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CHICK:Q70IK3

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) TCF3 (ECO:0000313 with Ensembl:ENSGALP00000001635)
Protein Name(s) Helix-loop-helix protein E12 (ECO:0000313 with EMBL:CAE30453.2)

Uncharacterized protein (ECO:0000313 with Ensembl:ENSGALP00000001635)

External Links
UniProt Q70IK3
EMBL AADN03008887
AADN03009009
AJ579995
RefSeq NP_989817.2
UniGene Gga.41918
STRING 9031.ENSGALP00000001635
Ensembl ENSGALT00000001637
GeneID 395146
KEGG gga:395146
CTD 6929
GeneTree ENSGT00510000046438
HOGENOM HOG000234180
HOVERGEN HBG003854
KO K09063
OMA MHSGEVN
OrthoDB EOG72G16Q
PhylomeDB Q70IK3
TreeFam TF321672
Reactome REACT_244114
NextBio 20815238
PRO PR:Q70IK3
Proteomes UP000000539
GO GO:0005737
GO:0000788
GO:0005667
GO:0003682
GO:0070888
GO:0046982
GO:0000978
GO:0001078
GO:0003713
GO:0070644
GO:0048468
GO:0043966
GO:0043967
GO:0033152
GO:0001779
GO:0048541
GO:0030890
GO:0045787
GO:0051091
GO:0045944
GO:0050821
GO:2000045
GO:0042493
GO:0032496
GO:0033077
Gene3D 4.10.280.10
InterPro IPR011598
Pfam PF00010
SMART SM00353
SUPFAM SSF47459
PROSITE PS50888

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

part_of

GO:0090575

RNA polymerase II transcription factor complex

PMID:8035824[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

contributes_to

GO:0070888

E-box binding

PMID:8035824[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0046982

protein heterodimerization activity

PMID:8035824[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0005667

transcription factor complex

PMID:8035824[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0046982

protein heterodimerization activity

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0267821
MGI:MGI:101877
MGI:MGI:98506
MGI:MGI:98510
PANTHER:PTN000927455
UniProtKB:P15923
UniProtKB:Q70IK3
WB:WBGene00001949

F

Seeded From UniProt

complete

involved_in

GO:0045944

positive regulation of transcription by RNA polymerase II

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0267821
MGI:MGI:98506
MGI:MGI:98510
PANTHER:PTN000927455
RGD:3829
RGD:69271
UniProtKB:P15923
UniProtKB:Q99081
WB:WBGene00001949

P

Seeded From UniProt

complete

involved_in

GO:0045666

positive regulation of neuron differentiation

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:101877
MGI:MGI:98506
MGI:MGI:98510
PANTHER:PTN000927455

P

Seeded From UniProt

complete

enables

GO:0043425

bHLH transcription factor binding

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000927455
RGD:620914
RGD:69271
UniProtKB:P15923
UniProtKB:Q99081
WB:WBGene00001949

F

Seeded From UniProt

complete

enables

GO:0042803

protein homodimerization activity

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0267821
MGI:MGI:98510
PANTHER:PTN000927455
UniProtKB:P15923
WB:WBGene00001949

F

Seeded From UniProt

complete

part_of

GO:0005667

transcription factor complex

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0267821
MGI:MGI:101877
MGI:MGI:98506
MGI:MGI:98510
PANTHER:PTN000927455
RGD:620914
UniProtKB:P15923
UniProtKB:Q70IK3

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0267821
MGI:MGI:98506
MGI:MGI:98510
PANTHER:PTN000927455
RGD:3829
UniProtKB:P15884
UniProtKB:P15923
UniProtKB:Q99081
WB:WBGene00001949

C

Seeded From UniProt

complete

enables

GO:0003700

DNA-binding transcription factor activity

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0267821
MGI:MGI:98510
PANTHER:PTN000927455
UniProtKB:P15884
UniProtKB:P15923
UniProtKB:Q99081

F

Seeded From UniProt

complete

enables

GO:0000978

RNA polymerase II proximal promoter sequence-specific DNA binding

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:98506
MGI:MGI:98510
PANTHER:PTN000927455
UniProtKB:P15884
UniProtKB:P15923
UniProtKB:Q99081

F

Seeded From UniProt

complete

enables

GO:0046983

protein dimerization activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR011598
InterPro:IPR036638

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 Dechesne, CA et al. (1994) E-box- and MEF-2-independent muscle-specific expression, positive autoregulation, and cross-activation of the chicken MyoD (CMD1) promoter reveal an indirect regulatory pathway. Mol. Cell. Biol. 14 5474-86 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 2.8 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page