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CHICK:Q9DFH3
Contents
| Species (Taxon ID) | Gallus gallus (Chicken). (9031) | |
| Gene Name(s) | CXR (ECO:0000313 with EMBL:AAG18374.1) | |
| Protein Name(s) | Xenobiotic receptor (ECO:0000313 with EMBL:AAG18374.1) | |
| External Links | ||
| UniProt | Q9DFH3 | |
| EMBL | AF276753 | |
| RefSeq | NP_990033.1 | |
| UniGene | Gga.237 | |
| ProteinModelPortal | Q9DFH3 | |
| SMR | Q9DFH3 | |
| STRING | 9031.ENSGALP00000035024 | |
| GeneID | 395439 | |
| KEGG | gga:395439 | |
| CTD | 9970 | |
| eggNOG | NOG330028 | |
| HOVERGEN | HBG108655 | |
| KO | K08541 | |
| PhylomeDB | Q9DFH3 | |
| NextBio | 20815523 | |
| GO | GO:0005634 GO:0043565 GO:0003707 GO:0004887 GO:0008270 | |
| Gene3D | 1.10.565.10 3.30.50.10 | |
| InterPro | IPR008946 IPR000536 IPR001723 IPR001728 IPR001628 IPR013088 | |
| Pfam | PF00104 PF00105 | |
| PRINTS | PR00398 PR00047 PR00546 | |
| SMART | SM00430 SM00399 | |
| SUPFAM | SSF48508 | |
| PROSITE | PS00031 PS51030 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
involved_in |
GO:0010628 |
positive regulation of gene expression |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005667 |
transcription factor complex |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0001158 |
enhancer sequence-specific DNA binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0042493 |
response to drug |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
has_participant:(CHEBI:8069)|has_participant:(CHEBI:5439)|has_participant:(CHEBI:44241)|has_participant:(CHEBI:3764)|has_participant:(CHEBI:77013) |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:2000144 |
positive regulation of DNA-templated transcription, initiation |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0042493 |
response to drug |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0001158 |
enhancer sequence-specific DNA binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0010628 |
positive regulation of gene expression |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0043565 |
sequence-specific DNA binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0030522 |
intracellular receptor signaling pathway |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0004879 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0043401 |
steroid hormone mediated signaling pathway |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0003707 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003700 |
DNA-binding transcription factor activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003707 |
steroid hormone receptor activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004879 |
nuclear receptor activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006355 |
regulation of transcription, DNA-templated |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR001628 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0008270 |
zinc ion binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0043565 |
sequence-specific DNA binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0046872 |
metal ion binding |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 Handschin, C et al. (2001) Conservation of signaling pathways of xenobiotic-sensing orphan nuclear receptors, chicken xenobiotic receptor, constitutive androstane receptor, and pregnane X receptor, from birds to humans. Mol. Endocrinol. 15 1571-85 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Handschin, C et al. (2000) CXR, a chicken xenobiotic-sensing orphan nuclear receptor, is related to both mammalian pregnane X receptor (PXR) and constitutive androstane receptor (CAR). Proc. Natl. Acad. Sci. U.S.A. 97 10769-74 PubMed GONUTS page
- ↑ 3.0 3.1 Baader, M et al. (2002) Transcriptional activation of cytochrome P450 CYP2C45 by drugs is mediated by the chicken xenobiotic receptor (CXR) interacting with a phenobarbital response enhancer unit. J. Biol. Chem. 277 15647-53 PubMed GONUTS page
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