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CHICK:CHP1

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) CHP1 (synonyms: CHP)
Protein Name(s) Calcineurin B homologous protein 1

Calcineurin B-like protein Calcium-binding protein CHP Calcium-binding protein p22 EF-hand calcium-binding domain-containing protein p22

External Links
UniProt Q5ZM44
EMBL AJ719540
RefSeq NP_001007931.1
UniGene Gga.16756
ProteinModelPortal Q5ZM44
SMR Q5ZM44
BioGrid 683765
IntAct Q5ZM44
STRING 9031.ENSGALP00000032005
PaxDb Q5ZM44
Ensembl ENSGALT00000032642
GeneID 423211
KEGG gga:423211
CTD 11261
eggNOG COG5126
GeneTree ENSGT00760000119179
HOGENOM HOG000233019
HOVERGEN HBG105307
InParanoid Q5ZM44
KO K17610
OMA FQPISRV
OrthoDB EOG78M035
PhylomeDB Q5ZM44
TreeFam TF354284
Reactome REACT_320887
NextBio 20825713
PRO PR:Q5ZM44
Proteomes UP000000539
GO GO:0005737
GO:0005783
GO:0005793
GO:0070062
GO:0005925
GO:0000139
GO:0015630
GO:0005634
GO:0005886
GO:0030133
GO:0005509
GO:0048306
GO:0019900
GO:0008017
GO:0004860
GO:0005215
GO:0071468
GO:0031122
GO:0022406
GO:0061025
GO:0061024
GO:0001578
GO:0070885
GO:0032088
GO:0010923
GO:0031953
GO:0042308
GO:0006469
GO:0001933
GO:0031397
GO:0060050
GO:0090314
GO:0051222
GO:0032417
GO:0006611
GO:0050821
GO:0051453
GO:1901214
Gene3D 1.10.238.10
InterPro IPR011992
IPR018247
IPR002048
Pfam PF13499
SMART SM00054
PROSITE PS00018
PS50222

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0090314

positive regulation of protein targeting to membrane

PMID:17392381[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0071468

cellular response to acidic pH

PMID:17392381[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0070885

negative regulation of calcineurin-NFAT signaling cascade

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q99653

P

Seeded From UniProt

complete

involved_in

GO:0061025

membrane fusion

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P61023

P

Seeded From UniProt

complete

involved_in

GO:0061024

membrane organization

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P61023

P

Seeded From UniProt

complete

involved_in

GO:0060050

positive regulation of protein glycosylation

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P61023

P

Seeded From UniProt

complete

involved_in

GO:0051453

regulation of intracellular pH

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q99653

P

Seeded From UniProt

complete

involved_in

GO:0051222

positive regulation of protein transport

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P61023

P

Seeded From UniProt

complete

involved_in

GO:0050821

protein stabilization

PMID:17392381[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0048306

calcium-dependent protein binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q99653

F

Seeded From UniProt

complete

involved_in

GO:0042308

negative regulation of protein import into nucleus

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q99653

P

Seeded From UniProt

complete

involved_in

GO:0032417

positive regulation of sodium:proton antiporter activity

PMID:17392381[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0032417

positive regulation of sodium:proton antiporter activity

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q99653

P

Seeded From UniProt

complete

involved_in

GO:0032088

negative regulation of NF-kappaB transcription factor activity

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q99653

P

Seeded From UniProt

complete

involved_in

GO:0031953

negative regulation of protein autophosphorylation

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P61023

P

Seeded From UniProt

complete

involved_in

GO:0031397

negative regulation of protein ubiquitination

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P61023

P

Seeded From UniProt

complete

involved_in

GO:0031122

cytoplasmic microtubule organization

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P61023

P

Seeded From UniProt

complete

part_of

GO:0030133

transport vesicle

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P61023

C

Seeded From UniProt

complete

involved_in

GO:0022406

membrane docking

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P61023

P

Seeded From UniProt

complete

enables

GO:0019900

kinase binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P61023

F

Seeded From UniProt

complete

part_of

GO:0015630

microtubule cytoskeleton

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P61023

C

Seeded From UniProt

complete

involved_in

GO:0010923

negative regulation of phosphatase activity

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q99653

P

Seeded From UniProt

complete

enables

GO:0008017

microtubule binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P61023

F

Seeded From UniProt

complete

involved_in

GO:0006611

protein export from nucleus

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P61023

P

Seeded From UniProt

complete

involved_in

GO:0006469

negative regulation of protein kinase activity

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P61023

P

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q99653

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P61023

C

Seeded From UniProt

complete

part_of

GO:0005783

endoplasmic reticulum

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P61023

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P61023

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P61023

C

Seeded From UniProt

complete

enables

GO:0005509

calcium ion binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q99653

F

Seeded From UniProt

complete

enables

GO:0005215

transporter activity

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P61023

F

Seeded From UniProt

complete

involved_in

GO:0001933

negative regulation of protein phosphorylation

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P61023

P

Seeded From UniProt

complete

involved_in

GO:0001578

microtubule bundle formation

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P61023

P

Seeded From UniProt

complete

part_of

GO:0000139

Golgi membrane

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P61023

C

Seeded From UniProt

complete

involved_in

GO:1901214

regulation of neuron death

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q99653
ensembl:ENSP00000335632

P

Seeded From UniProt

complete

involved_in

GO:0070885

negative regulation of calcineurin-NFAT signaling cascade

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q99653
ensembl:ENSP00000335632

P

Seeded From UniProt

complete

involved_in

GO:0051453

regulation of intracellular pH

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q99653
ensembl:ENSP00000335632

P

Seeded From UniProt

complete

enables

GO:0048306

calcium-dependent protein binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q99653
ensembl:ENSP00000335632

F

Seeded From UniProt

complete

involved_in

GO:0042308

negative regulation of protein import into nucleus

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q99653
ensembl:ENSP00000335632

P

Seeded From UniProt

complete

involved_in

GO:0032417

positive regulation of sodium:proton antiporter activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q99653
ensembl:ENSP00000335632

P

Seeded From UniProt

complete

involved_in

GO:0032088

negative regulation of NF-kappaB transcription factor activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q99653
ensembl:ENSP00000335632

P

Seeded From UniProt

complete

involved_in

GO:0010923

negative regulation of phosphatase activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q99653
ensembl:ENSP00000335632

P

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q99653
ensembl:ENSP00000335632

C

Seeded From UniProt

complete

enables

GO:0005509

calcium ion binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q99653
ensembl:ENSP00000335632

F

Seeded From UniProt

complete

enables

GO:0005509

calcium ion binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002048

F

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1003
UniProtKB-SubCell:SL-0039

C

Seeded From UniProt

complete

part_of

GO:0005783

endoplasmic reticulum

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0256
UniProtKB-SubCell:SL-0095

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

enables

GO:0004860

protein kinase inhibitor activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0649

F

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472
UniProtKB-SubCell:SL-0162

C

Seeded From UniProt

complete

part_of

GO:0005856

cytoskeleton

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0206
UniProtKB-SubCell:SL-0090

C

Seeded From UniProt

complete

involved_in

GO:0015031

protein transport

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0653

P

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

part_of

GO:0012505

endomembrane system

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0147

C

Seeded From UniProt

complete

part_of

GO:0005793

endoplasmic reticulum-Golgi intermediate compartment

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0098

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 Matsushita, M et al. (2007) Loss of calcineurin homologous protein-1 in chicken B lymphoma DT40 cells destabilizes Na+/H+ exchanger isoform-1 protein. Am. J. Physiol., Cell Physiol. 293 C246-54 PubMed GONUTS page