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CHICK:CAV1

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) CAV1
Protein Name(s) Caveolin-1
External Links
UniProt P35431
EMBL L01582
RefSeq NP_001099134.1
UniGene Gga.5091
STRING 9031.ENSGALP00000038147
GeneID 373996
KEGG gga:373996
CTD 857
eggNOG NOG86001
HOGENOM HOG000036550
HOVERGEN HBG003422
InParanoid P35431
KO K06278
PhylomeDB P35431
NextBio 20813524
PRO PR:P35431
Proteomes UP000000539
GO GO:0005901
GO:0005768
GO:0000139
GO:0031295
InterPro IPR001612
IPR015504
IPR018361
PANTHER PTHR10844
PTHR10844:SF5
Pfam PF01146
PROSITE PS01210

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

part_of

GO:0005901

caveola

PMID:15272054[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0031295

T cell costimulation

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q03135

P

Seeded From UniProt

complete

part_of

GO:0005768

endosome

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q03135

C

Seeded From UniProt

complete

involved_in

GO:0070836

caveola assembly

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:102709
MGI:MGI:107570
PANTHER:PTN000851526
UniProtKB:P51636
UniProtKB:P56539
UniProtKB:Q03135

P

Seeded From UniProt

complete

involved_in

GO:0061099

negative regulation of protein tyrosine kinase activity

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:102709
PANTHER:PTN000090213
UniProtKB:Q03135

P

Seeded From UniProt

complete

part_of

GO:0048471

perinuclear region of cytoplasm

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:102709
PANTHER:PTN000090213
RGD:2280
UniProtKB:Q03135

C

Seeded From UniProt

complete

enables

GO:0044325

ion channel binding

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000090213
RGD:2280
UniProtKB:Q03135

F

Seeded From UniProt

complete

colocalizes_with

GO:0042383

sarcolemma

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:107570
PANTHER:PTN000090155
RGD:2281
UniProtKB:P56539
UniProtKB:P79132
UniProtKB:Q2KI43
UniProtKB:Q66WT7

C

Seeded From UniProt

complete

colocalizes_with

GO:0032991

protein-containing complex

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:102709
MGI:MGI:107571
PANTHER:PTN000090155
RGD:2280
RGD:2281
RGD:620348
UniProtKB:P51636
UniProtKB:Q03135

C

Seeded From UniProt

complete

enables

GO:0032947

protein-containing complex scaffold activity

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:102709
MGI:MGI:107571
PANTHER:PTN000851526
RGD:2281
UniProtKB:P56539

F

Seeded From UniProt

complete

part_of

GO:0031410

cytoplasmic vesicle

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000090213
RGD:2280
UniProtKB:Q03135

C

Seeded From UniProt

complete

involved_in

GO:0030154

cell differentiation

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000090155
RGD:2281

P

Seeded From UniProt

complete

enables

GO:0019901

protein kinase binding

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:102709
PANTHER:PTN000090213
UniProtKB:Q03135

F

Seeded From UniProt

complete

involved_in

GO:0006874

cellular calcium ion homeostasis

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:102709
PANTHER:PTN000090213
RGD:2280

P

Seeded From UniProt

complete

colocalizes_with

GO:0005925

focal adhesion

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:102709
MGI:MGI:107571
PANTHER:PTN000090155
RGD:2280
UniProtKB:P51636
UniProtKB:Q03135

C

Seeded From UniProt

complete

colocalizes_with

GO:0005901

caveola

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:102709
MGI:MGI:107570
PANTHER:PTN000851526
RGD:2280
RGD:2281
RGD:620348
UniProtKB:P33724
UniProtKB:P35431
UniProtKB:P51636
UniProtKB:P79132
UniProtKB:Q03135
UniProtKB:Q2KI43
UniProtKB:Q66WT7
UniProtKB:Q6RVA9

C

Seeded From UniProt

complete

part_of

GO:0005887

integral component of plasma membrane

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:102709
PANTHER:PTN000851526
UniProtKB:P51636
WB:WBGene00000301

C

Seeded From UniProt

complete

part_of

GO:0005794

Golgi apparatus

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:102709
PANTHER:PTN000090213
RGD:2280

C

Seeded From UniProt

complete

colocalizes_with

GO:0005737

cytoplasm

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000851526
RGD:2280
RGD:2281
RGD:620348

C

Seeded From UniProt

complete

enables

GO:0005198

structural molecule activity

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000851526
UniProtKB:P33724
UniProtKB:Q03135

F

Seeded From UniProt

complete

involved_in

GO:0001937

negative regulation of endothelial cell proliferation

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:102709
PANTHER:PTN000090213
RGD:2280

P

Seeded From UniProt

complete

part_of

GO:0005901

caveola

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR015504

C

Seeded From UniProt

complete

involved_in

GO:0070836

caveola assembly

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001612
InterPro:IPR015504

P

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1003
UniProtKB-SubCell:SL-0039

C

Seeded From UniProt

complete

part_of

GO:0005794

Golgi apparatus

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0333

C

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

part_of

GO:0005901

caveola

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0035

C

Seeded From UniProt

complete

part_of

GO:0045121

membrane raft

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0370

C

Seeded From UniProt

complete

part_of

GO:0000139

Golgi membrane

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0134

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Huhtakangas, JA et al. (2004) The vitamin D receptor is present in caveolae-enriched plasma membranes and binds 1 alpha,25(OH)2-vitamin D3 in vivo and in vitro. Mol. Endocrinol. 18 2660-71 PubMed GONUTS page
  2. 2.00 2.01 2.02 2.03 2.04 2.05 2.06 2.07 2.08 2.09 2.10 2.11 2.12 2.13 2.14 2.15 2.16 2.17 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page