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CHICK:Q59J86
Contents
Species (Taxon ID) | Gallus gallus (Chicken). (9031) | |
Gene Name(s) | No Information Provided. | |
Protein Name(s) | DNA polymerase (ECO:0000256 with RuleBase:RU000442) | |
External Links | ||
UniProt | Q59J86 | |
EMBL | AB178529 | |
UniGene | Gga.12097 | |
STRING | 9031.ENSGALP00000026266 | |
PaxDb | Q59J86 | |
eggNOG | COG0417 | |
HOGENOM | HOG000163524 | |
HOVERGEN | HBG080008 | |
PhylomeDB | Q59J86 | |
GO | GO:0005658 GO:0005635 GO:0016363 GO:0005730 GO:0005654 GO:0005634 GO:0003682 GO:0003677 GO:0030337 GO:0003896 GO:0003887 GO:0001882 GO:0000166 GO:0032403 GO:0030154 GO:0008283 GO:0006260 GO:0006270 GO:0006269 GO:0006271 GO:0000731 GO:0006303 GO:0006273 GO:0006272 GO:0006298 GO:0045596 GO:0046677 | |
Gene3D | 3.30.420.10 3.90.1600.10 | |
InterPro | IPR006172 IPR017964 IPR006133 IPR006134 IPR024647 IPR023211 IPR029702 IPR012337 IPR015088 | |
PANTHER | PTHR10322:SF18 | |
Pfam | PF12254 PF00136 PF03104 PF08996 | |
PRINTS | PR00106 | |
SMART | SM00486 | |
SUPFAM | SSF53098 | |
PROSITE | PS00116 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
involved_in |
GO:0006261 |
DNA-dependent DNA replication |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0003887 |
DNA-directed DNA polymerase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0044877 |
protein-containing complex binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0005658 |
alpha DNA polymerase:primase complex |
ECO:0000353 |
physical interaction evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0003887 |
DNA-directed DNA polymerase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0003887 |
DNA-directed DNA polymerase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0019899 |
enzyme binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0005658 |
alpha DNA polymerase:primase complex |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0046677 |
response to antibiotic |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0045596 |
negative regulation of cell differentiation |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0044877 |
protein-containing complex binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0030337 |
DNA polymerase processivity factor activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0030154 |
cell differentiation |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006298 |
mismatch repair |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006260 |
DNA replication |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006260 |
DNA replication |
ECO:0000303 |
author statement without traceable support used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0005658 |
alpha DNA polymerase:primase complex |
ECO:0000353 |
physical interaction evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005634 |
nucleus |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005634 |
nucleus |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0003896 |
DNA primase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0003887 |
DNA-directed DNA polymerase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0003887 |
DNA-directed DNA polymerase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0003887 |
DNA-directed DNA polymerase activity |
ECO:0000303 |
author statement without traceable support used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0003677 |
DNA binding |
ECO:0000303 |
author statement without traceable support used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0000731 |
DNA synthesis involved in DNA repair |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0016363 |
nuclear matrix |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0008283 |
cell population proliferation |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006303 |
double-strand break repair via nonhomologous end joining |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
NOT|involved_in |
GO:0006281 |
DNA repair |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006273 |
lagging strand elongation |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006272 |
leading strand elongation |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006271 |
DNA strand elongation involved in DNA replication |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006270 |
DNA replication initiation |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006260 |
DNA replication |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0005730 |
nucleolus |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005658 |
alpha DNA polymerase:primase complex |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005654 |
nucleoplasm |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005635 |
nuclear envelope |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005634 |
nucleus |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006269 |
DNA replication, synthesis of RNA primer |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0003887 |
DNA-directed DNA polymerase activity |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0003682 |
chromatin binding |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0003677 |
DNA binding |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
colocalizes_with |
GO:0000785 |
chromatin |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
NOT|involved_in |
GO:1904161 |
DNA synthesis involved in UV-damage excision repair |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0000166 |
nucleotide binding |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0000166 |
nucleotide binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0001882 |
nucleoside binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0003676 |
nucleic acid binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0003677 |
DNA binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0003887 |
DNA-directed DNA polymerase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006260 |
DNA replication |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0003887 |
DNA-directed DNA polymerase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006260 |
DNA replication |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0003677 |
DNA binding |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0046872 |
metal ion binding |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0016740 |
transferase activity |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0051536 |
iron-sulfur cluster binding |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0016779 |
nucleotidyltransferase activity |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0003887 |
DNA-directed DNA polymerase activity |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0051539 |
4 iron, 4 sulfur cluster binding |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0005634 |
nucleus |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005634 |
nucleus |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 Kunkel, TA (1985) The mutational specificity of DNA polymerases-alpha and -gamma during in vitro DNA synthesis. J. Biol. Chem. 260 12866-74 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Ray, S et al. (1991) Developmental expression of the embryonic chicken brain DNA polymerase alpha and its binding with monoclonal antibodies against human KB cell DNA polymerase alpha. Cell Growth Differ. 2 567-73 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Ray, S et al. (1994) Characterization of DNA polymerase-alpha/primase complex from developing embryonic chicken brains. Indian J. Biochem. Biophys. 31 226-35 PubMed GONUTS page
- ↑ 4.0 4.1 Rusquet, R et al. (1984) Quinolone antibiotics inhibit eucaryotic DNA polymerase alpha and beta, terminal deoxynucleotidyl transferase but not DNA ligase. Biochem. Biophys. Res. Commun. 121 762-9 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 5.3 Matsukage, A et al. (1986) Differentiation of lens and neural cells in chicken embryos is accompanied by simultaneous decay of DNA replication machinery. Dev. Biol. 117 226-32 PubMed GONUTS page
- ↑ 6.0 6.1 6.2 6.3 Hirose, F et al. (1985) Monoclonal antibody specific for chicken DNA polymerase alpha associated with DNA primase. Biochem. Biophys. Res. Commun. 132 210-6 PubMed GONUTS page
- ↑ 7.0 7.1 Kunkel, TA & Alexander, PS (1986) The base substitution fidelity of eucaryotic DNA polymerases. Mispairing frequencies, site preferences, insertion preferences, and base substitution by dislocation. J. Biol. Chem. 261 160-6 PubMed GONUTS page
- ↑ 8.0 8.1 Matsukage, A et al. (1983) Immunocytochemical localization of chick DNA polymerases alpha and beta +. J. Cell. Physiol. 117 266-71 PubMed GONUTS page
- ↑ Yamaguchi, M et al. (1982) Chick embryo DNA polymerase alpha. Polypeptide components and their microheterogeneity. J. Biol. Chem. 257 4484-9 PubMed GONUTS page
c
d
- Dinosauria
- GO:0003887 ! DNA-directed DNA polymerase activity
- GO:0006261 ! DNA-templated DNA replication
- GO:0003677 ! DNA binding
- GO:0030337 ! DNA polymerase processivity factor activity
- GO:0003896 ! DNA primase activity
- GO:0006281 ! DNA repair
- GO:0006270 ! DNA replication initiation
- GO:0006260 ! DNA replication
- GO:0006269 ! DNA replication, synthesis of RNA primer
- GO:0006271 ! DNA strand elongation involved in DNA replication
- GO:1904161 ! DNA synthesis involved in UV-damage excision repair
- GO:0000731 ! DNA synthesis involved in DNA repair
- GO:0006303 ! double-strand break repair via nonhomologous end joining
n
- GO:0045596 ! negative regulation of cell differentiation
- Neognathae
- GO:0005635 ! nuclear envelope
- GO:0016363 ! nuclear matrix
- GO:0003676 ! nucleic acid binding
- GO:0005730 ! nucleolus
- GO:0005654 ! nucleoplasm
- GO:0001882 ! nucleoside binding
- GO:0000166 ! nucleotide binding
- GO:0016779 ! nucleotidyltransferase activity
- GO:0005634 ! nucleus