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CHICK:HMGB3

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) HMGB3 (synonyms: HMG2A, HMG4)
Protein Name(s) High mobility group protein B3

High mobility group protein 2a HMG-2a High mobility group protein 4 HMG-4

External Links
UniProt P40618
EMBL X63463
AADN03004033
AADN03004127
D14314
PIR S22359
RefSeq NP_990626.2
UniGene Gga.4513
PRIDE P40618
GeneID 396232
KEGG gga:396232
CTD 3149
HOVERGEN HBG009000
InParanoid P40618
KO K11296
OrthoDB EOG7WHHBQ
TreeFam TF105371
NextBio 20816284
PRO PR:P40618
Proteomes UP000000539
GO GO:0005694
GO:0005634
GO:0008301
GO:0000400
GO:0044822
GO:0032392
GO:0045578
GO:0045638
Gene3D 1.10.30.10
InterPro IPR009071
IPR017967
IPR031077
PANTHER PTHR13711:SF144
Pfam PF00505
PF09011
SMART SM00398
SUPFAM SSF47095
PROSITE PS00353
PS50118

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

enables

GO:0000400

four-way junction DNA binding

PMID:11080451[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0008301

DNA binding, bending

PMID:11080451[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0032392

DNA geometric change

PMID:11080451[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0045944

positive regulation of transcription by RNA polymerase II

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:96113
MGI:MGI:96157
PANTHER:PTN001009623
UniProtKB:P09429
UniProtKB:P26583
WB:WBGene00001972

P

Seeded From UniProt

complete

involved_in

GO:0045089

positive regulation of innate immune response

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:96113
MGI:MGI:96157
PANTHER:PTN001009623
UniProtKB:P09429
UniProtKB:P10103
UniProtKB:P12682

P

Seeded From UniProt

complete

enables

GO:0008301

DNA binding, bending

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0004362
FB:FBgn0278608
PANTHER:PTN000345179
RGD:2802
SGD:S000002157
SGD:S000004676
SGD:S000006256
UniProtKB:F1RJ01
UniProtKB:F2Z594
UniProtKB:P09429
UniProtKB:P10103
UniProtKB:P12682
UniProtKB:P17741
UniProtKB:P26583
UniProtKB:P26584
UniProtKB:P40618
UniProtKB:P40673
UniProtKB:Q32L31
UniProtKB:Q8I616
UniProtKB:Q8IB14
UniProtKB:Q9YH06

F

Seeded From UniProt

complete

enables

GO:0008134

transcription factor binding

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0278608
MGI:MGI:96157
PANTHER:PTN000345179
RGD:2802
UniProtKB:P09429

F

Seeded From UniProt

complete

involved_in

GO:0006357

regulation of transcription by RNA polymerase II

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0278608
MGI:MGI:96113
MGI:MGI:96157
PANTHER:PTN000346026
UniProtKB:P09429
UniProtKB:P26583
WB:WBGene00001972

P

Seeded From UniProt

complete

involved_in

GO:0006338

chromatin remodeling

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000345179
SGD:S000002157
SGD:S000006256

P

Seeded From UniProt

complete

involved_in

GO:0006310

DNA recombination

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001009623
UniProtKB:P09429
UniProtKB:P10103
UniProtKB:P40673
UniProtKB:Q32L31

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:96113
MGI:MGI:96157
PANTHER:PTN001009623
RGD:2802
UniProtKB:P26583

C

Seeded From UniProt

complete

part_of

GO:0000790

nuclear chromatin

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:96157
PANTHER:PTN000346026
SGD:S000002160
UniProtKB:F1RJ01
UniProtKB:F2Z594
UniProtKB:P12682
UniProtKB:P17741

C

Seeded From UniProt

complete

involved_in

GO:0045638

negative regulation of myeloid cell differentiation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:O54879
ensembl:ENSMUSP00000110229

P

Seeded From UniProt

complete

involved_in

GO:0045578

negative regulation of B cell differentiation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:O54879
ensembl:ENSMUSP00000110229

P

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:O54879
ensembl:ENSMUSP00000110229

C

Seeded From UniProt

complete

enables

GO:0003723

RNA binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:O54879
ensembl:ENSMUSP00000110229

F

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:O54879
ensembl:ENSMUSP00000110229

F

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR017967

F

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR017967

C

Seeded From UniProt

complete

involved_in

GO:0002376

immune system process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0391

P

Seeded From UniProt

complete

involved_in

GO:0045087

innate immune response

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0399

P

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0238

F

Seeded From UniProt

complete

part_of

GO:0005694

chromosome

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0158
UniProtKB-SubCell:SL-0468

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 Lee, KB & Thomas, JO (2000) The effect of the acidic tail on the DNA-binding properties of the HMG1,2 class of proteins: insights from tail switching and tail removal. J. Mol. Biol. 304 135-49 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 2.8 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page