CHICK:IGF1

Species (Taxon ID)	Gallus gallus (Chicken). (9031)
Gene Name(s)	IGF1
Protein Name(s)	Insulin-like growth factor I IGF-I Somatomedin
External Links
UniProt	P18254
EMBL	M32791 M74176
PIR	A41399
RefSeq	NP_001004384.1
UniGene	Gga.850
ProteinModelPortal	P18254
SMR	P18254
STRING	9031.ENSGALP00000020787
PRIDE	P18254
Ensembl	ENSGALT00000020816
GeneID	418090
KEGG	gga:418090
CTD	3479
eggNOG	NOG39886
GeneTree	ENSGT00530000063856
HOGENOM	HOG000233362
HOVERGEN	HBG006137
InParanoid	P18254
KO	K05459
OMA	HTVSYIH
OrthoDB	EOG7TF7CG
PhylomeDB	P18254
TreeFam	TF332820
Reactome	REACT_189769 REACT_189775 REACT_189777 REACT_242665 REACT_247929
NextBio	20821300
PRO	PR:P18254
Proteomes	UP000000539
ExpressionAtlas	P18254
GO	GO:0005615 GO:0001974 GO:0035630 GO:0048754 GO:0001775 GO:0050650 GO:0031017 GO:0097192 GO:0010001 GO:0048839 GO:0048009 GO:0048286 GO:0060463 GO:0060426 GO:0035264 GO:0014896 GO:0045445 GO:0051450 GO:0014904 GO:0060766 GO:0043066 GO:0008285 GO:0070373 GO:2001237 GO:0090201 GO:0034392 GO:0048015 GO:0042104 GO:0070886 GO:0010613 GO:0021940 GO:0043388 GO:0050679 GO:0048146 GO:0046326 GO:0045725 GO:0045821 GO:0043568 GO:0043410 GO:0045840 GO:2000288 GO:0045669 GO:0014068 GO:0033160 GO:0051897 GO:0046579 GO:0014911 GO:0048661 GO:0045944 GO:0042523 GO:0060527 GO:0060736 GO:0060741 GO:0032878 GO:0040014 GO:0014834 GO:0060509 GO:0060510 GO:0030104
Gene3D	1.10.100.10
InterPro	IPR022341 IPR016179 IPR022350 IPR022353 IPR022352
Pfam	PF00049
PRINTS	PR02002 PR02005 PR00276
SMART	SM00078
SUPFAM	SSF56994
PROSITE	PS00262

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
part_of	GO:0005623	cell	PMID:8775065^[1]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(UBERON:0000016)	Seeded From UniProt	complete
involved_in	GO:1990418	response to insulin-like growth factor stimulus	PMID:9568376^[2]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0090277	positive regulation of peptide hormone secretion	PMID:9568376^[2]	ECO:0000314	direct assay evidence used in manual assertion		P	has_regulation_target:(UniProtKB:G8HMZ3)\|has_regulation_target:(UniProtKB:G8HMZ4)\|has_regulation_target:(UniProtKB:F1DFL1)\|has_regulation_target:(UniProtKB:M1T4V2)\|has_regulation_target:(UniProtKB:H6U4T4)\|has_regulation_target:(UniProtKB:G8HMZ1)\|has_regulation_target:(UniProtKB:P18254)\|has_regulation_target:(UniProtKB:C5J073)\|has_regulation_target:(UniProtKB:R4HZM2)	Seeded From UniProt	complete
involved_in	GO:0046676	negative regulation of insulin secretion	PMID:9568376^[2]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0045732	positive regulation of protein catabolic process	PMID:9568376^[2]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0005159	insulin-like growth factor receptor binding	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P05019	F	occurs_in:(CL:0000594)	Seeded From UniProt	complete
involved_in	GO:0090103	cochlea morphogenesis	PMID:14550788^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0061560	cranial ganglion formation	PMID:14550788^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0043524	negative regulation of neuron apoptotic process	PMID:14550788^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	occurs_in:(UBERON:0001648)	Seeded From UniProt	complete
involved_in	GO:0021650	vestibulocochlear nerve formation	PMID:14550788^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0010467	gene expression	PMID:9714146^[4]	ECO:0000314	direct assay evidence used in manual assertion		P	occurs_in:(UBERON:0003051)	Seeded From UniProt	complete
involved_in	GO:0009408	response to heat	PMID:11404306^[5]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0008283	cell population proliferation	PMID:9714146^[4]	ECO:0000314	direct assay evidence used in manual assertion		P	occurs_in:(UBERON:0003051)	Seeded From UniProt	complete
involved_in	GO:0007405	neuroblast proliferation	PMID:14550788^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	occurs_in:(UBERON:0001648)	Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	PMID:11404306^[5]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	PMID:2272467^[6]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	PMID:21325373^[7]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0090201	negative regulation of release of cytochrome c from mitochondria	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P05017	P		Seeded From UniProt	complete
involved_in	GO:0043066	negative regulation of apoptotic process	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P05017	P		Seeded From UniProt	complete
involved_in	GO:0010469	regulation of signaling receptor activity	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0005179	P		Seeded From UniProt	complete
involved_in	GO:0010469	regulation of signaling receptor activity	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0008083	P		Seeded From UniProt	complete
involved_in	GO:0010469	regulation of signaling receptor activity	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0005179	P		Seeded From UniProt	complete
involved_in	GO:0010469	regulation of signaling receptor activity	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0008083	P		Seeded From UniProt	complete
involved_in	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P05019 ensembl:ENSP00000376637	P		Seeded From UniProt	complete
involved_in	GO:2000679	positive regulation of transcription regulatory region DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P05019 ensembl:ENSP00000376637	P		Seeded From UniProt	complete
involved_in	GO:1905460	negative regulation of vascular associated smooth muscle cell apoptotic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P05019 ensembl:ENSP00000376637	P		Seeded From UniProt	complete
involved_in	GO:1904707	positive regulation of vascular smooth muscle cell proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P05019 ensembl:ENSP00000376637	P		Seeded From UniProt	complete
involved_in	GO:1904646	cellular response to amyloid-beta	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P05019 ensembl:ENSP00000376637	P		Seeded From UniProt	complete
involved_in	GO:1904075	positive regulation of trophectodermal cell proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P05019 ensembl:ENSP00000376637	P		Seeded From UniProt	complete
involved_in	GO:1902430	negative regulation of amyloid-beta formation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P05019 ensembl:ENSP00000376637	P		Seeded From UniProt	complete
involved_in	GO:0150079	negative regulation of neuroinflammatory response	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P05019 ensembl:ENSP00000376637	P		Seeded From UniProt	complete
involved_in	GO:0070886	positive regulation of calcineurin-NFAT signaling cascade	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P05019 ensembl:ENSP00000376637	P		Seeded From UniProt	complete
involved_in	GO:0070371	ERK1 and ERK2 cascade	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P05019 ensembl:ENSP00000376637	P		Seeded From UniProt	complete
involved_in	GO:0061051	positive regulation of cell growth involved in cardiac muscle cell development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P05019 ensembl:ENSP00000376637	P		Seeded From UniProt	complete
involved_in	GO:0060283	negative regulation of oocyte development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P05019 ensembl:ENSP00000376637	P		Seeded From UniProt	complete
involved_in	GO:0051450	myoblast proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P05019 ensembl:ENSP00000376637	P		Seeded From UniProt	complete
involved_in	GO:0050821	protein stabilization	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P05019 ensembl:ENSP00000376637	P		Seeded From UniProt	complete
involved_in	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P05019 ensembl:ENSP00000376637	P		Seeded From UniProt	complete
involved_in	GO:0050714	positive regulation of protein secretion	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P05019 ensembl:ENSP00000376637	P		Seeded From UniProt	complete
involved_in	GO:0050679	positive regulation of epithelial cell proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P05019 ensembl:ENSP00000376637	P		Seeded From UniProt	complete
involved_in	GO:0048661	positive regulation of smooth muscle cell proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P05019 ensembl:ENSP00000376637	P		Seeded From UniProt	complete
involved_in	GO:0048146	positive regulation of fibroblast proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P05019 ensembl:ENSP00000376637	P		Seeded From UniProt	complete
involved_in	GO:0048015	phosphatidylinositol-mediated signaling	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P05019 ensembl:ENSP00000376637	P		Seeded From UniProt	complete
involved_in	GO:0048009	insulin-like growth factor receptor signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P05019 ensembl:ENSP00000376637	P		Seeded From UniProt	complete
involved_in	GO:0046579	positive regulation of Ras protein signal transduction	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P05019 ensembl:ENSP00000376637	P		Seeded From UniProt	complete
involved_in	GO:0046326	positive regulation of glucose import	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P05019 ensembl:ENSP00000376637	P		Seeded From UniProt	complete
involved_in	GO:0045944	positive regulation of transcription by RNA polymerase II	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P05019 ensembl:ENSP00000376637	P		Seeded From UniProt	complete
involved_in	GO:0045893	positive regulation of transcription, DNA-templated	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P05019 ensembl:ENSP00000376637	P		Seeded From UniProt	complete
involved_in	GO:0045840	positive regulation of mitotic nuclear division	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P05019 ensembl:ENSP00000376637	P		Seeded From UniProt	complete
involved_in	GO:0045821	positive regulation of glycolytic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P05019 ensembl:ENSP00000376637	P		Seeded From UniProt	complete
involved_in	GO:0045725	positive regulation of glycogen biosynthetic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P05019 ensembl:ENSP00000376637	P		Seeded From UniProt	complete
involved_in	GO:0045669	positive regulation of osteoblast differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P05019 ensembl:ENSP00000376637	P		Seeded From UniProt	complete
involved_in	GO:0045445	myoblast differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P05019 ensembl:ENSP00000376637	P		Seeded From UniProt	complete
involved_in	GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P05019 ensembl:ENSP00000376637	P		Seeded From UniProt	complete
involved_in	GO:0043491	protein kinase B signaling	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P05019 ensembl:ENSP00000376637	P		Seeded From UniProt	complete
involved_in	GO:0043410	positive regulation of MAPK cascade	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P05019 ensembl:ENSP00000376637	P		Seeded From UniProt	complete
involved_in	GO:0043388	positive regulation of DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P05019 ensembl:ENSP00000376637	P		Seeded From UniProt	complete
involved_in	GO:0043066	negative regulation of apoptotic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P05019 ensembl:ENSP00000376637	P		Seeded From UniProt	complete
part_of	GO:0042567	insulin-like growth factor ternary complex	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P05019 ensembl:ENSP00000376637	C		Seeded From UniProt	complete
involved_in	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P05019 ensembl:ENSP00000376637	P		Seeded From UniProt	complete
involved_in	GO:0042104	positive regulation of activated T cell proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P05019 ensembl:ENSP00000376637	P		Seeded From UniProt	complete
involved_in	GO:0040014	regulation of multicellular organism growth	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P05019 ensembl:ENSP00000376637	P		Seeded From UniProt	complete
part_of	GO:0035867	alphav-beta3 integrin-IGF-1-IGF1R complex	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P05019 ensembl:ENSP00000376637	C		Seeded From UniProt	complete
involved_in	GO:0035630	bone mineralization involved in bone maturation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P05019 ensembl:ENSP00000376637	P		Seeded From UniProt	complete
involved_in	GO:0034392	negative regulation of smooth muscle cell apoptotic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P05019 ensembl:ENSP00000376637	P		Seeded From UniProt	complete
involved_in	GO:0032720	negative regulation of tumor necrosis factor production	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P05019 ensembl:ENSP00000376637	P		Seeded From UniProt	complete
involved_in	GO:0032691	negative regulation of interleukin-1 beta production	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P05019 ensembl:ENSP00000376637	P		Seeded From UniProt	complete
involved_in	GO:0032148	activation of protein kinase B activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P05019 ensembl:ENSP00000376637	P		Seeded From UniProt	complete
involved_in	GO:0030335	positive regulation of cell migration	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P05019 ensembl:ENSP00000376637	P		Seeded From UniProt	complete
involved_in	GO:0030166	proteoglycan biosynthetic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P05019 ensembl:ENSP00000376637	P		Seeded From UniProt	complete
involved_in	GO:0014911	positive regulation of smooth muscle cell migration	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P05019 ensembl:ENSP00000376637	P		Seeded From UniProt	complete
involved_in	GO:0014904	myotube cell development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P05019 ensembl:ENSP00000376637	P		Seeded From UniProt	complete
involved_in	GO:0014896	muscle hypertrophy	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P05019 ensembl:ENSP00000376637	P		Seeded From UniProt	complete
involved_in	GO:0014834	skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P05019 ensembl:ENSP00000376637	P		Seeded From UniProt	complete
involved_in	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P05019 ensembl:ENSP00000376637	P		Seeded From UniProt	complete
involved_in	GO:0014065	phosphatidylinositol 3-kinase signaling	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P05019 ensembl:ENSP00000376637	P		Seeded From UniProt	complete
involved_in	GO:0010629	negative regulation of gene expression	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P05019 ensembl:ENSP00000376637	P		Seeded From UniProt	complete
involved_in	GO:0010628	positive regulation of gene expression	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P05019 ensembl:ENSP00000376637	P		Seeded From UniProt	complete
involved_in	GO:0010613	positive regulation of cardiac muscle hypertrophy	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P05019 ensembl:ENSP00000376637	P		Seeded From UniProt	complete
involved_in	GO:0010560	positive regulation of glycoprotein biosynthetic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P05019 ensembl:ENSP00000376637	P		Seeded From UniProt	complete
involved_in	GO:0010468	regulation of gene expression	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P05019 ensembl:ENSP00000376637	P		Seeded From UniProt	complete
involved_in	GO:0009408	response to heat	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P05019 ensembl:ENSP00000376637	P		Seeded From UniProt	complete
involved_in	GO:0008284	positive regulation of cell population proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P05019 ensembl:ENSP00000376637	P		Seeded From UniProt	complete
involved_in	GO:0008283	cell population proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P05019 ensembl:ENSP00000376637	P		Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P05019 ensembl:ENSP00000376637	C		Seeded From UniProt	complete
enables	GO:0005179	hormone activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P05019 ensembl:ENSP00000376637	F		Seeded From UniProt	complete
enables	GO:0005178	integrin binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P05019 ensembl:ENSP00000376637	F		Seeded From UniProt	complete
enables	GO:0005159	insulin-like growth factor receptor binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P05019 ensembl:ENSP00000376637	F		Seeded From UniProt	complete
enables	GO:0005158	insulin receptor binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P05019 ensembl:ENSP00000376637	F		Seeded From UniProt	complete
involved_in	GO:0001775	cell activation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P05019 ensembl:ENSP00000376637	P		Seeded From UniProt	complete
involved_in	GO:0000187	activation of MAPK activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P05019 ensembl:ENSP00000376637	P		Seeded From UniProt	complete
enables	GO:0005179	hormone activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR016179 InterPro:IPR022350 InterPro:IPR022352	F		Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR016179	C		Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR022341 InterPro:IPR022350	C		Seeded From UniProt	complete
enables	GO:0008083	growth factor activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR022341 InterPro:IPR022350	F		Seeded From UniProt	complete
enables	GO:0008083	growth factor activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0339	F		Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0964 UniProtKB-SubCell:SL-0243	C		Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ Reinecke, M et al. (1995) Immunohistochemical localization of insulin-like growth factor I and II in the endocrine pancreas of birds, reptiles, and amphibia. Gen. Comp. Endocrinol. 100 385-96 PubMed GONUTS page
↑ ^2.0 ^2.1 ^2.2 ^2.3 Czerwinski, SM et al. (1998) The effect of insulin-like growth factor-I (IGF-I) on protein turnover in the meat-type chicken (Gallus domesticus). Comp. Biochem. Physiol. C, Pharmacol. Toxicol. Endocrinol. 119 75-80 PubMed GONUTS page
↑ ^3.0 ^3.1 ^3.2 ^3.3 ^3.4 Camarero, G et al. (2003) Insulin-like growth factor 1 is required for survival of transit-amplifying neuroblasts and differentiation of otic neurons. Dev. Biol. 262 242-53 PubMed GONUTS page
↑ ^4.0 ^4.1 León, Y et al. (1998) Induction of cell growth by insulin and insulin-like growth factor-I is associated with Jun expression in the otic vesicle. J. Comp. Neurol. 398 323-32 PubMed GONUTS page
↑ ^5.0 ^5.1 Halevy, O et al. (2001) Early-age heat exposure affects skeletal muscle satellite cell proliferation and differentiation in chicks. Am. J. Physiol. Regul. Integr. Comp. Physiol. 281 R302-9 PubMed GONUTS page
↑ Ballard, FJ et al. (1990) Chicken insulin-like growth factor-I: amino acid sequence, radioimmunoassay, and plasma levels between strains and during growth. Gen. Comp. Endocrinol. 79 459-68 PubMed GONUTS page
↑ Song, ZG et al. (2011) Dexamethasone alters the expression of genes related to the growth of skeletal muscle in chickens (Gallus gallus domesticus). J. Mol. Endocrinol. 46 217-25 PubMed GONUTS page

[PMID:8775065-1] Reinecke, M et al. (1995) Immunohistochemical localization of insulin-like growth factor I and II in the endocrine pancreas of birds, reptiles, and amphibia. Gen. Comp. Endocrinol. 100 385-96 PubMed GONUTS page

[PMID:9568376-2] 2.0 ^2.1 ^2.2 ^2.3 Czerwinski, SM et al. (1998) The effect of insulin-like growth factor-I (IGF-I) on protein turnover in the meat-type chicken (Gallus domesticus). Comp. Biochem. Physiol. C, Pharmacol. Toxicol. Endocrinol. 119 75-80 PubMed GONUTS page

[PMID:14550788-3] 3.0 ^3.1 ^3.2 ^3.3 ^3.4 Camarero, G et al. (2003) Insulin-like growth factor 1 is required for survival of transit-amplifying neuroblasts and differentiation of otic neurons. Dev. Biol. 262 242-53 PubMed GONUTS page

[PMID:9714146-4] 4.0 ^4.1 León, Y et al. (1998) Induction of cell growth by insulin and insulin-like growth factor-I is associated with Jun expression in the otic vesicle. J. Comp. Neurol. 398 323-32 PubMed GONUTS page

[PMID:11404306-5] 5.0 ^5.1 Halevy, O et al. (2001) Early-age heat exposure affects skeletal muscle satellite cell proliferation and differentiation in chicks. Am. J. Physiol. Regul. Integr. Comp. Physiol. 281 R302-9 PubMed GONUTS page

[PMID:2272467-6] Ballard, FJ et al. (1990) Chicken insulin-like growth factor-I: amino acid sequence, radioimmunoassay, and plasma levels between strains and during growth. Gen. Comp. Endocrinol. 79 459-68 PubMed GONUTS page

[PMID:21325373-7] Song, ZG et al. (2011) Dexamethasone alters the expression of genes related to the growth of skeletal muscle in chickens (Gallus gallus domesticus). J. Mol. Endocrinol. 46 217-25 PubMed GONUTS page

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CHICK:IGF1

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