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CHICK:HMGB2

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) HMGB2 (synonyms: HMG2)
Protein Name(s) High mobility group protein B2

High mobility group protein 2 HMG-2

External Links
UniProt P26584
EMBL M83235
M80574
PIR JC1114
JC1129
RefSeq NP_990817.1
UniGene Gga.4061
ProteinModelPortal P26584
SMR P26584
BioGrid 676729
STRING 9031.ENSGALP00000017462
PaxDb P26584
PRIDE P26584
GeneID 396482
KEGG gga:396482
CTD 3148
eggNOG NOG320947
HOGENOM HOG000197861
HOVERGEN HBG009000
InParanoid P26584
KO K11295
PhylomeDB P26584
NextBio 20816521
PRO PR:P26584
Proteomes UP000000539
GO GO:0000793
GO:0005737
GO:0005615
GO:0005634
GO:0048471
GO:0008301
GO:0008144
GO:0000400
GO:0050829
GO:0050830
GO:0032392
GO:0002437
GO:0006357
GO:0042493
GO:0032496
Gene3D 1.10.30.10
InterPro IPR009071
IPR017967
IPR031075
PANTHER PTHR13711:SF181
Pfam PF00505
PF09011
SMART SM00398
SUPFAM SSF47095
PROSITE PS00353
PS50118

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0050830

defense response to Gram-positive bacterium

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P26583

P

Seeded From UniProt

complete

involved_in

GO:0050830

defense response to Gram-positive bacterium

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q5U071

P

Seeded From UniProt

complete

involved_in

GO:0050829

defense response to Gram-negative bacterium

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q5U071

P

Seeded From UniProt

complete

involved_in

GO:0050829

defense response to Gram-negative bacterium

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P26583

P

Seeded From UniProt

complete

involved_in

GO:0050829

defense response to Gram-negative bacterium

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:X2JGB1

P

  • occurs_in:(CL:0000738)
  • occurs_in:(UBERON:0002106)
  • occurs_in:(UBERON:0002113)

Seeded From UniProt

complete

involved_in

GO:0050829

defense response to Gram-negative bacterium

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:X2JGB1

P

  • occurs_in:(UBERON:0002106)
  • occurs_in:(UBERON:0002113)

Seeded From UniProt

complete

enables

GO:0000400

four-way junction DNA binding

PMID:11080451[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0008301

DNA binding, bending

PMID:11080451[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0032392

DNA geometric change

PMID:11080451[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P30681

C

Seeded From UniProt

complete

enables

GO:0008144

drug binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q3U566

F

Seeded From UniProt

complete

involved_in

GO:0042493

response to drug

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q3U566

P

Seeded From UniProt

complete

involved_in

GO:0032496

response to lipopolysaccharide

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q3U566

P

Seeded From UniProt

complete

involved_in

GO:0002437

inflammatory response to antigenic stimulus

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q3U566

P

Seeded From UniProt

complete

involved_in

GO:0032496

response to lipopolysaccharide

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P30681

P

Seeded From UniProt

complete

involved_in

GO:0002437

inflammatory response to antigenic stimulus

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P30681

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q3U566

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q3U566

C

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q3U566

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P30681

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P30681

C

Seeded From UniProt

complete

part_of

GO:0048471

perinuclear region of cytoplasm

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P26583

C

Seeded From UniProt

complete

enables

GO:0008301

DNA binding, bending

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P26583

F

Seeded From UniProt

complete

involved_in

GO:0006357

regulation of transcription by RNA polymerase II

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P26583

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P26583

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P26583

C

Seeded From UniProt

complete

part_of

GO:0000793

condensed chromosome

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P26583

C

Seeded From UniProt

complete

involved_in

GO:0045944

positive regulation of transcription by RNA polymerase II

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:96113
MGI:MGI:96157
PANTHER:PTN001009623
UniProtKB:P09429
UniProtKB:P26583
WB:WBGene00001972

P

Seeded From UniProt

complete

involved_in

GO:0045089

positive regulation of innate immune response

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:96113
MGI:MGI:96157
PANTHER:PTN001009623
UniProtKB:P09429
UniProtKB:P10103
UniProtKB:P12682

P

Seeded From UniProt

complete

enables

GO:0008301

DNA binding, bending

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0004362
FB:FBgn0278608
PANTHER:PTN000345179
RGD:2802
SGD:S000002157
SGD:S000004676
SGD:S000006256
UniProtKB:F1RJ01
UniProtKB:F2Z594
UniProtKB:P09429
UniProtKB:P10103
UniProtKB:P12682
UniProtKB:P17741
UniProtKB:P26583
UniProtKB:P26584
UniProtKB:P40618
UniProtKB:P40673
UniProtKB:Q32L31
UniProtKB:Q8I616
UniProtKB:Q8IB14
UniProtKB:Q9YH06

F

Seeded From UniProt

complete

enables

GO:0008134

transcription factor binding

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0278608
MGI:MGI:96157
PANTHER:PTN000345179
RGD:2802
UniProtKB:P09429

F

Seeded From UniProt

complete

involved_in

GO:0006357

regulation of transcription by RNA polymerase II

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0278608
MGI:MGI:96113
MGI:MGI:96157
PANTHER:PTN000346026
UniProtKB:P09429
UniProtKB:P26583
WB:WBGene00001972

P

Seeded From UniProt

complete

involved_in

GO:0006338

chromatin remodeling

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000345179
SGD:S000002157
SGD:S000006256

P

Seeded From UniProt

complete

involved_in

GO:0006310

DNA recombination

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001009623
UniProtKB:P09429
UniProtKB:P10103
UniProtKB:P40673
UniProtKB:Q32L31

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:96113
MGI:MGI:96157
PANTHER:PTN001009623
RGD:2802
UniProtKB:P26583

C

Seeded From UniProt

complete

part_of

GO:0000790

nuclear chromatin

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:96157
PANTHER:PTN000346026
SGD:S000002160
UniProtKB:F1RJ01
UniProtKB:F2Z594
UniProtKB:P12682
UniProtKB:P17741

C

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR017967

F

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR017967

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0238

F

Seeded From UniProt

complete

involved_in

GO:0006954

inflammatory response

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0395

P

Seeded From UniProt

complete

part_of

GO:0005694

chromosome

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0158
UniProtKB-SubCell:SL-0468

C

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0964
UniProtKB-SubCell:SL-0243

C

Seeded From UniProt

complete

involved_in

GO:0006310

DNA recombination

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0233

P

Seeded From UniProt

complete

involved_in

GO:0045087

innate immune response

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0399

P

Seeded From UniProt

complete

involved_in

GO:0002376

immune system process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0391

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 Lee, KB & Thomas, JO (2000) The effect of the acidic tail on the DNA-binding properties of the HMG1,2 class of proteins: insights from tail switching and tail removal. J. Mol. Biol. 304 135-49 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 2.8 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page