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CHICK:Q5F3W0

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) CARD11 (ECO:0000313 with Ensembl:ENSGALP00000007002)
Protein Name(s) Uncharacterized protein (ECO:0000313 with Ensembl:ENSGALP00000007002)
External Links
UniProt Q5F3W0
EMBL AADN03006858
AJ851540
RefSeq NP_001006161.2
UniGene Gga.7057
IntAct Q5F3W0
STRING 9031.ENSGALP00000007002
Ensembl ENSGALT00000007013
GeneID 416476
KEGG gga:416476
CTD 84433
eggNOG NOG47732
GeneTree ENSGT00530000063108
HOGENOM HOG000111299
HOVERGEN HBG099790
KO K07367
OMA AKNKHCL
OrthoDB EOG747PH5
PhylomeDB Q5F3W0
TreeFam TF351139
Reactome REACT_197120
REACT_197909
REACT_250045
NextBio 20819923
PRO PR:Q5F3W0
Proteomes UP000000539
GO GO:0005737
GO:0001772
GO:0045121
GO:0005886
GO:0042101
GO:0030890
GO:0043123
GO:0045086
GO:0051092
GO:0042102
GO:0042981
GO:0045577
GO:0050776
GO:0045580
GO:0007165
GO:0031295
GO:0045061
Gene3D 1.10.533.10
2.30.42.10
3.40.50.300
InterPro IPR001315
IPR011029
IPR027417
IPR001478
Pfam PF00619
PF00595
SMART SM00228
SUPFAM SSF47986
SSF50156
SSF52540
PROSITE PS50209
PS50106

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0042976

activation of Janus kinase activity

PMID:18086859[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0007250

activation of NF-kappaB-inducing kinase activity

PMID:18086859[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0032991

protein-containing complex

PMID:18086859[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0043123

positive regulation of I-kappaB kinase/NF-kappaB signaling

PMID:16301747[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0000185

activation of MAPKKK activity

PMID:16301747[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0089720

caspase binding

PMID:16301747[2]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:A0A1D5P1T2

F

occurs_in:(CL:0000236)

Seeded From UniProt

complete

enables

GO:0031435

mitogen-activated protein kinase kinase kinase binding

PMID:16301747[2]

ECO:0000314

direct assay evidence used in manual assertion

F

occurs_in:(CL:0000236)

Seeded From UniProt

complete

involved_in

GO:0050853

B cell receptor signaling pathway

PMID:16301747[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

occurs_in:(CL:0000236)

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

PMID:18086859[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0070970

interleukin-2 secretion

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8CIS0
ensembl:ENSMUSP00000082941

P

Seeded From UniProt

complete

involved_in

GO:0050870

positive regulation of T cell activation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8CIS0
ensembl:ENSMUSP00000082941

P

Seeded From UniProt

complete

involved_in

GO:0050776

regulation of immune response

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8CIS0
ensembl:ENSMUSP00000082941

P

Seeded From UniProt

complete

involved_in

GO:0048872

homeostasis of number of cells

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8CIS0
ensembl:ENSMUSP00000082941

P

Seeded From UniProt

complete

involved_in

GO:0046649

lymphocyte activation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8CIS0
ensembl:ENSMUSP00000082941

P

Seeded From UniProt

complete

involved_in

GO:0045580

regulation of T cell differentiation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8CIS0
ensembl:ENSMUSP00000082941

P

Seeded From UniProt

complete

involved_in

GO:0045577

regulation of B cell differentiation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8CIS0
ensembl:ENSMUSP00000082941

P

Seeded From UniProt

complete

involved_in

GO:0045086

positive regulation of interleukin-2 biosynthetic process

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8CIS0
ensembl:ENSMUSP00000082941

P

Seeded From UniProt

complete

involved_in

GO:0045061

thymic T cell selection

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8CIS0
ensembl:ENSMUSP00000082941

P

Seeded From UniProt

complete

involved_in

GO:0043123

positive regulation of I-kappaB kinase/NF-kappaB signaling

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8CIS0
ensembl:ENSMUSP00000082941

P

Seeded From UniProt

complete

involved_in

GO:0042110

T cell activation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8CIS0
ensembl:ENSMUSP00000082941

P

Seeded From UniProt

complete

involved_in

GO:0042102

positive regulation of T cell proliferation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8CIS0
ensembl:ENSMUSP00000082941

P

Seeded From UniProt

complete

involved_in

GO:0042100

B cell proliferation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8CIS0
ensembl:ENSMUSP00000082941

P

Seeded From UniProt

complete

involved_in

GO:0030890

positive regulation of B cell proliferation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8CIS0
ensembl:ENSMUSP00000082941

P

Seeded From UniProt

complete

involved_in

GO:0030183

B cell differentiation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8CIS0
ensembl:ENSMUSP00000082941

P

Seeded From UniProt

complete

involved_in

GO:0007165

signal transduction

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8CIS0
ensembl:ENSMUSP00000082941

P

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8CIS0
ensembl:ENSMUSP00000082941

C

Seeded From UniProt

complete

involved_in

GO:0002377

immunoglobulin production

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8CIS0
ensembl:ENSMUSP00000082941

P

Seeded From UniProt

complete

part_of

GO:0001772

immunological synapse

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8CIS0
ensembl:ENSMUSP00000082941

C

Seeded From UniProt

complete

involved_in

GO:0051092

positive regulation of NF-kappaB transcription factor activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9BXL7
ensembl:ENSP00000380150

P

Seeded From UniProt

complete

enables

GO:0050700

CARD domain binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9BXL7
ensembl:ENSP00000380150

F

Seeded From UniProt

complete

part_of

GO:0045121

membrane raft

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9BXL7
ensembl:ENSP00000380150

C

Seeded From UniProt

complete

involved_in

GO:0038202

TORC1 signaling

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9BXL7
ensembl:ENSP00000380150

P

Seeded From UniProt

complete

part_of

GO:0032449

CBM complex

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9BXL7
ensembl:ENSP00000380150

C

Seeded From UniProt

complete

involved_in

GO:0031295

T cell costimulation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9BXL7
ensembl:ENSP00000380150

P

Seeded From UniProt

complete

involved_in

GO:0007249

I-kappaB kinase/NF-kappaB signaling

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9BXL7
ensembl:ENSP00000380150

P

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9BXL7
ensembl:ENSP00000380150

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9BXL7
ensembl:ENSP00000380150

C

Seeded From UniProt

complete

involved_in

GO:0001819

positive regulation of cytokine production

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9BXL7
ensembl:ENSP00000380150

P

Seeded From UniProt

complete

involved_in

GO:0042981

regulation of apoptotic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001315

P

Seeded From UniProt

complete

involved_in

GO:0051092

positive regulation of NF-kappaB transcription factor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR033538

P

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

Reactome:R-GGA-1169563

ECO:0000304

author statement supported by traceable reference used in manual assertion

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 Shinohara, H et al. (2007) IkappaB kinase beta-induced phosphorylation of CARMA1 contributes to CARMA1 Bcl10 MALT1 complex formation in B cells. J. Exp. Med. 204 3285-93 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 Shinohara, H et al. (2005) PKC beta regulates BCR-mediated IKK activation by facilitating the interaction between TAK1 and CARMA1. J. Exp. Med. 202 1423-31 PubMed GONUTS page