CHICK:CAN3

Species (Taxon ID)	Gallus gallus (Chicken). (9031)
Gene Name(s)	CAPN3
Protein Name(s)	Calpain-3 Calcium-activated neutral proteinase 3 CANP 3 Calpain L3 Calpain p94 Muscle-specific calcium-activated neutral protease 3
External Links
UniProt	Q92177
EMBL	D38028
PIR	S57196
UniGene	Gga.72
ProteinModelPortal	Q92177
SMR	Q92177
STRING	9031.ENSGALP00000031999
MEROPS	C02.004
PaxDb	Q92177
PRIDE	Q92177
CTD	825
eggNOG	NOG327523
HOGENOM	HOG000232035
HOVERGEN	HBG012645
InParanoid	Q92177
PhylomeDB	Q92177
BRENDA	3.4.22.54
NextBio	20825732
PRO	PR:Q92177
Proteomes	UP000000539
GO	GO:0005737 GO:0005829 GO:0030016 GO:0005634 GO:0005886 GO:0043234 GO:0030315 GO:0030018 GO:0005509 GO:0004198 GO:0003824 GO:0055103 GO:0008233 GO:0032947 GO:0031402 GO:0008307 GO:0031432 GO:0071277 GO:0071472 GO:0061061 GO:0030239 GO:0043066 GO:0033234 GO:0045892 GO:0051092 GO:0045862 GO:0051281 GO:0014718 GO:0045893 GO:0006461 GO:0072657 GO:0006508 GO:0050790 GO:0043122 GO:0051592 GO:0014850 GO:0045214 GO:0097264
Gene3D	1.10.238.10
InterPro	IPR022684 IPR022682 IPR022683 IPR029531 IPR011992 IPR018247 IPR002048 IPR000169 IPR001300
PANTHER	PTHR10183:SF49
Pfam	PF01067 PF00036 PF13405 PF00648
PRINTS	PR00704
SMART	SM00720 SM00230 SM00054
SUPFAM	SSF49758
PROSITE	PS50203 PS00018 PS50222 PS00139

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
involved_in	GO:1990092	calcium-dependent self proteolysis	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P20807	P	Seeded From UniProt	complete
involved_in	GO:0097264	self proteolysis	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P20807	P	Seeded From UniProt	complete
involved_in	GO:0072657	protein localization to membrane	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q64691	P	Seeded From UniProt	complete
involved_in	GO:0071472	cellular response to salt stress	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q64691	P	Seeded From UniProt	complete
involved_in	GO:0071277	cellular response to calcium ion	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q64691	P	Seeded From UniProt	complete
involved_in	GO:0061061	muscle structure development	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q64691	P	Seeded From UniProt	complete
enables	GO:0055103	ligase regulator activity	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P20807	F	Seeded From UniProt	complete
involved_in	GO:0051592	response to calcium ion	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P16259	P	Seeded From UniProt	complete
involved_in	GO:0051281	positive regulation of release of sequestered calcium ion into cytosol	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q64691	P	Seeded From UniProt	complete
involved_in	GO:0051092	positive regulation of NF-kappaB transcription factor activity	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P20807	P	Seeded From UniProt	complete
involved_in	GO:0050790	regulation of catalytic activity	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P20807	P	Seeded From UniProt	complete
involved_in	GO:0045893	positive regulation of transcription, DNA-templated	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P20807	P	Seeded From UniProt	complete
involved_in	GO:0045892	negative regulation of transcription, DNA-templated	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q64691	P	Seeded From UniProt	complete
involved_in	GO:0045862	positive regulation of proteolysis	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q64691	P	Seeded From UniProt	complete
involved_in	GO:0045214	sarcomere organization	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q64691	P	Seeded From UniProt	complete
part_of	GO:0032991	protein-containing complex	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q64691	C	Seeded From UniProt	complete
involved_in	GO:0043122	regulation of I-kappaB kinase/NF-kappaB signaling	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q64691	P	Seeded From UniProt	complete
involved_in	GO:0043122	regulation of I-kappaB kinase/NF-kappaB signaling	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P20807	P	Seeded From UniProt	complete
involved_in	GO:0043066	negative regulation of apoptotic process	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q64691	P	Seeded From UniProt	complete
involved_in	GO:0043066	negative regulation of apoptotic process	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P20807	P	Seeded From UniProt	complete
involved_in	GO:0033234	negative regulation of protein sumoylation	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P20807	P	Seeded From UniProt	complete
enables	GO:0032947	protein-containing complex scaffold activity	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q64691	F	Seeded From UniProt	complete
enables	GO:0031432	titin binding	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P16259	F	Seeded From UniProt	complete
enables	GO:0031402	sodium ion binding	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q64691	F	Seeded From UniProt	complete
part_of	GO:0030315	T-tubule	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P16259	C	Seeded From UniProt	complete
involved_in	GO:0030239	myofibril assembly	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q64691	P	Seeded From UniProt	complete
part_of	GO:0030018	Z disc	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P16259	C	Seeded From UniProt	complete
part_of	GO:0030016	myofibril	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P16259	C	Seeded From UniProt	complete
involved_in	GO:0014850	response to muscle activity	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P16259	P	Seeded From UniProt	complete
involved_in	GO:0014718	positive regulation of satellite cell activation involved in skeletal muscle regeneration	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q64691	P	Seeded From UniProt	complete
enables	GO:0008307	structural constituent of muscle	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q64691	F	Seeded From UniProt	complete
enables	GO:0008233	peptidase activity	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P20807	F	Seeded From UniProt	complete
enables	GO:0008233	peptidase activity	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P16259	F	Seeded From UniProt	complete
involved_in	GO:0006508	proteolysis	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q64691	P	Seeded From UniProt	complete
involved_in	GO:0006508	proteolysis	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P20807	P	Seeded From UniProt	complete
involved_in	GO:0065003	protein-containing complex assembly	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q64691	P	Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q64691	C	Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P16259	C	Seeded From UniProt	complete
part_of	GO:0005829	cytosol	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q64691	C	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P20807	C	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P16259	C	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P20807	C	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P16259	C	Seeded From UniProt	complete
enables	GO:0005509	calcium ion binding	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q64691	F	Seeded From UniProt	complete
enables	GO:0004198	calcium-dependent cysteine-type endopeptidase activity	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q64691	F	Seeded From UniProt	complete
enables	GO:0004198	calcium-dependent cysteine-type endopeptidase activity	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P16259	F	Seeded From UniProt	complete
enables	GO:0003824	catalytic activity	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P20807	F	Seeded From UniProt	complete
involved_in	GO:0043066	negative regulation of apoptotic process	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:107437 PANTHER:PTN000021935 UniProtKB:P20807	P	Seeded From UniProt	complete
involved_in	GO:0006508	proteolysis	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0012051 FB:FBgn0025866 MGI:MGI:107437 MGI:MGI:88263 MGI:MGI:88264 PANTHER:PTN000021568 RGD:2267 RGD:2268 RGD:2269 RGD:69354 UniProtKB:P07384 UniProtKB:P20807 UniProtKB:P35750 UniProtKB:Q9HC96 WB:WBGene00006606	P	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0025866 FB:FBgn0260450 MGI:MGI:107437 MGI:MGI:88264 PANTHER:PTN000021568 RGD:2268 RGD:2269 RGD:69354 UniProtKB:P20807 UniProtKB:P35750 UniProtKB:Q8RVL2	C	Seeded From UniProt	complete
enables	GO:0004198	calcium-dependent cysteine-type endopeptidase activity	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0012051 FB:FBgn0025866 MGI:MGI:107437 MGI:MGI:2181366 MGI:MGI:88263 PANTHER:PTN000021568 RGD:2267 RGD:2269 RGD:69354 UniProtKB:P07384 UniProtKB:P17655 UniProtKB:P35750 UniProtKB:Q9HC96	F	Seeded From UniProt	complete
enables	GO:0004198	calcium-dependent cysteine-type endopeptidase activity	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0012051 FB:FBgn0025866 MGI:MGI:107437 MGI:MGI:2181366 MGI:MGI:88263 MGI:MGI:88264 PANTHER:PTN000021568 RGD:2267 RGD:2268 RGD:2269 RGD:69354 UniProtKB:P07384 UniProtKB:P17655 UniProtKB:P35750 UniProtKB:Q9HC96	F	Seeded From UniProt	complete
enables	GO:0004198	calcium-dependent cysteine-type endopeptidase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001300 InterPro:IPR022684 InterPro:IPR029531	F	Seeded From UniProt	complete
enables	GO:0005509	calcium ion binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002048	F	Seeded From UniProt	complete
involved_in	GO:0006508	proteolysis	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001300 InterPro:IPR022684 InterPro:IPR029531	P	Seeded From UniProt	complete
involved_in	GO:0045214	sarcomere organization	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR029531	P	Seeded From UniProt	complete
involved_in	GO:0006508	proteolysis	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0645	P	Seeded From UniProt	complete
enables	GO:0008233	peptidase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0645	F	Seeded From UniProt	complete
enables	GO:0008234	cysteine-type peptidase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0788	F	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0963 UniProtKB-SubCell:SL-0086	C	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0539 UniProtKB-SubCell:SL-0191	C	Seeded From UniProt	complete
enables	GO:0046872	metal ion binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0479	F	Seeded From UniProt	complete
enables	GO:0016787	hydrolase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0378	F	Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 ^1.3 ^1.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:21873635-1] 1.0 ^1.1 ^1.2 ^1.3 ^1.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

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CHICK:CAN3

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References

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