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CAEEL:NRDE3

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Species (Taxon ID) Caenorhabditis elegans. (6239)
Gene Name(s) nrde-3
Protein Name(s) Nuclear RNAi defective-3 protein
External Links
UniProt Q21691
EMBL FO080331
PIR T16676
RefSeq NP_508092.1
UniGene Cel.23517
ProteinModelPortal Q21691
SMR Q21691
DIP DIP-55715N
IntAct Q21691
STRING 6239.R04A9.2
PaxDb Q21691
EnsemblMetazoa R04A9.2
GeneID 180392
KEGG cel:CELE_R04A9.2
UCSC R04A9.2
CTD 180392
WormBase R04A9.2
eggNOG NOG310650
GeneTree ENSGT00760000119148
HOGENOM HOG000016330
InParanoid Q21691
OMA YTRGPNA
PhylomeDB Q21691
NextBio 909156
Proteomes UP000001940
GO GO:0005737
GO:0005634
GO:0031332
GO:0035197
GO:0006404
GO:0016246
InterPro IPR003100
IPR003165
IPR012337
Pfam PF02170
PF02171
SMART SM00949
SM00950
SUPFAM SSF101690
SSF53098
PROSITE PS50821
PS50822

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0005634

nucleus

PMID:20543824[1]

ECO:0000314

C

Figure 2B

complete
CACAO 7441

GO:1900368

regulation of RNA interference

PMID:18653886[2]

ECO:0000315

P

Figure 2

complete
CACAO 7317

part_of

GO:0005634

nucleus

PMID:20543824[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:1900368

regulation of RNA interference

PMID:18653886[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0008355

olfactory learning

PMID:23993094[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

occurs_in:(WBbt:0005672)

Seeded From UniProt

complete

part_of

GO:0031332

RNAi effector complex

PMID:23993094[3]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0035197

siRNA binding

PMID:23993094[3]

ECO:0000314

direct assay evidence used in manual assertion

F

has_direct_input:(WB:WBGene00003848)

Seeded From UniProt

complete

enables

GO:0035197

siRNA binding

PMID:18653886[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0016246

RNA interference

PMID:21901112[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

WB:WBVar00145447

P

Seeded From UniProt

complete

involved_in

GO:0016246

RNA interference

PMID:18653886[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

occurs_in:(GO:0005634)

Seeded From UniProt

complete

involved_in

GO:0006404

RNA import into nucleus

PMID:18653886[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:18653886[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0003676

nucleic acid binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003165
InterPro:IPR036397

F

Seeded From UniProt

complete

involved_in

GO:0031047

gene silencing by RNA

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0943

P

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Guang, S et al. (2010) Small regulatory RNAs inhibit RNA polymerase II during the elongation phase of transcription. Nature 465 1097-101 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 2.5 Guang, S et al. (2008) An Argonaute transports siRNAs from the cytoplasm to the nucleus. Science 321 537-41 PubMed GONUTS page
  3. 3.0 3.1 3.2 Juang, BT et al. (2013) Endogenous nuclear RNAi mediates behavioral adaptation to odor. Cell 154 1010-22 PubMed GONUTS page
  4. Burkhart, KB et al. (2011) A pre-mRNA-associating factor links endogenous siRNAs to chromatin regulation. PLoS Genet. 7 e1002249 PubMed GONUTS page