CHICK:Q9YGW6

Species (Taxon ID)	Gallus gallus (Chicken). (9031)
Gene Name(s)	EZR (ECO:0000313 with Ensembl:ENSGALP00000022293)
Protein Name(s)	Ezrin (ECO:0000313 with EMBL:BAA75497.1) Uncharacterized protein (ECO:0000313 with Ensembl:ENSGALP00000022293)
External Links
UniProt	Q9YGW6
EMBL	AADN03003294 AB019790
RefSeq	NP_990216.1
UniGene	Gga.40252
SMR	Q9YGW6
STRING	9031.ENSGALP00000022293
PaxDb	Q9YGW6
Ensembl	ENSGALT00000022333
GeneID	395701
KEGG	gga:395701
CTD	7430
eggNOG	NOG236035
GeneTree	ENSGT00760000119078
HOGENOM	HOG000007113
HOVERGEN	HBG002185
KO	K08007
OMA	SEVEEWQ
OrthoDB	EOG7BGHK6
PhylomeDB	Q9YGW6
TreeFam	TF313935
Reactome	REACT_262678
NextBio	20815771
Proteomes	UP000000539
GO	GO:0015629 GO:0005884 GO:0016324 GO:0036064 GO:0005829 GO:0005615 GO:0070062 GO:0019898 GO:0030175 GO:0005925 GO:0005902 GO:0005730 GO:0001726 GO:0001931 GO:0051015 GO:0050839 GO:0044822 GO:0051017 GO:0061028 GO:0035088 GO:0007159 GO:0022614 GO:0010628 GO:0031623
Gene3D	1.20.80.10 2.30.29.30
InterPro	IPR019749 IPR011174 IPR011259 IPR000798 IPR014352 IPR019748 IPR019747 IPR000299 IPR018979 IPR018980 IPR008954 IPR011993 IPR029071
Pfam	PF00769 PF09380 PF00373 PF09379
PIRSF	PIRSF002305
PRINTS	PR00935 PR00661
SMART	SM00295
SUPFAM	SSF47031 SSF48678 SSF54236
PROSITE	PS00660 PS00661 PS50057

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
enables	GO:0050839	cell adhesion molecule binding	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P15311	F		Seeded From UniProt	complete
involved_in	GO:0051017	actin filament bundle assembly	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P15311	P		Seeded From UniProt	complete
enables	GO:0051015	actin filament binding	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P15311	F		Seeded From UniProt	complete
part_of	GO:0019898	extrinsic component of membrane	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P15311	C		Seeded From UniProt	complete
part_of	GO:0015629	actin cytoskeleton	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P15311	C		Seeded From UniProt	complete
part_of	GO:0005884	actin filament	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P15311	C		Seeded From UniProt	complete
involved_in	GO:2000643	positive regulation of early endosome to late endosome transport	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15311 ensembl:ENSP00000356042	P		Seeded From UniProt	complete
involved_in	GO:1903753	negative regulation of p38MAPK cascade	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15311 ensembl:ENSP00000356042	P		Seeded From UniProt	complete
involved_in	GO:1903364	positive regulation of cellular protein catabolic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15311 ensembl:ENSP00000356042	P		Seeded From UniProt	complete
involved_in	GO:1902966	positive regulation of protein localization to early endosome	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15311 ensembl:ENSP00000356042	P		Seeded From UniProt	complete
involved_in	GO:1902115	regulation of organelle assembly	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15311 ensembl:ENSP00000356042	P		Seeded From UniProt	complete
involved_in	GO:1900041	negative regulation of interleukin-2 secretion	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15311 ensembl:ENSP00000356042	P		Seeded From UniProt	complete
part_of	GO:0098592	cytoplasmic side of apical plasma membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15311 ensembl:ENSP00000356042	C		Seeded From UniProt	complete
involved_in	GO:0072697	protein localization to cell cortex	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15311 ensembl:ENSP00000356042	P		Seeded From UniProt	complete
involved_in	GO:0072659	protein localization to plasma membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15311 ensembl:ENSP00000356042	P		Seeded From UniProt	complete
part_of	GO:0071944	cell periphery	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15311 ensembl:ENSP00000356042	C		Seeded From UniProt	complete
part_of	GO:0071437	invadopodium	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15311 ensembl:ENSP00000356042	C		Seeded From UniProt	complete
involved_in	GO:0071320	cellular response to cAMP	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15311 ensembl:ENSP00000356042	P		Seeded From UniProt	complete
involved_in	GO:0070373	negative regulation of ERK1 and ERK2 cascade	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15311 ensembl:ENSP00000356042	P		Seeded From UniProt	complete
involved_in	GO:0061028	establishment of endothelial barrier	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15311 ensembl:ENSP00000356042	P		Seeded From UniProt	complete
involved_in	GO:0051660	establishment of centrosome localization	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15311 ensembl:ENSP00000356042	P		Seeded From UniProt	complete
enables	GO:0051117	ATPase binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15311 ensembl:ENSP00000356042	F		Seeded From UniProt	complete
enables	GO:0051018	protein kinase A binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15311 ensembl:ENSP00000356042	F		Seeded From UniProt	complete
involved_in	GO:0051017	actin filament bundle assembly	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15311 ensembl:ENSP00000356042	P		Seeded From UniProt	complete
enables	GO:0051015	actin filament binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15311 ensembl:ENSP00000356042	F		Seeded From UniProt	complete
involved_in	GO:0050860	negative regulation of T cell receptor signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15311 ensembl:ENSP00000356042	P		Seeded From UniProt	complete
enables	GO:0050839	cell adhesion molecule binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15311 ensembl:ENSP00000356042	F		Seeded From UniProt	complete
involved_in	GO:0050714	positive regulation of protein secretion	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15311 ensembl:ENSP00000356042	P		Seeded From UniProt	complete
part_of	GO:0048471	perinuclear region of cytoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15311 ensembl:ENSP00000356042	C		Seeded From UniProt	complete
involved_in	GO:0048015	phosphatidylinositol-mediated signaling	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15311 ensembl:ENSP00000356042	P		Seeded From UniProt	complete
involved_in	GO:0046847	filopodium assembly	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15311 ensembl:ENSP00000356042	P		Seeded From UniProt	complete
part_of	GO:0045177	apical part of cell	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15311 ensembl:ENSP00000356042	C		Seeded From UniProt	complete
part_of	GO:0044853	plasma membrane raft	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15311 ensembl:ENSP00000356042	C		Seeded From UniProt	complete
enables	GO:0044548	S100 protein binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15311 ensembl:ENSP00000356042	F		Seeded From UniProt	complete
involved_in	GO:0043622	cortical microtubule organization	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15311 ensembl:ENSP00000356042	P		Seeded From UniProt	complete
part_of	GO:0042995	cell projection	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15311 ensembl:ENSP00000356042	C		Seeded From UniProt	complete
enables	GO:0042802	identical protein binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15311 ensembl:ENSP00000356042	F		Seeded From UniProt	complete
involved_in	GO:0034629	cellular protein-containing complex localization	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15311 ensembl:ENSP00000356042	P		Seeded From UniProt	complete
enables	GO:0034237	protein kinase A regulatory subunit binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15311 ensembl:ENSP00000356042	F		Seeded From UniProt	complete
enables	GO:0034236	protein kinase A catalytic subunit binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15311 ensembl:ENSP00000356042	F		Seeded From UniProt	complete
part_of	GO:0032991	protein-containing complex	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15311 ensembl:ENSP00000356042	C		Seeded From UniProt	complete
involved_in	GO:0031532	actin cytoskeleton reorganization	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15311 ensembl:ENSP00000356042	P		Seeded From UniProt	complete
involved_in	GO:0030953	astral microtubule organization	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15311 ensembl:ENSP00000356042	P		Seeded From UniProt	complete
part_of	GO:0030175	filopodium	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15311 ensembl:ENSP00000356042	C		Seeded From UniProt	complete
involved_in	GO:0030033	microvillus assembly	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15311 ensembl:ENSP00000356042	P		Seeded From UniProt	complete
involved_in	GO:0022614	membrane to membrane docking	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15311 ensembl:ENSP00000356042	P		Seeded From UniProt	complete
enables	GO:0019904	protein domain specific binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15311 ensembl:ENSP00000356042	F		Seeded From UniProt	complete
part_of	GO:0019898	extrinsic component of membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15311 ensembl:ENSP00000356042	C		Seeded From UniProt	complete
part_of	GO:0016324	apical plasma membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15311 ensembl:ENSP00000356042	C		Seeded From UniProt	complete
part_of	GO:0015629	actin cytoskeleton	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15311 ensembl:ENSP00000356042	C		Seeded From UniProt	complete
involved_in	GO:0010737	protein kinase A signaling	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15311 ensembl:ENSP00000356042	P		Seeded From UniProt	complete
involved_in	GO:0010628	positive regulation of gene expression	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15311 ensembl:ENSP00000356042	P		Seeded From UniProt	complete
involved_in	GO:0008360	regulation of cell shape	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15311 ensembl:ENSP00000356042	P		Seeded From UniProt	complete
enables	GO:0008017	microtubule binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15311 ensembl:ENSP00000356042	F		Seeded From UniProt	complete
involved_in	GO:0007159	leukocyte cell-cell adhesion	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15311 ensembl:ENSP00000356042	P		Seeded From UniProt	complete
part_of	GO:0005925	focal adhesion	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15311 ensembl:ENSP00000356042	C		Seeded From UniProt	complete
part_of	GO:0005902	microvillus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15311 ensembl:ENSP00000356042	C		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15311 ensembl:ENSP00000356042	C		Seeded From UniProt	complete
part_of	GO:0005884	actin filament	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15311 ensembl:ENSP00000356042	C		Seeded From UniProt	complete
part_of	GO:0005829	cytosol	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15311 ensembl:ENSP00000356042	C		Seeded From UniProt	complete
part_of	GO:0005768	endosome	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15311 ensembl:ENSP00000356042	C		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15311 ensembl:ENSP00000356042	C		Seeded From UniProt	complete
enables	GO:0003779	actin binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15311 ensembl:ENSP00000356042	F		Seeded From UniProt	complete
involved_in	GO:0003376	sphingosine-1-phosphate receptor signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15311 ensembl:ENSP00000356042	P		Seeded From UniProt	complete
part_of	GO:0001772	immunological synapse	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15311 ensembl:ENSP00000356042	C		Seeded From UniProt	complete
part_of	GO:0001726	ruffle	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15311 ensembl:ENSP00000356042	C		Seeded From UniProt	complete
part_of	GO:0001650	fibrillar center	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15311 ensembl:ENSP00000356042	C		Seeded From UniProt	complete
involved_in	GO:0000122	negative regulation of transcription by RNA polymerase II	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15311 ensembl:ENSP00000356042	P		Seeded From UniProt	complete
involved_in	GO:1903078	positive regulation of protein localization to plasma membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P26040 ensembl:ENSMUSP00000063734	P		Seeded From UniProt	complete
involved_in	GO:1902896	terminal web assembly	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P26040 ensembl:ENSMUSP00000063734	P		Seeded From UniProt	complete
enables	GO:0097718	disordered domain specific binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P26040 ensembl:ENSMUSP00000063734	F		Seeded From UniProt	complete
part_of	GO:0045177	apical part of cell	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P26040 ensembl:ENSMUSP00000063734	C		Seeded From UniProt	complete
involved_in	GO:0040018	positive regulation of multicellular organism growth	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P26040 ensembl:ENSMUSP00000063734	P		Seeded From UniProt	complete
part_of	GO:0036064	ciliary basal body	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P26040 ensembl:ENSMUSP00000063734	C		Seeded From UniProt	complete
involved_in	GO:0035088	establishment or maintenance of apical/basal cell polarity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P26040 ensembl:ENSMUSP00000063734	P		Seeded From UniProt	complete
involved_in	GO:0032532	regulation of microvillus length	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P26040 ensembl:ENSMUSP00000063734	P		Seeded From UniProt	complete
involved_in	GO:0031623	receptor internalization	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P26040 ensembl:ENSMUSP00000063734	P		Seeded From UniProt	complete
part_of	GO:0016324	apical plasma membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P26040 ensembl:ENSMUSP00000063734	C		Seeded From UniProt	complete
enables	GO:0008022	protein C-terminus binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P26040 ensembl:ENSMUSP00000063734	F		Seeded From UniProt	complete
part_of	GO:0005903	brush border	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P26040 ensembl:ENSMUSP00000063734	C		Seeded From UniProt	complete
part_of	GO:0005902	microvillus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P26040 ensembl:ENSMUSP00000063734	C		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P26040 ensembl:ENSMUSP00000063734	C		Seeded From UniProt	complete
involved_in	GO:0001951	intestinal D-glucose absorption	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P26040 ensembl:ENSMUSP00000063734	P		Seeded From UniProt	complete
part_of	GO:0001931	uropod	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P26040 ensembl:ENSMUSP00000063734	C		Seeded From UniProt	complete
enables	GO:0003779	actin binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR008954 InterPro:IPR011174	F		Seeded From UniProt	complete
part_of	GO:0005856	cytoskeleton	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000299	C		Seeded From UniProt	complete
enables	GO:0008092	cytoskeletal protein binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000798	F		Seeded From UniProt	complete
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References

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