CHICK:HMGB3

Species (Taxon ID)	Gallus gallus (Chicken). (9031)
Gene Name(s)	HMGB3 (synonyms: HMG2A, HMG4)
Protein Name(s)	High mobility group protein B3 High mobility group protein 2a HMG-2a High mobility group protein 4 HMG-4
External Links
UniProt	P40618
EMBL	X63463 AADN03004033 AADN03004127 D14314
PIR	S22359
RefSeq	NP_990626.2
UniGene	Gga.4513
PRIDE	P40618
GeneID	396232
KEGG	gga:396232
CTD	3149
HOVERGEN	HBG009000
InParanoid	P40618
KO	K11296
OrthoDB	EOG7WHHBQ
TreeFam	TF105371
NextBio	20816284
PRO	PR:P40618
Proteomes	UP000000539
GO	GO:0005694 GO:0005634 GO:0008301 GO:0000400 GO:0044822 GO:0032392 GO:0045578 GO:0045638
Gene3D	1.10.30.10
InterPro	IPR009071 IPR017967 IPR031077
PANTHER	PTHR13711:SF144
Pfam	PF00505 PF09011
SMART	SM00398
SUPFAM	SSF47095
PROSITE	PS00353 PS50118

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
enables	GO:0000400	four-way junction DNA binding	PMID:11080451^[1]	ECO:0000314	direct assay evidence used in manual assertion		F	Seeded From UniProt	complete
enables	GO:0008301	DNA binding, bending	PMID:11080451^[1]	ECO:0000314	direct assay evidence used in manual assertion		F	Seeded From UniProt	complete
involved_in	GO:0032392	DNA geometric change	PMID:11080451^[1]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0045944	positive regulation of transcription by RNA polymerase II	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:96113 MGI:MGI:96157 PANTHER:PTN001009623 UniProtKB:P09429 UniProtKB:P26583 WB:WBGene00001972	P	Seeded From UniProt	complete
involved_in	GO:0045089	positive regulation of innate immune response	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:96113 MGI:MGI:96157 PANTHER:PTN001009623 UniProtKB:P09429 UniProtKB:P10103 UniProtKB:P12682	P	Seeded From UniProt	complete
enables	GO:0008301	DNA binding, bending	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0004362 FB:FBgn0278608 PANTHER:PTN000345179 RGD:2802 SGD:S000002157 SGD:S000004676 SGD:S000006256 UniProtKB:F1RJ01 UniProtKB:F2Z594 UniProtKB:P09429 UniProtKB:P10103 UniProtKB:P12682 UniProtKB:P17741 UniProtKB:P26583 UniProtKB:P26584 UniProtKB:P40618 UniProtKB:P40673 UniProtKB:Q32L31 UniProtKB:Q8I616 UniProtKB:Q8IB14 UniProtKB:Q9YH06	F	Seeded From UniProt	complete
enables	GO:0008134	transcription factor binding	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0278608 MGI:MGI:96157 PANTHER:PTN000345179 RGD:2802 UniProtKB:P09429	F	Seeded From UniProt	complete
involved_in	GO:0006357	regulation of transcription by RNA polymerase II	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0278608 MGI:MGI:96113 MGI:MGI:96157 PANTHER:PTN000346026 UniProtKB:P09429 UniProtKB:P26583 WB:WBGene00001972	P	Seeded From UniProt	complete
involved_in	GO:0006338	chromatin remodeling	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000345179 SGD:S000002157 SGD:S000006256	P	Seeded From UniProt	complete
involved_in	GO:0006310	DNA recombination	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN001009623 UniProtKB:P09429 UniProtKB:P10103 UniProtKB:P40673 UniProtKB:Q32L31	P	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:96113 MGI:MGI:96157 PANTHER:PTN001009623 RGD:2802 UniProtKB:P26583	C	Seeded From UniProt	complete
part_of	GO:0000790	nuclear chromatin	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:96157 PANTHER:PTN000346026 SGD:S000002160 UniProtKB:F1RJ01 UniProtKB:F2Z594 UniProtKB:P12682 UniProtKB:P17741	C	Seeded From UniProt	complete
involved_in	GO:0045638	negative regulation of myeloid cell differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O54879 ensembl:ENSMUSP00000110229	P	Seeded From UniProt	complete
involved_in	GO:0045578	negative regulation of B cell differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O54879 ensembl:ENSMUSP00000110229	P	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O54879 ensembl:ENSMUSP00000110229	C	Seeded From UniProt	complete
enables	GO:0003723	RNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O54879 ensembl:ENSMUSP00000110229	F	Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O54879 ensembl:ENSMUSP00000110229	F	Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR017967	F	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR017967	C	Seeded From UniProt	complete
involved_in	GO:0002376	immune system process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0391	P	Seeded From UniProt	complete
involved_in	GO:0045087	innate immune response	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0399	P	Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0238	F	Seeded From UniProt	complete
part_of	GO:0005694	chromosome	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0158 UniProtKB-SubCell:SL-0468	C	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0963 UniProtKB-SubCell:SL-0086	C	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0539 UniProtKB-SubCell:SL-0191	C	Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 Lee, KB & Thomas, JO (2000) The effect of the acidic tail on the DNA-binding properties of the HMG1,2 class of proteins: insights from tail switching and tail removal. J. Mol. Biol. 304 135-49 PubMed GONUTS page
↑ ^2.0 ^2.1 ^2.2 ^2.3 ^2.4 ^2.5 ^2.6 ^2.7 ^2.8 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:11080451-1] 1.0 ^1.1 ^1.2 Lee, KB & Thomas, JO (2000) The effect of the acidic tail on the DNA-binding properties of the HMG1,2 class of proteins: insights from tail switching and tail removal. J. Mol. Biol. 304 135-49 PubMed GONUTS page

[PMID:21873635-2] 2.0 ^2.1 ^2.2 ^2.3 ^2.4 ^2.5 ^2.6 ^2.7 ^2.8 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

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CHICK:HMGB3

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