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CHICK:LHX3

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) LHX3 (synonyms: LIM-3, LIM3)
Protein Name(s) LIM/homeobox protein Lhx3

LIM homeobox protein 3 Homeobox protein LIM-3

External Links
UniProt P53412
EMBL L35570
PIR I50376
RefSeq NP_001025506.1
UniGene Gga.91
ProteinModelPortal P53412
SMR P53412
STRING 9031.ENSGALP00000002660
PaxDb P53412
Ensembl ENSGALT00000002663
GeneID 373940
KEGG gga:373940
CTD 8022
eggNOG NOG275246
GeneTree ENSGT00760000118921
HOGENOM HOG000231629
HOVERGEN HBG006263
InParanoid P53412
KO K09374
OMA GQYFRSM
OrthoDB EOG7PP56T
PhylomeDB P53412
TreeFam TF315442
NextBio 20813472
PRO PR:P53412
Proteomes UP000000539
GO GO:0005634
GO:0005667
GO:0001076
GO:0043565
GO:0008270
GO:0048839
GO:0021526
GO:0008045
GO:0043066
GO:0021983
GO:0045944
GO:0021527
GO:0021520
GO:0021521
Gene3D 1.10.10.60
2.10.110.10
InterPro IPR017970
IPR001356
IPR009057
IPR001781
Pfam PF00046
PF00412
SMART SM00389
SM00132
SUPFAM SSF46689
PROSITE PS00027
PS50071
PS00478
PS50023

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

part_of

GO:0005623

cell

PMID:18039974[1]

ECO:0000314

direct assay evidence used in manual assertion

C

  • part_of:(CL:0000100)
  • part_of:(UBERON:0004059)

Seeded From UniProt

complete

involved_in

GO:0045944

positive regulation of transcription by RNA polymerase II

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0267978
MGI:MGI:102673
MGI:MGI:1100513
MGI:MGI:1888519
MGI:MGI:96785
PANTHER:PTN000654232
UniProtKB:Q969G2
UniProtKB:Q9UBR4
WB:WBGene00000438
WB:WBGene00002988
WB:WBGene00003167
WB:WBGene00006654

P

Seeded From UniProt

complete

involved_in

GO:0030182

neuron differentiation

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0002023
FB:FBgn0267978
MGI:MGI:101776
MGI:MGI:102673
MGI:MGI:107792
MGI:MGI:1096343
MGI:MGI:1100513
MGI:MGI:1306803
MGI:MGI:1888519
MGI:MGI:96785
MGI:MGI:99783
PANTHER:PTN000654232
RGD:71076
UniProtKB:P53411
UniProtKB:Q90881
WB:WBGene00000438
WB:WBGene00002988
WB:WBGene00003000
WB:WBGene00003167
WB:WBGene00006654
ZFIN:ZDB-GENE-050114-2
ZFIN:ZDB-GENE-050114-3
ZFIN:ZDB-GENE-050417-210
ZFIN:ZDB-GENE-051220-1
ZFIN:ZDB-GENE-060728-1
ZFIN:ZDB-GENE-980526-131

P

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0267978
MGI:MGI:1096343
MGI:MGI:1100513
MGI:MGI:1306803
MGI:MGI:96785
MGI:MGI:99783
PANTHER:PTN000654232
RGD:71074
UniProtKB:O60663
UniProtKB:O97581
UniProtKB:P53411
UniProtKB:Q9UPM6
WB:WBGene00000438
WB:WBGene00002987
WB:WBGene00002988
WB:WBGene00003167

C

Seeded From UniProt

complete

enables

GO:0000981

DNA-binding transcription factor activity, RNA polymerase II-specific

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1100513
MGI:MGI:1888519
MGI:MGI:96785
PANTHER:PTN000654232
UniProtKB:Q9UBR4

F

Seeded From UniProt

complete

enables

GO:0000977

RNA polymerase II regulatory region sequence-specific DNA binding

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0267978
MGI:MGI:1100513
MGI:MGI:1888519
MGI:MGI:96785
PANTHER:PTN000654232
WB:WBGene00000438
WB:WBGene00002987
WB:WBGene00006654

F

Seeded From UniProt

complete

involved_in

GO:0045944

positive regulation of transcription by RNA polymerase II

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:A2ALD8
ensembl:ENSMUSP00000028302

P

Seeded From UniProt

complete

enables

GO:0001228

DNA-binding transcription activator activity, RNA polymerase II-specific

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:A2ALD8
ensembl:ENSMUSP00000028302

F

Seeded From UniProt

complete

enables

GO:0000978

RNA polymerase II proximal promoter sequence-specific DNA binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:A2ALD8
ensembl:ENSMUSP00000028302

F

Seeded From UniProt

complete

involved_in

GO:0045944

positive regulation of transcription by RNA polymerase II

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P50481
ensembl:ENSMUSP00000028302

P

Seeded From UniProt

complete

involved_in

GO:0045893

positive regulation of transcription, DNA-templated

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P50481
ensembl:ENSMUSP00000028302

P

Seeded From UniProt

complete

involved_in

GO:0043066

negative regulation of apoptotic process

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P50481
ensembl:ENSMUSP00000028302

P

Seeded From UniProt

complete

involved_in

GO:0030154

cell differentiation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P50481
ensembl:ENSMUSP00000028302

P

Seeded From UniProt

complete

involved_in

GO:0021983

pituitary gland development

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P50481
ensembl:ENSMUSP00000028302

P

Seeded From UniProt

complete

involved_in

GO:0021527

spinal cord association neuron differentiation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P50481
ensembl:ENSMUSP00000028302

P

Seeded From UniProt

complete

involved_in

GO:0021526

medial motor column neuron differentiation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P50481
ensembl:ENSMUSP00000028302

P

Seeded From UniProt

complete

involved_in

GO:0021521

ventral spinal cord interneuron specification

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P50481
ensembl:ENSMUSP00000028302

P

Seeded From UniProt

complete

involved_in

GO:0021520

spinal cord motor neuron cell fate specification

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P50481
ensembl:ENSMUSP00000028302

P

Seeded From UniProt

complete

involved_in

GO:0009953

dorsal/ventral pattern formation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P50481
ensembl:ENSMUSP00000028302

P

Seeded From UniProt

complete

involved_in

GO:0008045

motor neuron axon guidance

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P50481
ensembl:ENSMUSP00000028302

P

Seeded From UniProt

complete

part_of

GO:0005667

transcription factor complex

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P50481
ensembl:ENSMUSP00000028302

C

Seeded From UniProt

complete

involved_in

GO:0048839

inner ear development

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9UBR4
ensembl:ENSP00000360811

P

Seeded From UniProt

complete

involved_in

GO:0045944

positive regulation of transcription by RNA polymerase II

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9UBR4
ensembl:ENSP00000360811

P

Seeded From UniProt

complete

enables

GO:0043565

sequence-specific DNA binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9UBR4
ensembl:ENSP00000360811

F

Seeded From UniProt

complete

enables

GO:0001228

DNA-binding transcription activator activity, RNA polymerase II-specific

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9UBR4
ensembl:ENSP00000360811

F

Seeded From UniProt

complete

enables

GO:0001085

RNA polymerase II transcription factor binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9UBR4
ensembl:ENSP00000360811

F

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001356
InterPro:IPR009057

F

Seeded From UniProt

complete

involved_in

GO:0006355

regulation of transcription, DNA-templated

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR017970

P

Seeded From UniProt

complete

enables

GO:0043565

sequence-specific DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR017970

F

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000037
GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0371
UniProtKB-KW:KW-0238

F

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

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Notes

References

See Help:References for how to manage references in GONUTS.

  1. ↑ Moret, F et al. (2007) Semaphorin and neuropilin co-expression in motoneurons sets axon sensitivity to environmental semaphorin sources during motor axon pathfinding. Development 134 4491-501 PubMed GONUTS page
  2. ↑ 2.0 2.1 2.2 2.3 2.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
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