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CHICK:MRE11

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) MRE11
Protein Name(s) Double-strand break repair protein MRE11
External Links
UniProt Q9IAM7
EMBL AF166094
RefSeq NP_990109.1
UniGene Gga.3157
ProteinModelPortal Q9IAM7
STRING 9031.ENSGALP00000035634
PaxDb Q9IAM7
GeneID 395555
KEGG gga:395555
CTD 4361
eggNOG COG0420
HOGENOM HOG000216581
HOVERGEN HBG052508
InParanoid Q9IAM7
KO K10865
PhylomeDB Q9IAM7
Reactome REACT_115539
REACT_115915
NextBio 20815630
PRO PR:Q9IAM7
Proteomes UP000000539
GO GO:0005654
GO:0004519
GO:0004527
GO:0030145
GO:0006281
GO:0006302
GO:0000724
GO:0051321
Gene3D 3.60.21.10
InterPro IPR004843
IPR003701
IPR029052
IPR007281
PANTHER PTHR10139
Pfam PF00149
PF04152
PIRSF PIRSF000882
SUPFAM SSF56300
TIGRFAMs TIGR00583

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

enables

GO:0008409

5'-3' exonuclease activity

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P49959

F

Seeded From UniProt

complete

involved_in

GO:0110025

DNA strand resection involved in replication fork processing

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P49959

P

Seeded From UniProt

complete

involved_in

GO:0006974

cellular response to DNA damage stimulus

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P49959

P

Seeded From UniProt

complete

involved_in

GO:0000724

double-strand break repair via homologous recombination

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P49959

P

Seeded From UniProt

complete

part_of

GO:0005657

replication fork

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P49959

C

Seeded From UniProt

complete

involved_in

GO:0097552

mitochondrial double-strand break repair via homologous recombination

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000015644
SGD:S000004837

P

Seeded From UniProt

complete

involved_in

GO:0042138

meiotic DNA double-strand break formation

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000015644
PomBase:SPAC13C5.07

P

Seeded From UniProt

complete

involved_in

GO:0031573

intra-S DNA damage checkpoint

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1100512
PANTHER:PTN000015646
PomBase:SPAC13C5.07

P

Seeded From UniProt

complete

enables

GO:0008408

3'-5' exonuclease activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002228124
SGD:S000004837
UniProtKB:P49959

F

Seeded From UniProt

complete

enables

GO:0008296

3'-5'-exodeoxyribonuclease activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002228124
SGD:S000004837

F

Seeded From UniProt

complete

involved_in

GO:0007095

mitotic G2 DNA damage checkpoint

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0020270
MGI:MGI:1100512
PANTHER:PTN000015644

P

Seeded From UniProt

complete

involved_in

GO:0006303

double-strand break repair via nonhomologous end joining

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000015644
PomBase:SPAC13C5.07
SGD:S000004837
UniProtKB:P49959

P

Seeded From UniProt

complete

colocalizes_with

GO:0000784

nuclear chromosome, telomeric region

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1100512
PANTHER:PTN000015644
PomBase:SPAC13C5.07
UniProtKB:P49959

C

Seeded From UniProt

complete

involved_in

GO:0000724

double-strand break repair via homologous recombination

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000015644
PomBase:SPAC13C5.07
SGD:S000004837
UniProtKB:P49959

P

Seeded From UniProt

complete

involved_in

GO:0000723

telomere maintenance

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0020270
PANTHER:PTN000015644
PomBase:SPAC13C5.07
SGD:S000004837
UniProtKB:P49959

P

Seeded From UniProt

complete

enables

GO:0004519

endonuclease activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003701
InterPro:IPR007281

F

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR007281

C

Seeded From UniProt

complete

involved_in

GO:0006302

double-strand break repair

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003701
InterPro:IPR007281

P

Seeded From UniProt

complete

enables

GO:0008408

3'-5' exonuclease activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003701

F

Seeded From UniProt

complete

enables

GO:0016787

hydrolase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004843

F

Seeded From UniProt

complete

enables

GO:0030145

manganese ion binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR007281

F

Seeded From UniProt

complete

part_of

GO:0030870

Mre11 complex

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003701

C

Seeded From UniProt

complete

involved_in

GO:0006281

DNA repair

Reactome:R-GGA-353377

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005654

nucleoplasm

Reactome:R-GGA-351412
Reactome:R-GGA-351407

ECO:0000304

author statement supported by traceable reference used in manual assertion


C

Seeded From UniProt

complete

involved_in

GO:0000724

double-strand break repair via homologous recombination

Reactome:R-GGA-351444

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0016787

hydrolase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0378

F

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

enables

GO:0004519

endonuclease activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0255

F

Seeded From UniProt

complete

enables

GO:0004518

nuclease activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0540

F

Seeded From UniProt

complete

enables

GO:0004527

exonuclease activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0269

F

Seeded From UniProt

complete

involved_in

GO:0051321

meiotic cell cycle

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0469

P

Seeded From UniProt

complete

involved_in

GO:0006281

DNA repair

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0234

P

Seeded From UniProt

complete

involved_in

GO:0006974

cellular response to DNA damage stimulus

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0227

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 1.9 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page