seeded From UniProt	complete
involved_in	GO:0000730	DNA recombinase assembly	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q06609	P	Seeded From UniProt	complete
involved_in	GO:0000724	double-strand break repair via homologous recombination	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q06609	P	Seeded From UniProt	complete
involved_in	GO:0051321	meiotic cell cycle	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q08297	P	Seeded From UniProt	complete
involved_in	GO:0006268	DNA unwinding involved in DNA replication	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q06609	P	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q06609	C	Seeded From UniProt	complete
part_of	GO:0000794	condensed nuclear chromosome	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q08297	C	Seeded From UniProt	complete
part_of	GO:0000793	condensed chromosome	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q08297	C	Seeded From UniProt	complete
part_of	GO:0000228	nuclear chromosome	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q06609	C	Seeded From UniProt	complete
involved_in	GO:0070192	chromosome organization involved in meiotic cell cycle	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:97890 PANTHER:PTN000534635	P	Seeded From UniProt	complete
involved_in	GO:0042148	strand invasion	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN001415033 PomBase:SPAC644.14c PomBase:SPAC8E11.03c SGD:S000000897	P	Seeded From UniProt	complete
enables	GO:0008094	DNA-dependent ATPase activity	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN001415033 PomBase:SPAC8E11.03c SGD:S000000897 UniProtKB:Q8IIS8 WB:WBGene00004297	F	Seeded From UniProt	complete
involved_in	GO:0007131	reciprocal meiotic recombination	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000534635 SGD:S000000897	P	Seeded From UniProt	complete
involved_in	GO:0006312	mitotic recombination	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN001415033 PomBase:SPAC644.14c UniProtKB:C8VSQ3	P	Seeded From UniProt	complete
enables	GO:0003697	single-stranded DNA binding	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:97890 PANTHER:PTN001415033 PomBase:SPAC644.14c PomBase:SPAC8E11.03c SGD:S000000897 SGD:S000000981 UniProtKB:A0A1D8PFE4 UniProtKB:Q06609	F	Seeded From UniProt	complete
enables	GO:0003690	double-stranded DNA binding	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN001415033 PomBase:SPAC644.14c PomBase:SPAC8E11.03c SGD:S000000981 UniProtKB:A0A1D8PFE4 UniProtKB:Q06609 WB:WBGene00004297	F	Seeded From UniProt	complete
part_of	GO:0000794	condensed nuclear chromosome	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:97890 PANTHER:PTN000534635 SGD:S000000897 WB:WBGene00004297	C	Seeded From UniProt	complete
involved_in	GO:0000730	DNA recombinase assembly	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN001415033 PomBase:SPAC20H4.07 SGD:S000002411 UniProtKB:Q06609	P	Seeded From UniProt	complete
enables	GO:0000150	recombinase activity	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN001415033 PomBase:SPAC644.14c PomBase:SPAC8E11.03c SGD:S000000897 SGD:S000000981 UniProtKB:Q8IIS8 WB:WBGene00004297	F	Seeded From UniProt	complete
involved_in	GO:1990414	replication-born double-strand break repair via sister chromatid exchange	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q08297 ensembl:ENSMUSP00000028795	P	Seeded From UniProt	complete
involved_in	GO:0072711	cellular response to hydroxyurea	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q08297 ensembl:ENSMUSP00000028795	P	Seeded From UniProt	complete
involved_in	GO:0071312	cellular response to alkaloid	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q08297 ensembl:ENSMUSP00000028795	P	Seeded From UniProt	complete
involved_in	GO:0070192	chromosome organization involved in meiotic cell cycle	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q08297 ensembl:ENSMUSP00000028795	P	Seeded From UniProt	complete
involved_in	GO:0051321	meiotic cell cycle	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q08297 ensembl:ENSMUSP00000028795	P	Seeded From UniProt	complete
involved_in	GO:0032200	telomere organization	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q08297 ensembl:ENSMUSP00000028795	P	Seeded From UniProt	complete
involved_in	GO:0031297	replication fork processing	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q08297 ensembl:ENSMUSP00000028795	P	Seeded From UniProt	complete
involved_in	GO:0010833	telomere maintenance via telomere lengthening	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q08297 ensembl:ENSMUSP00000028795	P	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q08297 ensembl:ENSMUSP00000028795	C	Seeded From UniProt	complete
enables	GO:0003697	single-stranded DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q08297 ensembl:ENSMUSP00000028795	F	Seeded From UniProt	complete
enables	GO:0003682	chromatin binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q08297 ensembl:ENSMUSP00000028795	F	Seeded From UniProt	complete
involved_in	GO:0001932	regulation of protein phosphorylation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q08297 ensembl:ENSMUSP00000028795	P	Seeded From UniProt	complete
part_of	GO:0000800	lateral element	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q08297 ensembl:ENSMUSP00000028795	C	Seeded From UniProt	complete
part_of	GO:0000794	condensed nuclear chromosome	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q08297 ensembl:ENSMUSP00000028795	C	Seeded From UniProt	complete
part_of	GO:0000793	condensed chromosome	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q08297 ensembl:ENSMUSP00000028795	C	Seeded From UniProt	complete
part_of	GO:0000784	nuclear chromosome, telomeric region	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q08297 ensembl:ENSMUSP00000028795	C	Seeded From UniProt	complete
involved_in	GO:0000724	double-strand break repair via homologous recombination	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q08297 ensembl:ENSMUSP00000028795	P	Seeded From UniProt	complete
involved_in	GO:0000722	telomere maintenance via recombination	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q08297 ensembl:ENSMUSP00000028795	P	Seeded From UniProt	complete
enables	GO:0000150	recombinase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR011941	F	Seeded From UniProt	complete
enables	GO:0000166	nucleotide binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR010995	F	Seeded From UniProt	complete
involved_in	GO:0000724	double-strand break repair via homologous recombination	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR011941	P	Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR020587 InterPro:IPR020588 InterPro:IPR033925	F	Seeded From UniProt	complete
enables	GO:0003690	double-stranded DNA binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR011941	F	Seeded From UniProt	complete
enables	GO:0003697	single-stranded DNA binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR011941	F	Seeded From UniProt	complete
enables	GO:0005524	ATP binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR020587 InterPro:IPR020588	F	Seeded From UniProt	complete
involved_in	GO:0006259	DNA metabolic process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR020587	P	Seeded From UniProt	complete
involved_in	GO:0006281	DNA repair	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR020588	P	Seeded From UniProt	complete
enables	GO:0008094	DNA-dependent ATPase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR011941 InterPro:IPR020587 InterPro:IPR020588	F	Seeded From UniProt	complete
involved_in	GO:1990426	mitotic recombination-dependent replication fork processing	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR011941	P	Seeded From UniProt	complete
involved_in	GO:0006281	DNA repair	PMID:10422536^[2]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P	Seeded From UniProt	complete
part_of	GO:0005654	nucleoplasm	Reactome:R-GGA-265968 Reactome:R-GGA-265940 Reactome:R-GGA-265862 Reactome:R-GGA-217013	ECO:0000304	author statement supported by traceable reference used in manual assertion		C	Seeded From UniProt	complete
involved_in	GO:0000724	double-strand break repair via homologous recombination	Reactome:R-GGA-351433 Reactome:R-GGA-265976	ECO:0000304	author statement supported by traceable reference used in manual assertion		P	Seeded From UniProt	complete
enables	GO:0005524	ATP binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0067	F	Seeded From UniProt	complete
enables	GO:0000166	nucleotide binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0547	F	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0539 UniProtKB-SubCell:SL-0191	C	Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0238	F	Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 ^1.6 ^1.7 ^1.8 ^1.9 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
↑ Cui, X et al. (1999) The XRCC2 and XRCC3 repair genes are required for chromosome stability in mammalian cells. Mutat. Res. 434 75-88 PubMed GONUTS page

[PMID:21873635-1] 1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 ^1.6 ^1.7 ^1.8 ^1.9 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:10422536-2] Cui, X et al. (1999) The XRCC2 and XRCC3 repair genes are required for chromosome stability in mammalian cells. Mutat. Res. 434 75-88 PubMed GONUTS page

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CHICK:RAD51

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Notes

References

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