CHICK:NBN

Species (Taxon ID)	Gallus gallus (Chicken). (9031)
Gene Name(s)	NBN (synonyms: NBS1)
Protein Name(s)	Nibrin Nijmegen breakage syndrome protein 1 homolog
External Links
UniProt	Q9DE07
EMBL	AF230342
RefSeq	NP_989668.1
UniGene	Gga.196
ProteinModelPortal	Q9DE07
SMR	Q9DE07
STRING	9031.ENSGALP00000025599
PaxDb	Q9DE07
GeneID	374246
KEGG	gga:374246
CTD	4683
eggNOG	NOG84999
HOGENOM	HOG000231654
HOVERGEN	HBG053070
InParanoid	Q9DE07
KO	K10867
PhylomeDB	Q9DE07
Reactome	REACT_115539 REACT_115715 REACT_115915
NextBio	20813741
PRO	PR:Q9DE07
Proteomes	UP000000539
GO	GO:0000781 GO:0030870 GO:0042405 GO:0005654 GO:0047485 GO:0008134 GO:0006281 GO:0006302 GO:0000724 GO:0051321 GO:0007093 GO:0007095 GO:0048145 GO:0000723
Gene3D	2.60.200.20 3.40.50.10190
InterPro	IPR001357 IPR013908 IPR000253 IPR016592 IPR008984
Pfam	PF00533 PF00498 PF08599
PIRSF	PIRSF011869
SMART	SM00292 SM00240
SUPFAM	SSF49879 SSF52113
PROSITE	PS50006

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
involved_in	GO:0048145	regulation of fibroblast proliferation	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q9JIL9	P	Seeded From UniProt	complete
enables	GO:0047485	protein N-terminus binding	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:O60934	F	Seeded From UniProt	complete
part_of	GO:0042405	nuclear inclusion body	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:O60934	C	Seeded From UniProt	complete
part_of	GO:0030870	Mre11 complex	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:O60934	C	Seeded From UniProt	complete
enables	GO:0008134	transcription factor binding	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:O60934	F	Seeded From UniProt	complete
involved_in	GO:0007095	mitotic G2 DNA damage checkpoint	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:O60934	P	Seeded From UniProt	complete
involved_in	GO:0007093	mitotic cell cycle checkpoint	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:O60934	P	Seeded From UniProt	complete
involved_in	GO:0006302	double-strand break repair	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:O60934	P	Seeded From UniProt	complete
involved_in	GO:0000723	telomere maintenance	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:O60934	P	Seeded From UniProt	complete
involved_in	GO:0042770	signal transduction in response to DNA damage	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0261530 PANTHER:PTN000255549	P	Seeded From UniProt	complete
involved_in	GO:0032508	DNA duplex unwinding	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000255549 UniProtKB:O60934	P	Seeded From UniProt	complete
part_of	GO:0030870	Mre11 complex	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000255549 PomBase:SPBC6B1.09c UniProtKB:O60934	C	Seeded From UniProt	complete
involved_in	GO:0016233	telomere capping	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0261530 PANTHER:PTN000255549	P	Seeded From UniProt	complete
involved_in	GO:0007095	mitotic G2 DNA damage checkpoint	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0261530 MGI:MGI:1351625 PANTHER:PTN000255549 UniProtKB:O60934	P	Seeded From UniProt	complete
contributes_to	GO:0004003	ATP-dependent DNA helicase activity	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000255549 UniProtKB:O60934	F	Seeded From UniProt	complete
enables	GO:0003684	damaged DNA binding	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1351625 PANTHER:PTN000255549	F	Seeded From UniProt	complete
part_of	GO:0000784	nuclear chromosome, telomeric region	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1351625 PANTHER:PTN000255549 PomBase:SPBC6B1.09c UniProtKB:O60934	C	Seeded From UniProt	complete
involved_in	GO:0000724	double-strand break repair via homologous recombination	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000255549 TAIR:locus:2076934	P	Seeded From UniProt	complete
involved_in	GO:0000723	telomere maintenance	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR016592	P	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR016592	C	Seeded From UniProt	complete
involved_in	GO:0006281	DNA repair	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR016592	P	Seeded From UniProt	complete
involved_in	GO:0006302	double-strand break repair	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR040227	P	Seeded From UniProt	complete
involved_in	GO:0006974	cellular response to DNA damage stimulus	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR016592	P	Seeded From UniProt	complete
involved_in	GO:0007093	mitotic cell cycle checkpoint	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR016592	P	Seeded From UniProt	complete
involved_in	GO:0007095	mitotic G2 DNA damage checkpoint	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR040227	P	Seeded From UniProt	complete
part_of	GO:0030870	Mre11 complex	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR016592 InterPro:IPR040227	C	Seeded From UniProt	complete
involved_in	GO:0006281	DNA repair	Reactome:R-GGA-353377	ECO:0000304	author statement supported by traceable reference used in manual assertion		P	Seeded From UniProt	complete
part_of	GO:0005654	nucleoplasm	Reactome:R-GGA-351456 Reactome:R-GGA-351455 Reactome:R-GGA-351412	ECO:0000304	author statement supported by traceable reference used in manual assertion		C	Seeded From UniProt	complete
involved_in	GO:0000724	double-strand break repair via homologous recombination	Reactome:R-GGA-351444	ECO:0000304	author statement supported by traceable reference used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0006281	DNA repair	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0234	P	Seeded From UniProt	complete
part_of	GO:0005694	chromosome	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0158	C	Seeded From UniProt	complete
involved_in	GO:0006974	cellular response to DNA damage stimulus	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0227	P	Seeded From UniProt	complete
part_of	GO:0000781	chromosome, telomeric region	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0779 UniProtKB-SubCell:SL-0276	C	Seeded From UniProt	complete
involved_in	GO:0007049	cell cycle	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0131	P	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0539 UniProtKB-SubCell:SL-0191	C	Seeded From UniProt	complete
involved_in	GO:0051321	meiotic cell cycle	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0469	P	Seeded From UniProt	complete
edit table

Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 ^1.6 ^1.7 ^1.8 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:21873635-1] 1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 ^1.6 ^1.7 ^1.8 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[1]

CHICK:NBN

Contents

Annotations

Notes

References

a

c

d

e

g

m

n

o

p

r

s

t

v

Navigation menu

Personal tools

Namespaces

Variants

Views

More

Search

Navigation

Cacao

Links

Tools