CHICK:DLX5

Species (Taxon ID)	Gallus gallus (Chicken). (9031)
Gene Name(s)	DLX5 (synonyms: DLX-5)
Protein Name(s)	Homeobox protein DLX-5 cDlx
External Links
UniProt	P50577
EMBL	U25274 AF096161
RefSeq	NP_989490.1
UniGene	Gga.919
ProteinModelPortal	P50577
SMR	P50577
STRING	9031.ENSGALP00000015233
Ensembl	ENSGALT00000014862
GeneID	373969
KEGG	gga:373969
CTD	1749
eggNOG	NOG263092
GeneTree	ENSGT00800000124040
HOGENOM	HOG000231940
HOVERGEN	HBG005493
InParanoid	P50577
KO	K18489
OMA	QSPAVWD
PhylomeDB	P50577
TreeFam	TF350606
NextBio	20813498
PRO	PR:P50577
Proteomes	UP000000539
GO	GO:0005737 GO:0000790 GO:0000978 GO:0001077 GO:0048646 GO:0007411 GO:0030509 GO:0008283 GO:0071773 GO:0030326 GO:0001958 GO:0030855 GO:0060325 GO:0042472 GO:0060166 GO:0001649 GO:0060021 GO:0090263 GO:0050679 GO:1901522
Gene3D	1.10.10.60
InterPro	IPR022135 IPR017970 IPR001356 IPR020479 IPR009057 IPR000047
Pfam	PF12413 PF00046
PRINTS	PR00024 PR00031
SMART	SM00389
SUPFAM	SSF46689
PROSITE	PS00027 PS50071

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
involved_in	GO:0048646	anatomical structure formation involved in morphogenesis	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:101926 PANTHER:PTN002802880 ZFIN:ZDB-GENE-990415-49	P	Seeded From UniProt	complete
involved_in	GO:0045944	positive regulation of transcription by RNA polymerase II	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:101926 MGI:MGI:94901 MGI:MGI:94902 PANTHER:PTN000675745 UniProtKB:P56177	P	Seeded From UniProt	complete
enables	GO:0043565	sequence-specific DNA binding	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:101926 MGI:MGI:1919200 MGI:MGI:2669849 MGI:MGI:94901 MGI:MGI:94902 PANTHER:PTN002802863 UniProtKB:O95231 UniProtKB:Q92988 UniProtKB:Q9H9S0 ZFIN:ZDB-GENE-030131-5486 ZFIN:ZDB-GENE-980526-280	F	Seeded From UniProt	complete
involved_in	GO:0030154	cell differentiation	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:101926 MGI:MGI:101927 MGI:MGI:94901 MGI:MGI:94902 PANTHER:PTN000675745 ZFIN:ZDB-GENE-980526-212	P	Seeded From UniProt	complete
involved_in	GO:0006357	regulation of transcription by RNA polymerase II	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:101926 MGI:MGI:1919200 MGI:MGI:2669849 MGI:MGI:94901 MGI:MGI:94902 PANTHER:PTN002802863 RGD:1303178 UniProtKB:O95231 UniProtKB:P56177 UniProtKB:Q92988 UniProtKB:Q9H9S0 WB:WBGene00000446 Xenbase:XB-GENE-920868	P	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0000157 FB:FBgn0000529 MGI:MGI:101926 MGI:MGI:1919200 MGI:MGI:2669849 MGI:MGI:94901 MGI:MGI:94902 MGI:MGI:94903 PANTHER:PTN002802863 RGD:1303178 UniProtKB:A7Y7W3 UniProtKB:P56177 UniProtKB:Q6NSW7 UniProtKB:Q9H9S0 WB:WBGene00000446 WB:WBGene00013583	C	Seeded From UniProt	complete
enables	GO:0003700	DNA-binding transcription factor activity	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1919200 MGI:MGI:2669849 MGI:MGI:94902 PANTHER:PTN002802863 UniProtKB:Q9H9S0	F	Seeded From UniProt	complete
enables	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:101926 MGI:MGI:2669849 PANTHER:PTN002802863 UniProtKB:Q92988	F	Seeded From UniProt	complete
involved_in	GO:0045893	positive regulation of transcription, DNA-templated	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P56178 ensembl:ENSP00000222598	P	Seeded From UniProt	complete
enables	GO:0044212	transcription regulatory region DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P56178 ensembl:ENSP00000222598	F	Seeded From UniProt	complete
involved_in	GO:0008283	cell population proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P56178 ensembl:ENSP00000222598	P	Seeded From UniProt	complete
involved_in	GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70396 ensembl:ENSMUSP00000052559	P	Seeded From UniProt	complete
involved_in	GO:0097376	interneuron axon guidance	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70396 ensembl:ENSMUSP00000052559	P	Seeded From UniProt	complete
involved_in	GO:0090263	positive regulation of canonical Wnt signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70396 ensembl:ENSMUSP00000052559	P	Seeded From UniProt	complete
enables	GO:0071837	HMG box domain binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70396 ensembl:ENSMUSP00000052559	F	Seeded From UniProt	complete
involved_in	GO:0071773	cellular response to BMP stimulus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70396 ensembl:ENSMUSP00000052559	P	Seeded From UniProt	complete
involved_in	GO:0060349	bone morphogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70396 ensembl:ENSMUSP00000052559	P	Seeded From UniProt	complete
involved_in	GO:0060325	face morphogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70396 ensembl:ENSMUSP00000052559	P	Seeded From UniProt	complete
involved_in	GO:0060322	head development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70396 ensembl:ENSMUSP00000052559	P	Seeded From UniProt	complete
involved_in	GO:0060166	olfactory pit development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70396 ensembl:ENSMUSP00000052559	P	Seeded From UniProt	complete
involved_in	GO:0060021	roof of mouth development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70396 ensembl:ENSMUSP00000052559	P	Seeded From UniProt	complete
involved_in	GO:0050679	positive regulation of epithelial cell proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70396 ensembl:ENSMUSP00000052559	P	Seeded From UniProt	complete
involved_in	GO:0048646	anatomical structure formation involved in morphogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70396 ensembl:ENSMUSP00000052559	P	Seeded From UniProt	complete
involved_in	GO:0045944	positive regulation of transcription by RNA polymerase II	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70396 ensembl:ENSMUSP00000052559	P	Seeded From UniProt	complete
involved_in	GO:0045893	positive regulation of transcription, DNA-templated	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70396 ensembl:ENSMUSP00000052559	P	Seeded From UniProt	complete
enables	GO:0044212	transcription regulatory region DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70396 ensembl:ENSMUSP00000052559	F	Seeded From UniProt	complete
involved_in	GO:0043583	ear development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70396 ensembl:ENSMUSP00000052559	P	Seeded From UniProt	complete
involved_in	GO:0042472	inner ear morphogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70396 ensembl:ENSMUSP00000052559	P	Seeded From UniProt	complete
involved_in	GO:0030855	epithelial cell differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70396 ensembl:ENSMUSP00000052559	P	Seeded From UniProt	complete
involved_in	GO:0030509	BMP signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70396 ensembl:ENSMUSP00000052559	P	Seeded From UniProt	complete
involved_in	GO:0030326	embryonic limb morphogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70396 ensembl:ENSMUSP00000052559	P	Seeded From UniProt	complete
involved_in	GO:0021889	olfactory bulb interneuron differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70396 ensembl:ENSMUSP00000052559	P	Seeded From UniProt	complete
involved_in	GO:0010628	positive regulation of gene expression	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70396 ensembl:ENSMUSP00000052559	P	Seeded From UniProt	complete
involved_in	GO:0007411	axon guidance	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70396 ensembl:ENSMUSP00000052559	P	Seeded From UniProt	complete
involved_in	GO:0007409	axonogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70396 ensembl:ENSMUSP00000052559	P	Seeded From UniProt	complete
involved_in	GO:0006355	regulation of transcription, DNA-templated	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70396 ensembl:ENSMUSP00000052559	P	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70396 ensembl:ENSMUSP00000052559	C	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70396 ensembl:ENSMUSP00000052559	C	Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70396 ensembl:ENSMUSP00000052559	F	Seeded From UniProt	complete
involved_in	GO:0001958	endochondral ossification	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70396 ensembl:ENSMUSP00000052559	P	Seeded From UniProt	complete
involved_in	GO:0001649	osteoblast differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70396 ensembl:ENSMUSP00000052559	P	Seeded From UniProt	complete
enables	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70396 ensembl:ENSMUSP00000052559	F	Seeded From UniProt	complete
enables	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70396 ensembl:ENSMUSP00000052559	F	Seeded From UniProt	complete
part_of	GO:0000790	nuclear chromatin	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70396 ensembl:ENSMUSP00000052559	C	Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000047 InterPro:IPR001356 InterPro:IPR009057 InterPro:IPR020479	F	Seeded From UniProt	complete
involved_in	GO:0006355	regulation of transcription, DNA-templated	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR017970	P	Seeded From UniProt	complete
enables	GO:0043565	sequence-specific DNA binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR017970	F	Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000037 GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0238 UniProtKB-KW:KW-0371	F	Seeded From UniProt	complete
involved_in	GO:0001503	ossification	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0892	P	Seeded From UniProt	complete
involved_in	GO:0007275	multicellular organism development	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0217	P	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0539 UniProtKB-SubCell:SL-0191	C	Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 ^1.6 ^1.7 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:21873635-1] 1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 ^1.6 ^1.7 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

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CHICK:DLX5

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