CHICK:Q9PU40

Species (Taxon ID)	Gallus gallus (Chicken). (9031)
Gene Name(s)	tyrosine hydroxylase (ECO:0000313 with EMBL:CAB62388.1)
Protein Name(s)	Tyrosine hydroxylase (ECO:0000313 with EMBL:CAB62388.1)
External Links
UniProt	Q9PU40
EMBL	AJ251387
PIR	S40309
RefSeq	NP_990136.1
UniGene	Gga.327
ProteinModelPortal	Q9PU40
SMR	Q9PU40
STRING	9031.ENSGALP00000010566
GeneID	395592
KEGG	gga:395592
CTD	7054
eggNOG	COG3186
HOGENOM	HOG000233373
HOVERGEN	HBG006841
InParanoid	Q9PU40
KO	K00501
OrthoDB	EOG7KM5T1
PhylomeDB	Q9PU40
TreeFam	TF313327
Reactome	REACT_248774
NextBio	20815665
PRO	PR:Q9PU40
GO	GO:0030424 GO:0009898 GO:0033162 GO:0005634 GO:0043204 GO:0005790 GO:0005506 GO:0004511 GO:0009072 GO:0042416 GO:0042755 GO:0048596 GO:0042418 GO:0042462 GO:0007507 GO:0007612 GO:0007626 GO:0007617 GO:0007613 GO:0042421 GO:0008016 GO:0045471 GO:0001666 GO:0001963 GO:0007601
Gene3D	1.10.800.10
InterPro	IPR001273 IPR018301 IPR019774 IPR005962 IPR019773 IPR021164
PANTHER	PTHR11473
Pfam	PF00351 PF12549
PIRSF	PIRSF000336
PRINTS	PR00372
SUPFAM	SSF56534
TIGRFAMs	TIGR01269
PROSITE	PS00367 PS51410

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
part_of	GO:0005737	cytoplasm	PMID:20634527^[1]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(UBERON:0001236)	Seeded From UniProt	complete
part_of	GO:0005623	cell	PMID:2572359^[2]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(UBERON:0000955)	Seeded From UniProt	complete
involved_in	GO:0060416	response to growth hormone	PMID:2572359^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	occurs_in:(UBERON:0000955)	Seeded From UniProt	complete
enables	GO:0004511	tyrosine 3-monooxygenase activity	PMID:2572359^[2]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
part_of	GO:0005623	cell	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:H0ZG94	C	part_of:(UBERON:0002035) part_of:(UBERON:0001880) part_of:(UBERON:0001935) part_of:(UBERON:0002691) part_of:(UBERON:0000935) part_of:(UBERON:0002038)	Seeded From UniProt	complete
involved_in	GO:0071625	vocalization behavior	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:H0ZG94	P		Seeded From UniProt	complete
involved_in	GO:0051705	multi-organism behavior	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:H0ZG94	P		Seeded From UniProt	complete
involved_in	GO:0035176	social behavior	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:H0ZG94	P		Seeded From UniProt	complete
involved_in	GO:0007625	grooming behavior	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:H0ZG94	P		Seeded From UniProt	complete
involved_in	GO:0007619	courtship behavior	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:H0ZG94	P		Seeded From UniProt	complete
part_of	GO:0043204	perikaryon	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:98735 PANTHER:PTN000158532 RGD:3853	C		Seeded From UniProt	complete
part_of	GO:0030424	axon	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:98735 PANTHER:PTN000158532 RGD:3853 WB:WBGene00000296	C		Seeded From UniProt	complete
involved_in	GO:0006585	dopamine biosynthetic process from tyrosine	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:98735 PANTHER:PTN001690342 RGD:3853	P		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:98735 PANTHER:PTN000158532 RGD:3853 UniProtKB:P07101 UniProtKB:Q9PU40	C		Seeded From UniProt	complete
enables	GO:0004511	tyrosine 3-monooxygenase activity	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000158532 RGD:3853 UniProtKB:P07101 UniProtKB:Q9PU40 WB:WBGene00000296 ZFIN:ZDB-GENE-990621-5	F		Seeded From UniProt	complete
involved_in	GO:0045471	response to ethanol	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07101 ensembl:ENSP00000370571	P		Seeded From UniProt	complete
part_of	GO:0043005	neuron projection	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07101 ensembl:ENSP00000370571	C		Seeded From UniProt	complete
involved_in	GO:0042421	norepinephrine biosynthetic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07101 ensembl:ENSP00000370571	P		Seeded From UniProt	complete
involved_in	GO:0042418	epinephrine biosynthetic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07101 ensembl:ENSP00000370571	P		Seeded From UniProt	complete
involved_in	GO:0042416	dopamine biosynthetic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07101 ensembl:ENSP00000370571	P		Seeded From UniProt	complete
part_of	GO:0033162	melanosome membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07101 ensembl:ENSP00000370571	C		Seeded From UniProt	complete
part_of	GO:0031410	cytoplasmic vesicle	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07101 ensembl:ENSP00000370571	C		Seeded From UniProt	complete
enables	GO:0019899	enzyme binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07101 ensembl:ENSP00000370571	F		Seeded From UniProt	complete
part_of	GO:0009898	cytoplasmic side of plasma membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07101 ensembl:ENSP00000370571	C		Seeded From UniProt	complete
part_of	GO:0005790	smooth endoplasmic reticulum	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07101 ensembl:ENSP00000370571	C		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07101 ensembl:ENSP00000370571	C		Seeded From UniProt	complete
enables	GO:0004511	tyrosine 3-monooxygenase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07101 ensembl:ENSP00000370571	F		Seeded From UniProt	complete
involved_in	GO:0001666	response to hypoxia	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07101 ensembl:ENSP00000370571	P		Seeded From UniProt	complete
involved_in	GO:0048596	embryonic camera-type eye morphogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P24529 ensembl:ENSMUSP00000000219	P		Seeded From UniProt	complete
part_of	GO:0043204	perikaryon	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P24529 ensembl:ENSMUSP00000000219	C		Seeded From UniProt	complete
part_of	GO:0043005	neuron projection	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P24529 ensembl:ENSMUSP00000000219	C		Seeded From UniProt	complete
involved_in	GO:0042755	eating behavior	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P24529 ensembl:ENSMUSP00000000219	P		Seeded From UniProt	complete
involved_in	GO:0042462	eye photoreceptor cell development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P24529 ensembl:ENSMUSP00000000219	P		Seeded From UniProt	complete
part_of	GO:0030424	axon	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P24529 ensembl:ENSMUSP00000000219	C		Seeded From UniProt	complete
involved_in	GO:0009887	animal organ morphogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P24529 ensembl:ENSMUSP00000000219	P		Seeded From UniProt	complete
involved_in	GO:0008016	regulation of heart contraction	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P24529 ensembl:ENSMUSP00000000219	P		Seeded From UniProt	complete
involved_in	GO:0007626	locomotory behavior	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P24529 ensembl:ENSMUSP00000000219	P		Seeded From UniProt	complete
involved_in	GO:0007617	mating behavior	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P24529 ensembl:ENSMUSP00000000219	P		Seeded From UniProt	complete
involved_in	GO:0007613	memory	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P24529 ensembl:ENSMUSP00000000219	P		Seeded From UniProt	complete
involved_in	GO:0007612	learning	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P24529 ensembl:ENSMUSP00000000219	P		Seeded From UniProt	complete
involved_in	GO:0007601	visual perception	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P24529 ensembl:ENSMUSP00000000219	P		Seeded From UniProt	complete
involved_in	GO:0007507	heart development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P24529 ensembl:ENSMUSP00000000219	P		Seeded From UniProt	complete
involved_in	GO:0006585	dopamine biosynthetic process from tyrosine	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P24529 ensembl:ENSMUSP00000000219	P		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P24529 ensembl:ENSMUSP00000000219	C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P24529 ensembl:ENSMUSP00000000219	C		Seeded From UniProt	complete
involved_in	GO:0001963	synaptic transmission, dopaminergic	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P24529 ensembl:ENSMUSP00000000219	P		Seeded From UniProt	complete
enables	GO:0004497	monooxygenase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001273 InterPro:IPR018301 InterPro:IPR036951	F		Seeded From UniProt	complete
enables	GO:0004511	tyrosine 3-monooxygenase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR005962 InterPro:IPR021164	F		Seeded From UniProt	complete
enables	GO:0005506	iron ion binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001273 InterPro:IPR018301 InterPro:IPR036951	F		Seeded From UniProt	complete
involved_in	GO:0009072	aromatic amino acid family metabolic process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001273 InterPro:IPR018301 InterPro:IPR036951	P		Seeded From UniProt	complete
enables	GO:0016714	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR019773 InterPro:IPR019774	F		Seeded From UniProt	complete
involved_in	GO:0042423	catecholamine biosynthetic process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR005962	P		Seeded From UniProt	complete
involved_in	GO:0055114	oxidation-reduction process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001273 InterPro:IPR005962 InterPro:IPR018301 InterPro:IPR019773 InterPro:IPR019774 InterPro:IPR021164 InterPro:IPR036951	P		Seeded From UniProt	complete
enables	GO:0046872	metal ion binding	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0479	F		Seeded From UniProt	complete
edit table

Notes

References

See Help:References for how to manage references in GONUTS.

↑ Kober, AK et al. (2010) Immunohistochemical localization of catecholamine biosynthetic enzymes in the adrenal gland of the domestic fowl (Gallus domesticus). Poult. Sci. 89 1709-15 PubMed GONUTS page
↑ ^2.0 ^2.1 ^2.2 Kentroti, S & Vernadakis, A (1989) Growth hormone-releasing hormone influences neuronal expression in the developing chick brain. I. Catecholaminergic neurons. Brain Res. Dev. Brain Res. 49 275-80 PubMed GONUTS page
↑ ^3.0 ^3.1 ^3.2 ^3.3 ^3.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:20634527-1] Kober, AK et al. (2010) Immunohistochemical localization of catecholamine biosynthetic enzymes in the adrenal gland of the domestic fowl (Gallus domesticus). Poult. Sci. 89 1709-15 PubMed GONUTS page

[PMID:2572359-2] 2.0 ^2.1 ^2.2 Kentroti, S & Vernadakis, A (1989) Growth hormone-releasing hormone influences neuronal expression in the developing chick brain. I. Catecholaminergic neurons. Brain Res. Dev. Brain Res. 49 275-80 PubMed GONUTS page

[PMID:21873635-3] 3.0 ^3.1 ^3.2 ^3.3 ^3.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[1]

[2]

[3]

CHICK:Q9PU40

Contents

Annotations

Notes

References

a

c

d

e

g

h

i

l

m

n

o

p

r

s

t

v

Navigation menu

Personal tools

Namespaces

Variants

Views

More

Search

Navigation

Cacao

Links

Tools